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2023 |
2022 |
2021 |
2020 |
2025
Cisneros, Angel, F.; Landry, Christian, R.. (2025) Simple genetic mechanisms toward more intricate molecular complexes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. DOI 10.1073/pnas.2500162122 (http://dx.doi.org/10.1073/pnas.2500162122)
Millette, Marc-Antoine; Coutinho, Ana; Prieto, Manuel; Salesse, Christian. (2025) Role of the Palmitoyl Group and of the Amphipathic α Helix in the Membrane Binding of the C-Terminus of G-Protein Receptor Kinase 4α/β. BIOCHEMISTRY. DOI 10.1021/acs.biochem.4c00492 (http://dx.doi.org/10.1021/acs.biochem.4c00492)
Tchara, Pata-Eting, Kougnassoukou; Loehr, Jeremy; Lambert, Jean-Philippe. (2025) Coupling Proximity Biotinylation with Genomic Targeting to Characterize Locus-Specific Changes in Chromatin Environments. JOURNAL OF PROTEOME RESEARCH. DOI 10.1021/acs.jproteome.4c00931 (http://dx.doi.org/10.1021/acs.jproteome.4c00931)
Vann, Kendra, R.; Sharma, Rajal; Hsu, Chih-Chao; Devoucoux, Maeva; Tencer, Adam, H.; Zeng, Lei; Lin, Kevin; Zhu, Li; Li, Qin; Lachance, Catherine; Ospina, Ruben, Rosas; Tong, Qiong; Cheung, Ka, Lung; Yang, Shuai; Biswas, Soumi; Xuan, Hongwen; Gatchalian, Jovylyn; Alamillo, Lorena; Wang, Jianlong; Jang, Suk, Min; Klein, Brianna, J.; Lu, Yue; Ernst, Patricia; Strahl, Brian, D.; Rothbart, Scott, B.; Walsh, Martin, J.; Cleary, Michael, L.; Cote, Jacques; Shi, Xiaobing; Zhou, Ming-Ming; Kutateladze, Tatiana, G.. (2025) Structure-function relationship of ASH1L and histone H3K36 and H3K4 methylation. NATURE COMMUNICATIONS. DOI 10.1038/s41467-025-57556-5 (http://dx.doi.org/10.1038/s41467-025-57556-5)
Mosterd, Cas; Moineau, Sylvain. (2025) Insight into crRNA Processing in Streptococcus mutans P42S and Application of SmutCas9 in Genome Editing. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI 10.3390/ijms26052005 (http://dx.doi.org/10.3390/ijms26052005)
Cashman-Kadri, Samuel; Fliss, Ismail; Beaulieu, Lucie; Lague, Patrick. (2025) Ergosterol depletion by fish AMP analogs likely enhances fungal membrane permeability. BIOPHYSICAL JOURNAL. DOI 10.1016/j.bpj.2025.02.015 (http://dx.doi.org/10.1016/j.bpj.2025.02.015)
Silva, Luiz Fernando, Lopes; Scholl, Juliete, Nathali; Weber, Augusto, Ferreira; Dias, Camila, Kehl; Pizzato, Pauline, Rafaela; Lima, Vinicius, Pierdona; Sévigny, Jean; Battastini, Ana Maria, Oliveira; Figueiro, Fabricio. (2025) Assessing the impact of CD73 inhibition on overcoming anti-EGFR resistance in glioma cells. ONCOLOGY RESEARCH. DOI 10.32604/or.2024.055508 (http://dx.doi.org/10.32604/or.2024.055508)
Boccacci, Yelena; Dumont, Nellie; Doyon, Yannick; Laganiere, Josée. (2025) CRISPR-Cas9-driven antigen conversion of clinically relevant blood group systems. HUMAN MOLECULAR GENETICS. DOI 10.1093/hmg/ddaf040 (http://dx.doi.org/10.1093/hmg/ddaf040)
Raiche-Marcoux, Gabrielle; Methot, Sebastien; Tchatchouang, Ange; Bettoli, Camille; Maranda, Cloe; Loiseau, Alexis; Proulx, Stephanie; Rochette, Patrick, J.; Genin, Emilie; Boisselier, Élodie. (2025) Localization of fluorescent gold nanoparticles throughout the eye after topical administration. FRONTIERS IN MEDICINE. DOI 10.3389/fmed.2025.1557611 (http://dx.doi.org/10.3389/fmed.2025.1557611)
Lau, Hayley, R.; Smith, Hayley, S.; Alural, Begum; Martin, Claire, E.; New, Laura, A.; Tilak, Manali; Banerjee, Sara, L.; Robeson, Hannah, N.; Bisson, Nicolas; Gingras, Anne-Claude; Lalonde, Jasmin; Jones, Nina. (2025) ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling. MOLECULAR ONCOLOGY. DOI 10.1002/1878-0261.70022 (http://dx.doi.org/10.1002/1878-0261.70022)
Bi, Chunyang; Mirza, Salahuddin; Baburi, Helay; Schaekel, Laura; Winzer, Riekje; Moschuetz, Susanne; Keetz, Kilian; Lopez, Vittoria; Pelletier, Julie; Sevigny, Jean; zur Wiesch, Julian, Schulze; Claff, Tobias; Tolosa, Eva; Namasivayam, Vigneshwaran; Straeter, Norbert; Mueller, Christa, E.. (2025) Synthesis, Characterization, Interactions, and Immunomodulatory Function of Ectonucleotidase CD39/CD73 Inhibitor 8-Butylthioadenosine 5′-Monophosphate. ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE. DOI 10.1021/acsptsci.5c00126 (http://dx.doi.org/10.1021/acsptsci.5c00126)
Verret, Laurianne; Burchell-Reyes, Kelly ; Morin, Jean-Francois ; Paquin, Jean-Francois. (2025) Exploration of 2-(pentafluoro-λ6-sulfanyl)ethane-1-sulfonyl chloride as a novel pentafluorosulfanylation reagent. JOURNAL OF FLUORINE CHEMISTRY. DOI 10.1016/j.jfluchem.2024.110387 (http://dx.doi.org/10.1016/j.jfluchem.2024.110387)
Bahadori, Sam; Leclerc, Christina; St-Gelais, Jacob; Poulin, Guillaume; Giguere, Denis. (2025) Catalyst-Controlled, Site-Selective Functionalization of Levoglucosan Analogues Mediated by Chiral Zinc Diamine Complexes. JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1021/acs.joc.4c02681 (http:dx.doi.org/10.1021/acs.joc.4c02681)
Prifti, Diogjena Katerina; Lauzier, Annie; Garand, Chantal; Calvo, Eva; Devillers, Romain; Roy, Suparba; Dos Santos, Alexsandro; Descombes, Laurence; Trudel, Benjamin; Laplante, Mathieu; Bordeleau, Francois; Elowe, Sabine. (2025) ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression. JOURNAL OF CELL BIOLOGY. DOI: 10.1083/jcb.202311194 (http:dx.doi.org/10.1083/jcb.202311194)
Mamjoud, Amal; Zirah, Severine; Biron, Eric; Fliss, Omar; Fliss, Ismail. (2025) In Vitro Insights into Bacteriocin-Mediated Modulation of Chicken Cecal Microbiota. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI : 10.3390/ijms26020755 (http:dx.doi.org/10.3390/ijms26020755)
Berger, Marie-Rose Ouellet-Du; Bouillon, Jean-Philippe; Paquin, Jean-Francois. (2025) Exploration towards the bromopentafluorosulfanylation reaction of terminal alkynes. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2024.110386 (http:dx.doi.org/10.1016/j.jfluchem.2024.110386)
Provencher, Luc; Nartey, Wilson; Brownlee, Peter M.; Atkins, Austin W.; Gagne, Jean-Philippe; Baudrier, Lou; Ting, Nicholas S. Y.;Piett, Cortt G.; Fang, Shujuan; Pearson, Dustin D.; Moore, Shaun; illon, Pierre; Nagel, Zachary D.; Poirier, Guy G.; Williams, Gareth J. ; Goodarzi, Aaron A. (2025) CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-025-56085-5 (http:dx.doi.org/10.1038/s41467-025-56085-5)
Kumar, Kiran; Arnold, Alexandre A.; Gauthier, Raphael; Mamone, Marius; Paquin, Jean-Francois; Warschawski, Dror E.; Marcotte, Isabelle. (2025) Simultaneous assessment of membrane bilayer structure and drug insertion by 19F solid-state NMR. BIOPHYSICAL JOURNAL. DOI: 10.1016/j.bpj.2024.11.3319 (http:dx.doi.org/10.1016/j.bpj.2024.11.3319)
A multivalent engagement of ENL with MOZ. NATURE STRUCTURAL & MOLECULAR BIOLOGY. DOI :10.1038/s41594-024-01455-8 (http:dx.doi.org/ 10.1038/s41594-024-01455-8)
2024
Belguesmia, Yanath; Guay, Louis-David; Teiar, Radja; Rahman, Md Ramim Tanver; Dussert, Elodie; Biron, Eric; Drider, Djamel. (2024). Synthesis, antimicrobial activity, and mechanistic studies of enterocin DD14, a leaderless two-peptide bacteriocin. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. DOI: 10.1016/j.ijbiomac.2024.135716 (http://dx.doi.org/10.1016/j.ijbiomac.2024.135716)
Berger, Alice; Pedersen, Jannie; Kowatsch, Monika M.; Scholte, Florine; Lafrance, Marc-Alexandre; Azizi, Hiva; Li, Yue; Gomez, Alejandro; Wade, Matthew; Fausther-Bovendo, Hugues; de la Vega, Marc-Antoine; Jelinski, Joseph; Babuadze, George; Nepveu-Traversy, Marie-Edith; Lamarre, Claude; Racine, Trina; Kang, Chil-Yong; Gaillet, Bruno; Garnier, Alain; Gilbert, Renald; Kamen, Amine; Yao, Xiao-Jian; Fowke, Keith R.; Arts, Eric; Kobinger, Gary. (2024). Impact of Recombinant VSV-HIV Prime, DNA-Boost Vaccine Candidates on Immunogenicity and Viremia on SHIV-Infected Rhesus Macaques. VACCINES. DOI: 10.3390/vaccines12040369 (http://dx.doi.org/10.3390/vaccines12040369)
Bergeron, Catherine; Berube, Christopher; Lamb, Henry; Koda, Yasuko; Craik, David J.; Henriques, Sonia Troeira; Voyer, Normand; Lawrence, Nicole. (2024). Analogs of Cyclic Peptide Mortiamide-D From Marine Fungi Have Improved Membrane Permeability and Kill Drug-Resistant Melanoma Cells. PEPTIDE SCIENCE. DOI: 10.1002/pep2.24380 (http://dx.doi.org/10.1002/pep2.24380)
Bahadori, Sam; Archambault, Marie-Jeanne; Sebastiao, Mathew; Bourgault, Steve; Giguere, Denis. (2024). Convergent Synthesis of a Group B Streptococcus Type III Epitope Toward a Semisynthetic Carbohydrate-Based Vaccine. JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1021/acs.joc.4c01216 (http://dx.doi.org/10.1021/acs.joc.4c01216)
Yokoyama, Akihiko; Niida, Hiroyuki; Kutateladze, Tatiana G.; Cote, Jacques. (2024). HBO1, a MYSTerious KAT and its links to cancer. BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS. DOI: 10.1016/j.bbagrm.2024.195045 (http://dx.doi.org/10.1016/j.bbagrm.2024.195045)
Alzahrani, Abdullah Yahya Abdullah; Hameed, Abdul; Khan, Abdul Rehman; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2024). Design, synthesis and in vitro evaluation of novel sulfonylurea and sulfonylthiourea as ectonucleotidases inhibitors. RESULTS IN CHEMISTRY. DOI: 10.1016/j.rechem.2024.101548 (http://dx.doi.org/10.1016/j.rechem.2024.101548)
Garcia-Vela, Sara; Guay, Louis-David; Rahman, Md Ramim Tanver; Biron, Eric; Torres, Carmen; Fliss, Ismail. (2024). Antimicrobial Activity of Synthetic Enterocins A, B, P, SEK4, and L50, Alone and in Combinations, against Clostridium perfringens. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms25031597 (http://dx.doi.org/10.3390/ijms25031597)
Devillers, Romain; dos Santos, Alexsandro; Destombes, Quentin; Laplante, Mathieu; Elowe, Sabine. (2024). Recent insights into the causes and consequences of chromosome mis-segregation. ONCOGENE. DOI: 10.1038/s41388-024-03163-5 (http://dx.doi.org/10.1038/s41388-024-03163-5)
Zhang, Qianyi E.; Lindenberger, Jared; Parsons, Ruth J.; Thakur, Bhishem; Parks, Rob; Park, Chan Soo; Huang, Xiao; Sammour, Salam; Janowska, Katarzyna; Spence, Taylor N.; Edwards, Robert J.; Martin, Mitchell; Williams, Wilton B.; Gobeil, Sophie; Montefiori, David C.; Korber, Bette; Saunders, Kevin O.; Haynes, Barton F.; Henderson, Rory; Acharya, Priyamvada. (2024). SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition. MOLECULAR CELL. DOI: 10.1016/j.molcel.2024.06.028 (http://dx.doi.org/10.1016/j.molcel.2024.06.028)
Wu, Xiangni; Chen, Pin-, I; Whitener, Robert L.; MacDougall, Matthew S.; Coykendall, Vy M. N.; Yan, Hao; Kim, Yong Bin; Harper, William; Pathak, Shiva; Iliopoulou, Bettina P.; Hestor, Allison; Saunders, Diane C.; Spears, Erick; Sevigny, Jean; Maahs, David M.; Basina, Marina; Sharp, Seth A.; Gloyn, Anna L.; Powers, Alvin C.; Kim, Seung K.; Jensen, Kent P.; Meyer, Everett H.. (2024). CD39 delineates chimeric antigen receptor regulatory T cell subsets with distinct cytotoxic & regulatory functions against human islets. FRONTIERS IN IMMUNOLOGY. DOI: 10.3389/fimmu.2024.1415102 (http://dx.doi.org/10.3389/fimmu.2024.1415102)
Kumar, Kiran; Arnold, Alexandre A.; Gauthier, Raphael; Mamone, Marius; Paquin, Jean-Francois; Warschawski, Dror E.; Marcotte, Isabelle. (2024). 19F solid-state NMR approaches to probe antimicrobial peptide interactions with membranes in whole cells. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. DOI: 10.1016/j.bbamem.2023.184269 (http://dx.doi.org/10.1016/j.bbamem.2023.184269)
Hossain, M. Iqbal; Lee, Jun Hee; Gagne, Jean-Philippe; Khan, Junaid; Poirier, Guy G.; King, Peter H.; Dawson, Valina L.; Dawson, Ted M.; Andrabi, Shaida A.. (2024). Poly(ADP-ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation. FASEB JOURNAL. DOI: 10.1096/fj.202302559R (http://dx.doi.org/10.1096/fj.202302559R)
Larnac, Eloise; Methot, Sebastien; Pelchat, Frederic; Millette, Marc-Antoine; Montoni, Alicia; Salesse, Christian; Haydont, Valerie; Marrot, Laurent; Rochette, Patrick J.. (2024). Synergistic Toxicity of Pollutant and Ultraviolet Exposure from a Mitochondrial Perspective. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms25179146 (http://dx.doi.org/10.3390/ijms25179146)
Tasleem, Mussarat; Pelletier, Julie; Sevigny, Jean; Hussain, Zahid; Khan, Ajmal; Al-Harrasi, Ahmed; El-kott, Attalla F.; Taslimi, Parham; Negm, Sally; Shafiq, Zahid; Iqbal, Jamshed. (2024). Synthesis, in vitro, and in silico studies of morpholine-based thiosemicarbazones as ectonucleotide pyrophosphatase/ phosphodiesterase-1 and-3 inhibitors. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. DOI: 10.1016/j.ijbiomac.2024.131068 (http://dx.doi.org/10.1016/j.ijbiomac.2024.131068)
Dion, Moira B.; Shah, Shiraz A.; Deng, Ling; Thorsen, Jonathan; Stokholm, Jakob; Krogfelt, Karen A.; Schjorring, Susanne; Horvath, Philippe; Allard, Antoine; Nielsen, Dennis S.; Petit, Marie-Agnes; Moineau, Sylvain. (2024). Escherichia coli CRISPR arrays from early life fecal samples preferentially target prophages. ISME JOURNAL. DOI: 10.1093/ismejo/wrae005 (http://dx.doi.org/10.1093/ismejo/wrae005)
Ye, Danrong; Nguyen, Phuong Trang; Bourgault, Steve; Couture, Manon. (2024). The heme binding protein ChuX is a regulator of heme degradation by the ChuS protein in Escherichia coli O157:H7. JOURNAL OF INORGANIC BIOCHEMISTRY. DOI: 10.1016/j.jinorgbio.2024.112575 (http://dx.doi.org/10.1016/j.jinorgbio.2024.112575)
Gaurav, Nitika; Kanai, Akinori; Lachance, Catherine; Cox, Khan L.; Liu, Jiuyang; Grzybowski, Adrian T.; Saksouk, Nehme; Klein, Brianna J.; Komata, Yosuke; Asada, Shuhei; Ruthenburg, Alexander J.; Poirier, Michael G.; Cote, Jacques; Yokoyama, Akihiko; Kutateladze, Tatiana G.. (2024). Guiding the HBO1 complex function through the JADE subunit. NATURE STRUCTURAL & MOLECULAR BIOLOGY. DOI: 10.1038/s41594-024-01245-2 (http://dx.doi.org/10.1038/s41594-024-01245-2)
Collin, Vanessa; Biquand, Elise; Tremblay, Vincent; Lavoie, Elise G.; Blondeau, Andreanne; Gravel, Annie; Galloy, Maxime; Lashgari, Anahita; Dessapt, Julien; Cote, Jacques; Flamand, Louis; Fradet-Turcotte, Amelie. (2024). The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling. EMBO REPORTS. DOI: 10.1038/s44319-023-00035-z (http://dx.doi.org/10.1038/s44319-023-00035-z)
Ashour, Kholoud; Sali, Sujitha; Aldoukhi, Ali H.; Hall, Derek; Mubaid, Souad; Busque, Sandrine; Lian, Xian Jin; Gagne, Jean-Philippe; Khattak, Shahryar; Di Marco, Sergio; Poirier, Guy G.; Gallouzi, Imed-Eddine. (2024). pADP-ribosylation regulates the cytoplasmic localization, cleavage, and pro-apoptotic function of HuR. LIFE SCIENCE ALLIANCE. DOI: 10.26508/lsa.202302316 (http://dx.doi.org/10.26508/lsa.202302316)
Bradley, David; Garand, Chantal; Belda, Hugo; Gagnon-Arsenault, Isabelle; Treeck, Moritz; Elowe, Sabine; Landry, Christian R.. (2024). The substrate quality of CK2 target sites has a determinant role on their function and evolution. CELL SYSTEMS. DOI: 10.1016/j.cels.2024.05.005 (http://dx.doi.org/10.1016/j.cels.2024.05.005)
Fliss, Omar; Guay, Louis-David; Fliss, Ismail; Biron, Eric. (2024). Synthesis and structure-activity study of the antimicrobial lipopeptide brevibacillin. RSC MEDICINAL CHEMISTRY. DOI: 10.1039/d4md00612g (http://dx.doi.org/10.1039/d4md00612g)
Hosseini, Nava; Chehreghani, Mahdi; Moineau, Sylvain; Charette, Steve J.. (2024). Centroid of the bacterial growth curves: a metric to assess phage efficiency. COMMUNICATIONS BIOLOGY. DOI: 10.1038/s42003-024-06379-z (http://dx.doi.org/10.1038/s42003-024-06379-z)
Lessard, Olivier; Laine, Danny; Giguere, Denis. (2024). Polyhalogenated Carbohydrates: Synthesis and Applications of Sugar Halides from Fluorine to Iodine. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1002/ejoc.202400120 (http://dx.doi.org/10.1002/ejoc.202400120)
Gandon, Sylvain; Guillemet, Martin; Gatchitch, Francois; Nicot, Antoine; Renaud, Ariane C.; Tremblay, Denise M.; Moineau, Sylvain. (2024). Building pyramids against the evolutionary emergence of pathogens. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. DOI: 10.1098/rspb.2023.1529 (http://dx.doi.org/10.1098/rspb.2023.1529)
Sorroza-Martinez, Luis; Pelletier, Mia; Guay, David; Gaillet, Bruno. (2024). Recent Advances in Therapeutics and Manufacturing Processes of Recombinant Adeno-Associated Virus for the Treatment of Lung Diseases. CURRENT GENE THERAPY. DOI: 10.2174/0115665232294935240826061311 (http://dx.doi.org/10.2174/0115665232294935240826061311)
Lachance, Gabriel P.; Chamelot, Guillaume; Morin, Jean-Francois; Boisselier, Elodie; Boukadoum, Mounir; Miled, Amine. (2024). Compact Poly/Monochromatic Colorimetric Sensing System With Integrated Microfluidic Sampler. IEEE SENSORS JOURNAL. DOI: 10.1109/JSEN.2024.3442553 (http://dx.doi.org/10.1109/JSEN.2024.3442553)
Kammoe, Romuald Brice Babou; Sevigny, Jean. (2024). Extracellular nucleotides in smooth muscle contraction. BIOCHEMICAL PHARMACOLOGY. DOI: 10.1016/j.bcp.2023.116005 (http://dx.doi.org/10.1016/j.bcp.2023.116005)
Henault, Mathieu; Marsit, Souhir; Charron, Guillaume; Landry, Christian R.. (2024). The genomic landscape of transposable elements in yeast hybrids is shaped by structural variation and genotype-specific modulation of transposition rate. ELIFE. DOI: 10.7554/eLife.89277 (http://dx.doi.org/10.7554/eLife.89277)
Rivest, Jean-Francois; Carter, Sophie; Goupil, Claudia; Anterieux, Penelope; Cyr, Denis; Ung, Roth-Visal; Dal Soglio, Dorothee; Mac-Way, Fabrice; Waters, Paula J.; Paganelli, Massimiliano; Doyon, Yannick. (2024). In vivo dissection of the mouse tyrosine catabolic pathway with CRISPR-Cas9 identifies modifier genes affecting hereditary tyrosinemia type 1. GENETICS. DOI: 10.1093/genetics/iyae139 (http://dx.doi.org/10.1093/genetics/iyae139)
Rouleau, Francois D.; Dube, Alexandre K.; Gagnon-Arsenault, Isabelle; Dibyachintan, Soham; Pageau, Alicia; Despres, Philippe C.; Lague, Patrick; Landry, Christian R.. (2024). Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate. PLOS GENETICS. DOI: 10.1371/journal.pgen.1011252 (http://dx.doi.org/10.1371/journal.pgen.1011252)
Bourguignon, Lea; Hetu-Arbour, Roxann; Charpentier, Tania; Bolduc, Marilene; Leclerc, Denis; Heinonen, Krista M.; Lamarre, Alain. (2024). Systemic administration of a viral nanoparticle neoadjuvant prevents lung metastasis development through emergency myelopoiesis. ONCOIMMUNOLOGY. DOI: 10.1080/2162402X.2024.2429846 (http://dx.doi.org/10.1080/2162402X.2024.2429846)
Champeil, Juliette; Mangion, Mathias; Gilbert, Renald; Gaillet, Bruno. (2024). Improved Manufacturing Methods of Extracellular Vesicles Pseudotyped with the Vesicular Stomatitis Virus Glycoprotein. MOLECULAR BIOTECHNOLOGY. DOI: 10.1007/s12033-023-01007-3 (http://dx.doi.org/10.1007/s12033-023-01007-3)
Mastalerz, Vincent; Verret, Laurianne; Paquin, Jean-Francois. (2024). Synthesis of 2-(Pentafluoro-λ6-sulfanyl)acetamides and Impact of the Fluorinated Group on the Lipophilicity. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1002/ejoc.202400956 (http://dx.doi.org/10.1002/ejoc.202400956)
Binet, Romuald; Lambert, Jean-Philippe; Tomkova, Marketa; Tischfield, Samuel; Baggiolini, Arianna; Picaud, Sarah; Sarkar, Sovan; Louphrasitthiphol, Pakavarin; Dias, Diogo; Carreira, Suzanne; Humphrey, Timothy C.; Fillipakopoulos, Panagis; White, Richard; Goding, Colin R.. (2024). DNA damage remodels the MITF interactome to increase melanoma genomic instability. GENES & DEVELOPMENT. DOI: 10.1101/gad.350740.123 (http://dx.doi.org/10.1101/gad.350740.123)
Pronovost, Raphael; Rion, Mathis; Tzouras, Nikolaos V.; Nolan, Steven P.; Paquin, Jean-Francois. (2024). Gold-catalyzed hydrofluorination of terminal alkynes using potassium bifluoride (KHF2). CHEMICAL COMMUNICATIONS. DOI: 10.1039/d4cc05049e (http://dx.doi.org/10.1039/d4cc05049e)
Mubaid, Souad; Sanchez, Brenda Janice; Algehani, Rinad A.; Skopenkova, Viktoriia; Adjibade, Pauline; Hall, Derek T.; Busque, Sandrine; Lian, Xian Jin; Ashour, Kholoud; Tremblay, Anne-Marie K.; Carlile, Graeme; Gagne, Jean-Philippe; Diaz-Gaxiola, Andrea; Khattak, Shahryar; Di Marco, Sergio; Thomas, David Y.; Poirier, Guy G.; Gallouzi, Imed-Eddine. (2024). Tankyrase-1 regulates RBP-mediated mRNA turnover to promote muscle fiber formation. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkae059 (http://dx.doi.org/10.1093/nar/gkae059)
Despres, Philippe C.; Dube, Alexandre K.; Picard, Marie-Eve; Grenier, Jordan; Shi, Rong; Landry, Christian R.. (2024). Compensatory mutations potentiate constructive neutral evolution by gene duplication. SCIENCE. DOI: 10.1126/science.ado5719 (http://dx.doi.org/10.1126/science.ado5719)
Tong, Xiao-Yang; Zhang, Yi; Pang, Jin-Xin; Liu, Bao-Lin; Biron, Eric; Rahman, Md R. T.; Qiao, Yong-Jin; Bing, Qi-Jie; Gao, Xu-Ying. (2024). Application of the Effect of Nonthermal Technologies on the Oxidation of Proteins and Lipids in Pigeon Meat during Chilled Storage. JOURNAL OF FOOD BIOCHEMISTRY. DOI: 10.1155/2024/6696954 (http://dx.doi.org/10.1155/2024/6696954)
Cashman-Kadri, Samuel; Lague, Patrick; Subirade, Muriel; Fliss, Ismail; Beaulieu, Lucie. (2024). Insights into Molecular Interactions between a GAPDH-Related Fish Antimicrobial Peptide, Analogs Thereof, and Bacterial Membranes. BIOCHEMISTRY. DOI: 10.1021/acs.biochem.4c00049 (http://dx.doi.org/10.1021/acs.biochem.4c00049)
Teyssier, Valentine; Williamson, Casey R.; Shata, Erka; Rosen, Stephanie P.; Jones, Nina; Bisson, Nicolas. (2024). Adapting to change: resolving the dynamic and dual roles of NCK1 and NCK2. BIOCHEMICAL JOURNAL. DOI: 10.1042/BCJ20230232 (http://dx.doi.org/10.1042/BCJ20230232)
Gunathilake, K. M. Damitha; Makumi, Angela; Loignon, Stephanie; Tremblay, Denise; Labrie, Simon; Svitek, Nicholas; Moineau, Sylvain. (2024). Diversity of Salmonella enterica phages isolated from chicken farms in Kenya. MICROBIOLOGY SPECTRUM. DOI: 10.1128/spectrum.02729-23 (http://dx.doi.org/10.1128/spectrum.02729-23)
Iqbal, Jamshed; Bano, Sehrish; Khan, Imtiaz Ali; Sevigny, Jean; Huang, Qing. (2024). Ectonucleotidase inhibitors: an updated patent review (2017-2023). EXPERT OPINION ON THERAPEUTIC PATENTS. DOI: 10.1080/13543776.2024.2423023 (http://dx.doi.org/10.1080/13543776.2024.2423023)
Paquin, Pascal; DeGrace, Nicolas; Belanger-Chabot, Guillaume; Paquin, Jean-Francois. (2024). Synthesis of Substituted Pentafluorosulfanylpyrazoles Under Flow Conditions. JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1021/acs.joc.3c02295 (http://dx.doi.org/10.1021/acs.joc.3c02295)
Bedard, Camille; Gagnon-Arsenault, Isabelle; Boisvert, Jonathan; Plante, Samuel; Dube, Alexandre K.; Pageau, Alicia; Fijarczyk, Anna; Sharma, Jehoshua; Maroc, Laetitia; Shapiro, Rebecca S.; Landry, Christian R.. (2024). Most azole resistance mutations in the Candida albicans drug target confer cross-resistance without intrinsic fitness cost. NATURE MICROBIOLOGY. DOI: 10.1038/s41564-024-01819-2 (http://dx.doi.org/10.1038/s41564-024-01819-2)
Auger, Maud; Sorroza-Martinez, Luis; Brahiti, Nadine; Huppe, Carole-Ann; Faucher-Giguere, Laurence; Arbi, Imen; Hervault, Maxime; Cheng, Xue; Gaillet, Bruno; Couture, Frederic; Guay, David; Soultan, Al-Halifa. (2024). Enhancing peptide and PMO delivery to mouse airway epithelia by chemical conjugation with the amphiphilic peptide S10. MOLECULAR THERAPY NUCLEIC ACIDS. DOI: 10.1016/j.omtn.2024.102290 (http://dx.doi.org/10.1016/j.omtn.2024.102290)
Bautista, Carla; Gagnon-Arsenault, Isabelle; Utrobina, Mariia; Fijarczyk, Anna; Bendixsen, Devin P.; Stelkens, Rike; Landry, Christian R.. (2024). Hybrid adaptation is hampered by Haldane's sieve. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-024-54105-4 (http://dx.doi.org/10.1038/s41467-024-54105-4)
Bayat, Fereshteh; Hilal, Arwa; Thirugnanasampanthar, Mathura; Tremblay, Denise; Filipe, Carlos D. M.; Moineau, Sylvain; Didar, Tohid F.; Hosseinidoust, Zeinab. (2024). High throughput platform technology for rapid target identification in personalized phage therapy. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-024-49710-2 (http://dx.doi.org/10.1038/s41467-024-49710-2)
Oechslin, Frank; Zhu, Xiaojun; Morency, Carlee; Somerville, Vincent; Shi, Rong; Moineau, Sylvain. (2024). Fermentation Practices Select for Thermostable Endolysins in Phages. MOLECULAR BIOLOGY AND EVOLUTION. DOI: 10.1093/molbev/msae055 (http://dx.doi.org/10.1093/molbev/msae055)
Resch, Gregory; Brives, Charlotte; Debarbieux, Laurent; Hodges, Francesca E.; Kirchhelle, Claas; Laurent, Frederic; Moineau, Sylvain; Martins, Ana Filipa Moreira; Rohde, Christine. (2024). Between Centralization and Fragmentation: The Past, Present, and Future of Phage Collections. PHAGE-THERAPY APPLICATIONS AND RESEARCH. DOI: 10.1089/phage.2023.0043 (http://dx.doi.org/10.1089/phage.2023.0043)
Zhang, Yi; Xie, Guojia; Lee, Ji-Eun; Zandian, Mohamad; Sudarshan, Deepthi; Estavoyer, Benjamin; Benz, Caroline; Viita, Tiina; Asgaritarghi, Golareh; Lachance, Catherine; Messmer, Clemence; Simonetti, Leandro; Sinha, Vikrant Kumar; Lambert, Jean-Philippe; Chen, Yu-Wen; Wang, Shu-Ping; Ivarsson, Ylva; Affar, El Bachir; Cote, Jacques; Ge, Kai; Kutateladze, Tatiana G.. (2024). ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-024-49391-x (http://dx.doi.org/10.1038/s41467-024-49391-x)
Khodaparastasgarabad, Nastaran; Couture, Manon; Greener, Jesse. (2024). Dynamic Metabolic Bottlenecks of a Geobacter Sulfurreducens Bioelectrochemical System Studied Using Microfluidics and the Arrhenius Equation. CHEMCATCHEM. DOI: 10.1002/cctc.202401102 (http://dx.doi.org/10.1002/cctc.202401102)
Leclerc, Christina; St-Gelais, Jacob; Cecioni, Samy; Giguere, Denis. (2024). Synthesis and hydrolysis of aryl fluoroglycosides. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2023.110232 (http://dx.doi.org/10.1016/j.jfluchem.2023.110232)
Addablah, Audrey A.; Ngazoa-Kakou, Solange E.; Adioumani, Emmanuella A.; Labrie, Simon J.; Tremblay, Denise M.; Gunathilake, Damitha; Moineau, Sylvain. (2024). Complete genome of Escherichia phages Carena and JoYop. MICROBIOLOGY RESOURCE ANNOUNCEMENTS. DOI: 10.1128/mra.01233-23 (http://dx.doi.org/10.1128/mra.01233-23)
Morneau, Zacharie; Moineau, Sylvain. (2024). The double play of a phage HTH regulator. TRENDS IN MICROBIOLOGY. DOI: 10.1016/j.tim.2024.09.005 (http://dx.doi.org/10.1016/j.tim.2024.09.005)
Koirala, Manoj; Merindol, Natacha; Karimzadegan, Vahid; Gelinas, Sarah-Eve; Liyanage, Nuwan Sameera; Lamichhane, Basanta; Tobon, Maria Camila Garcia; Lague, Patrick; Desgagne-Penix, Isabel. (2024). Kinetic and in silico structural characterization of norbelladine O-methyltransferase of Amaryllidaceae alkaloids biosynthesis. JOURNAL OF BIOLOGICAL CHEMISTRY. DOI: 10.1016/j.jbc.2024.107649 (http://dx.doi.org/10.1016/j.jbc.2024.107649)
Bertrand, Xavier; Aissaoui, Doria; Col, Oceane Meryem; Pucheault, Mathieu; Chabaud, Laurent; Paquin, Jean-Francois. (2024). Improved conditions for the synthesis of tertiary fluorides using a KF/ H2SO4 combination. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2024.110338 (http://dx.doi.org/10.1016/j.jfluchem.2024.110338)
Rodriguez, Cristina Leal; Shah, Shiraz A.; Rasmussen, Morten Arendt; Thorsen, Jonathan; Boulund, Ulrika; Pedersen, Casper-Emil Tingskov; Castro-Mejia, Josue L.; Poulsen, Christina Egeo; Poulsen, Casper Sahl; Deng, Ling; Larsen, Frej Andreas Nohr; Widdowson, Michael; Zhang, Yichang; Sorensen, Soren J.; Moineau, Sylvain; Petit, Marie-Agnes; Chawes, Bo; Bonnelykke, Klaus; Nielsen, Dennis S.; Stokholm, Jakob. (2024). The infant gut virome is associated with preschool asthma risk independently of bacteria. NATURE MEDICINE. DOI: 10.1038/s41591-023-02685-x (http://dx.doi.org/10.1038/s41591-023-02685-x)
Fraser, Tommy; Harbour, Zakiel; Voyer, Normand; Cardinal, Sebastien. (2024). Chemo- and Regioselective Demethylation of 2-Bromo-α-resorcylic Acid Derivatives Using Alkylthiolate Salts. SYNLETT. DOI: 10.1055/a-2370-7112 (http://dx.doi.org/10.1055/a-2370-7112)
Yang, Zhenlin; Mameri, Amel; Cattoglio, Claudia; Lachance, Catherine; Florez Ariza, Alfredo Jose; Luo, Jie; Humbert, Jonathan; Sudarshan, Deepthi; Banerjea, Arul; Galloy, Maxime; Fradet-Turcotte, Amelie; Lambert, Jean-Philippe; Ranish, Jeff A.; Cote, Jacques; Nogales, Eva. (2024). Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex. SCIENCE. DOI: 10.1126/science.adl5816 (http://dx.doi.org/10.1126/science.adl5816)
Lachance, Gabriel Philippe; Gauvreau, Dominic; Boisselier, Elodie; Boukadoum, Mounir; Miled, Amine. (2024). Breaking Barriers: Exploring Neurotransmitters through In Vivo vs. In Vitro Rivalry. SENSORS. DOI: 10.3390/s24020647 (http://dx.doi.org/10.3390/s24020647)
Khodaparastasgarabad, Nastaran; Couture, Manon; Greener, Jesse. (2024). A microfluidic study of acetate conversion kinetics in a microbial electrolysis cell: The role of age, concentration and flow on biofilm permeability. SENSORS AND ACTUATORS B-CHEMICAL. DOI: 10.1016/j.snb.2024.135779 (http://dx.doi.org/10.1016/j.snb.2024.135779)
Yustis, Juan-Carlos; Devoucoux, Maeva; Cote, Jacques. (2024). The Functional Relationship Between RNA Splicing and the Chromatin Landscape. JOURNAL OF MOLECULAR BIOLOGY. DOI: 10.1016/j.jmb.2024.168614 (http://dx.doi.org/10.1016/j.jmb.2024.168614)
Cisneros, Angel F.; Nielly-Thibault, Lou; Mallik, Saurav; Levy, Emmanuel D.; Landry, Christian R.. (2024). Mutational biases favor complexity increases in protein interaction networks after gene duplication. MOLECULAR SYSTEMS BIOLOGY. DOI: 10.1038/s44320-024-00030-z (http://dx.doi.org/10.1038/s44320-024-00030-z)
Kulhankova, Katarina; Cheng, Anna X.; Traore, Soumba; Auger, Maud; Pelletier, Mia; Hervault, Maxime; Wells, Kevin D.; Green, Jonathan A.; Byrne, Addison; Nelson, Benjamin; Sponchiado, Mariana; Boosani, Chandra; Heffner, Caleb S.; Snow, Kathy J.; Murray, Stephen A.; Villacreses, Raul A.; Rector, Michael, V; Gansemer, Nicholas D.; Stoltz, David A.; Allamargot, Chantal; Couture, Frederic; Hemez, Colin; Hallee, Stephanie; Barbeau, Xavier; Harvey, Mario; Lauvaux, Coraline; Gaillet, Bruno; Newby, Gregory A.; Liu, David R.; McCray Jr, Paul B.; Guay, David. (2024). Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkae819 (http://dx.doi.org/10.1093/nar/gkae819)
de Melo, Alessandra G.; Morency, Carlee; Moineau, Sylvain. (2024). Virulence-associated factors as targets for phage infection. CURRENT OPINION IN MICROBIOLOGY. DOI: 10.1016/j.mib.2024.102471 (http://dx.doi.org/10.1016/j.mib.2024.102471)
Aube, Simon; Landry, Christian R.. (2024). How genotype-by-environment interactions on fitness emerge. NATURE ECOLOGY & EVOLUTION. DOI: 10.1038/s41559-024-02577-4 (http://dx.doi.org/10.1038/s41559-024-02577-4)
Mellouk, Abdelkader; Jaouen, Paul; Ruel, Louis-Jacques; Le, Michel; Martini, Cyrielle; Moraes, Trevor F.; El Bakkouri, Majida; Lague, Patrick; Boisselier, Elodie; Calmettes, Charles. (2024). POTRA domains of the TamA insertase interact with the outer membrane and modulate membrane properties. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. DOI: 10.1073/pnas.2402543121 (http://dx.doi.org/10.1073/pnas.2402543121)
Landry, Christian R.. (2024). Cellular evolution in the population genetics environment. TRENDS IN ECOLOGY & EVOLUTION. DOI: 10.1016/j.tree.2024.04.009 (http://dx.doi.org/10.1016/j.tree.2024.04.009)
Bradley, David; Hogrebe, Alexander; Dandage, Rohan; Dube, Alexandre K.; Leutert, Mario; Dionne, Ugo; Chang, Alexis; Villen, Judit; Landry, Christian R.. (2024). The fitness cost of spurious phosphorylation. EMBO JOURNAL. DOI: 10.1038/s44318-024-00200-7 (http://dx.doi.org/10.1038/s44318-024-00200-7)
2023
Gauthier, Raphael; Paquin, Jean-Francois. (2023). Hydrofluorination of Alkynes: From (E) to (Z). CHEMISTRY-A EUROPEAN JOURNAL. DOI: 10.1002/chem.202301896 (http://dx.doi.org/10.1002/chem.202301896)
Bertrand, Xavier; Pucheault, Mathieu; Chabaud, Laurent; Paquin, Jean-Francois. (2023). Synthesis of Tertiary Fluorides through an Acid-Mediated Deoxyfluorination of Tertiary Alcohols. JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1021/acs.joc.3c01558 (http://dx.doi.org/10.1021/acs.joc.3c01558)
Kienzle, Laura; Bettinazzi, Stefano; Choquette, Thierry; Brunet, Marie; Khorami, Hajar Hosseini; Jacques, Jean-Francois; Moreau, Mathilde; Roucou, Xavier; Landry, Christian R.; Angers, Annie; Breton, Sophie. (2023). A small protein coded within the mitochondrial canonical gene nd4 regulates mitochondrial bioenergetics. BMC BIOLOGY. DOI: 10.1186/s12915-023-01609-y (http://dx.doi.org/10.1186/s12915-023-01609-y)
Beneyton, Adele; Nonfoux, Louis; Gagne, Jean-Philippe; Rodrigue, Amelie; Kothari, Charu; Atalay, Nurgul; Hendzel, Michael J.; Poirier, Guy G.; Masson, Jean-Yves. (2023). The dynamic process of covalent and non-covalent PARylation in the maintenance of genome integrity: a focus on PARP inhibitors. NAR CANCER. DOI: 10.1093/narcan/zcad043 (http://dx.doi.org/10.1093/narcan/zcad043)
da Silva, Alisson Coldebella; Scholl, Juliete Nathali; de Fraga Dias, Amanda; Weber, Augusto Ferreira; Morrone, Fernanda Bueno; Cruz-Lopez, Olga; Conejo-Garcia, Ana; Campos, Joaquin Maria; Sevigny, Jean; Figueiro, Fabricio; Battastini, Ana Maria Oliveira. (2023). Preclinical evaluation of bozepinib in bladder cancer cell lines: modulation of the NPP1 enzyme. PURINERGIC SIGNALLING. DOI: 10.1007/s11302-023-09975-6 (http://dx.doi.org/10.1007/s11302-023-09975-6)
Tremblay, Thomas; Haguette, Penelope; Robert-Scott, Gabrielle; Alcee, Jessica B.; Berube, Christopher; Bergeron, Catherine; Voyer, Normand; Giguere, Denis. (2023). Synthesis of Lincosamide Analogues via Oxime Resin Aminolysis. SYNLETT. DOI: 10.1055/a-1948-7153 (http://dx.doi.org/10.1055/a-1948-7153)
Evans-Yamamoto, Daniel; Dube, Alexandre K.; Saha, Gourav; Plante, Samuel; Bradley, David; Gagnon-Arsenault, Isabelle; Landry, Christian R.. (2023). Parallel Nonfunctionalization of CK1δ/ε Kinase Ohnologs Following a Whole-Genome Duplication Event. MOLECULAR BIOLOGY AND EVOLUTION. DOI: 10.1093/molbev/msad246 (http://dx.doi.org/10.1093/molbev/msad246)
Berube, Christopher; Guay, Louis-David; Fraser, Tommy; Lapointe, Victor; Cardinal, Sebastien; Biron, Eric. (2023). Convenient route to Fmoc-homotyrosine via metallaphotoredox catalysis and its use in the total synthesis of anabaenopeptin cyclic peptides. ORGANIC & BIOMOLECULAR CHEMISTRY. DOI: 10.1039/d3ob01608k (http://dx.doi.org/10.1039/d3ob01608k)
Jadoon, Muhammad Siraj Khan; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2023). Synthesis of new class of indole acetic acid sulfonate derivatives as ectonucleotidases inhibitors. RSC ADVANCES. DOI: 10.1039/d3ra04266a (http://dx.doi.org/10.1039/d3ra04266a)
Cisneros, Angel F.; Gagnon-Arsenault, Isabelle; Dube, Alexandre K.; Despres, Philippe C.; Kumar, Pradum; Lafontaine, Kiana; Pelletier, Joelle N.; Landry, Christian R.. (2023). Epistasis between promoter activity and coding mutations shapes gene evolvability. SCIENCE ADVANCES. DOI: 10.1126/sciadv.add9109 (http://dx.doi.org/10.1126/sciadv.add9109)
Cardoso, Andreia Machado; Aneli, Nyasmin Mendes; Lammers, Monica; Manica, Aline; Zanini, Daniela; Maciel, Sarah Franco Vieira de Oliveira; Sevigny, Jean; Corralo, Vanessa da Silva; De Sa, Clodoaldo Antonio. (2023). Resistance training reduces platelet activation in hypertensive women: the role of purinergic signaling. JOURNAL OF HYPERTENSION. DOI: 10.1097/HJH.0000000000003529 (http://dx.doi.org/10.1097/HJH.0000000000003529)
El Zawily, Amr; Vizeacoumar, Frederick S.; Dahiya, Renuka; Banerjee, Sara L.; Bhanumathy, Kalpana K.; Elhasasna, Hussain; Hanover, Glinton; Sharpe, Jessica C.; Sanchez, Malkon G.; Greidanus, Paul; Stacey, R. Greg; Moon, Kyung-Mee; Alexandrov, Ilya; Himanen, Juha P.; Nikolov, Dimitar B.; Fonge, Humphrey; White, Aaron P.; Foster, Leonard J.; Wang, Bingcheng; Toosi, Behzad M.; Bisson, Nicolas; Mirzabekov, Tajib A.; Vizeacoumar, Franco J.; Freywald, Andrew. (2023). A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy. CLINICAL CANCER RESEARCH. DOI: 10.1158/1078-0432.CCR-22-2535 (http://dx.doi.org/10.1158/1078-0432.CCR-22-2535)
Bricha, Salma; Cote-Cyr, Melanie; Tremblay, Thomas; Nguyen, Phuong Trang; St-Louis, Philippe; Giguere, Denis; Archambault, Denis; Bourgault, Steve. (2023). Synthetic Multicomponent Nanovaccines Based on the Molecular Co-assembly of β-Peptides Protect against Influenza A Virus. ACS INFECTIOUS DISEASES. DOI: 10.1021/acsinfecdis.2c00610 (http://dx.doi.org/10.1021/acsinfecdis.2c00610)
Zaman, Gohar; Ullah, Saif; Uzair, Muhammad; Batool, Sania; Ahmad, Haseen; Ullah, Farman; Pelletier, Julia; Sevigny, Jean; Iqbal, Jamshed; Hassan, Abbas. (2023). Synthesis of Thieno[3,2-d]pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h-NTPDase Inhibitors. CHEMMEDCHEM. DOI: 10.1002/cmdc.202300165 (http://dx.doi.org/10.1002/cmdc.202300165)
Shahin, Afnan, I; Zaraei, Seyed-Omar; AlKubaisi, Bilal O.; Ullah, Saif; Anbar, Hanan S.; El-Gamal, Randa; Menon, Varsha; Abdel-Maksoud, Mohammed S.; Oh, Chang-Hyun; El-Awady, Raafat; Gelsleichter, Nicolly Espindola; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed; Al-Tel, Taleb H.; El-Gamal, Mohammed, I. (2023). Design and synthesis of new adamantyl derivatives as promising antiproliferative agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. DOI: 10.1016/j.ejmech.2022.114958 (http://dx.doi.org/10.1016/j.ejmech.2022.114958)
Tremblay, Thomas; Bergeron, Catherine; Gagnon, Dominic; Berube, Christopher; Voyer, Normand; Richard, Dave; Giguere, Denis. (2023). Squaramide Tethered Clindamycin, Chloroquine, and Mortiamide Hybrids: Design, Synthesi s , and Antimalarial Activity. ACS MEDICINAL CHEMISTRY LETTERS. DOI: 10.1021/acsmedchemlett.2c00531 (http://dx.doi.org/10.1021/acsmedchemlett.2c00531)
Berger, Marie-Rose Ouellet-Du; Boucher, Maxim; Paquin, Jean-Francois. (2023). Light-activation of SF5Cl for the atom transfer radical addition onto alkenes and alkynes. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2023.110131 (http://dx.doi.org/10.1016/j.jfluchem.2023.110131)
Mastalerz, Vincent; Lam, Kevin; Paquin, Jean-Francois. (2023). Exploration toward the synthesis of aliphatic SF5-containing compounds using the Kolbe reaction. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2023.110113 (http://dx.doi.org/10.1016/j.jfluchem.2023.110113)
Louphrasitthiphol, Pakavarin; Loffreda, Alessia; Pogenberg, Vivian; Picaud, Sarah; Schepsky, Alexander; Friedrichsen, Hans; Zeng, Zhiqiang; Lashgari, Anahita; Thomas, Benjamin; Patton, E. Elizabeth; Wilmanns, Matthias; Filippakopoulos, Panagis; Lambert, Jean-Philippe; Steingrimsson, Eirikur; Mazza, Davide; Goding, Colin R.. (2023). Acetylation reprograms MITF target selectivity and residence time. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-023-41793-7 (http://dx.doi.org/10.1038/s41467-023-41793-7)
Pimont-Farge, Mathilde; Perreault, Veronique; Brisson, Guillaume; Otis, Francois; Voyer, Normand; Suwal, Shyam; Pouliot, Yves; Doyen, Alain. (2023). Hydrogel formation from peptides of a B-lactoglobulin tryptic hydrolysate: Contribution of self-assembling peptide B-Lg f1-8. FOOD HYDROCOLLOIDS. DOI: 10.1016/j.foodhyd.2023.108765 (http://dx.doi.org/10.1016/j.foodhyd.2023.108765)
Seguin, Jean-Christophe; Gagnon, Dominic; Belanger, Sarah; Richard, Dave; Fernandez, Xavier; Boudreau, Stephane; Voyer, Normand. (2023). Chemical Composition and Antiplasmodial Activity of the Essential Oil of Rhododendron subarcticum Leaves from Nunavik, Quebec, Canada. ACS OMEGA. DOI: 10.1021/acsomega.3c00235 (http://dx.doi.org/10.1021/acsomega.3c00235)
Franca, Tanos C. C.; Goncalves, Arlan da Silva; Berube, Christopher; Voyer, Normand; Aubry, Norman; LaPlante, Steven R.. (2023). Determining the Predominant Conformations of Mortiamides A-D in Solution Using NMR Data and Molecular Modeling Tools. ACS OMEGA. DOI: 10.1021/acsomega.3c01206 (http://dx.doi.org/10.1021/acsomega.3c01206)
Gauthier, Raphael; Tzouras, Nikolaos V.; Nolan, Steven P.; Paquin, Jean-Francois. (2023). Exploiting the inductive effect of the trifluoromethyl group: regioselective gold-catalyzed hydration of 2,2,2-trifluoroethyl-substituted alkynes. CHEMICAL COMMUNICATIONS. DOI: 10.1039/d3cc02034g (http://dx.doi.org/10.1039/d3cc02034g)
Viita, Tiina; Cote, Jacques. (2023). The MOZ-BRPF1 acetyltransferase complex in epigenetic crosstalk linked to gene regulation, development, and human diseases. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. DOI: 10.3389/fcell.2022.1115903 (http://dx.doi.org/10.3389/fcell.2022.1115903)
Mameri, Amel; Cote, Jacques. (2023). JAZF1: A metabolic actor subunit of the NuA4/TIP60 chromatin modifying complex. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. DOI: 10.3389/fcell.2023.1134268 (http://dx.doi.org/10.3389/fcell.2023.1134268)
Gonthier, Kevin; Weidmann, Cindy; Berthiaume, Line; Jobin, Cynthia; Lacouture, Aurelie; Lafront, Camille; Harvey, Mario; Neveu, Bertrand; Loehr, Jeremy; Bergeron, Alain; Fradet, Yves; Lacombe, Louis; Riopel, Julie; Latulippe, Eva; Atallah, Chantal; Shum, Michael; Lambert, Jean-Philippe; Pouliot, Frederic; Pelletier, Martin; Audet-Walsh, Etienne. (2023). Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic-mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer. MOLECULAR ONCOLOGY. DOI: 10.1002/1878-0261.13441 (http://dx.doi.org/10.1002/1878-0261.13441)
Huang, Xiaofeng; Gu, Wei; Zhang, Jiaoyue; Lan, Ying; Colarusso, Jonathan L.; Li, Sanlan; Pertl, Christoph; Lu, Jiaqi; Kim, Hyunkee; Zhu, Jian; Breault, David T.; Sevigny, Jean; Zhou, Qiao. (2023). Stomach-derived human insulin-secreting organoids restore glucose homeostasis. NATURE CELL BIOLOGY. DOI: 10.1038/s41556-023-01130-y (http://dx.doi.org/10.1038/s41556-023-01130-y)
Sahraei, Abolfazl Alizadeh; Bohorquez, Barbara Mejia; Tremblay, Denise; Moineau, Sylvain; Garnier, Alain; Larachi, Faical; Lague, Patrick. (2023). Insight into the Binding Mechanisms of Quartz-Selective Peptides: Toward Greener Flotation Processes. ACS APPLIED MATERIALS & INTERFACES. DOI: 10.1021/acsami.3c01275 (http://dx.doi.org/10.1021/acsami.3c01275)
Naasani, Liliana I. Sous; Sevigny, Jean; Moulin, Veronique J.; Wink, Marcia Rosangela. (2023). UTP increases wound healing in the self assembled skin substitute (SASS). JOURNAL OF CELL COMMUNICATION AND SIGNALING. DOI: 10.1007/s12079-023-00725-2 (http://dx.doi.org/10.1007/s12079-023-00725-2)
Ledoux, Nassim; Lelong, Emeline I. J.; Simard, Alexandre; Hussein, Samer; Adjibade, Pauline; Lambert, Jean-Philippe; Mazroui, Rachid. (2023). The Identification of Nuclear FMRP Isoform Iso6 Partners. CELLS. DOI: 10.3390/cells12242807 (http://dx.doi.org/10.3390/cells12242807)
Zaigham, Zahid Hussain; Ullah, Saif; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed; Hassan, Abbas. (2023). Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h-NTPDases. RSC ADVANCES. DOI: 10.1039/d3ra03874b (http://dx.doi.org/10.1039/d3ra03874b)
Nielsen, Tue Kjaergaard; Forero-Junco, Laura Milena; Kot, Witold; Moineau, Sylvain; Hansen, Lars Hestbjerg; Riber, Leise. (2023). Detection of nucleotide modifications in bacteria and bacteriophages: Strengths and limitations of current technologies and software. MOLECULAR ECOLOGY. DOI: 10.1111/mec.16679 (http://dx.doi.org/10.1111/mec.16679)
Hanover, Glinton; Vizeacoumar, Frederick S.; Banerjee, Sara L.; Nair, Raveena; Dahiya, Renuka; Osornio-Hernandez, Ana I.; Morales, Alain Morejon; Freywald, Tanya; Himanen, Juha P.; Toosi, Behzad M.; Bisson, Nicolas; Vizeacoumar, Franco J.; Freywald, Andrew. (2023). Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR. CELL REPORTS. DOI: 10.1016/j.celrep.2023.112670 (http://dx.doi.org/10.1016/j.celrep.2023.112670)
Ferlet, Remy; Pucheault, Mathieu; Chabaud, Laurent; Paquin, Jean-Francois. (2023). Metal-Free Defluoroborylation of 3,3-Difluoropropenes. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1002/ejoc.202300731 (http://dx.doi.org/10.1002/ejoc.202300731)
Noronha-Matos, Jose Bernardo; Pinto-Cardoso, Rui; Bessa-Andres, Catarina; Magalhaes-Cardoso, Maria Teresa; Ferreirinha, Fatima; Costa, Maria Adelina; Marinhas, Jose; Freitas, Rolando; Lemos, Rui; Vilaca, Adelio; Oliveira, Antonio; Pelletier, Julie; Sevigny, Jean; Correia-de-Sa, Paulo. (2023). Silencing NTPDase3 activity rehabilitates the osteogenic commitment of post-menopausal stem cell bone progenitors. STEM CELL RESEARCH & THERAPY. DOI: 10.1186/s13287-023-03315-6 (http://dx.doi.org/10.1186/s13287-023-03315-6)
Boccacci, Yelena; Dumont, Nellie; Doyon, Yannick; Laganiere, Josee. (2023). Accessory-cell-free differentiation of hematopoietic stem and progenitor cells into mature red blood cells. CYTOTHERAPY. DOI: 10.1016/j.jcyt.2023.07.007 (http://dx.doi.org/10.1016/j.jcyt.2023.07.007)
da Silva, Walmir; Ribeiro, Isadora Cunha; Agripino, Joice de Melo; Ferraz da Silva, Victor Hugo; de Souza, Luciana Angelo; Oliveira, Tatiana Aparecida; Bressan, Gustavo Costa; Vasconcellos, Raphael de Souza; Dumas, Carole; Pelletier, Julie; Sevigny, Jean; Papadopoulou, Barbara; Rangel Fietto, Juliana Lopes. (2023). Leishmania infantum NTPDase1 and NTPDase2 play an important role in infection and nitric oxide production in macrophages. ACTA TROPICA. DOI: 10.1016/j.actatropica.2022.106732 (http://dx.doi.org/10.1016/j.actatropica.2022.106732)
Jolicoeur, Alice P.; Lemay, Marie-Laurence; Beaubien, Elyse; Belanger, Jessy; Bergeron, Claudia; Bourque-Leblanc, Francoise; Dore, Laurie; Dupuis, Marie-Eve; Fleury, Audrey; Garneau, Josiane E.; Labrie, Simon J.; Labrie, Steve; Lacasse, Genevieve; Lamontagne-Drolet, Marianne; Lessard-Hurtubise, Roxanne; Martel, Bruno; Menasria, Rym; Morin-Pelchat, Rachel; Pageau, Gabrielle; Samson, Julie E.; Rousseau, Genevieve M.; Tremblay, Denise M.; Duquenne, Manon; Lamoureux, Maryse; Moineau, Sylvain. (2023). Longitudinal Study of Lactococcus Phages in a Canadian Cheese Factory. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. DOI: 10.1128/aem.00421-23 (http://dx.doi.org/10.1128/aem.00421-23)
Biot-Pelletier, Damien; Bettinazzi, Stefano; Gagnon-Arsenault, Isabelle; Dube, Alexandre K.; Bedard, Camille; Nguyen, Tuc H. M.; Fiumera, Heather L.; Breton, Sophie; Landry, Christian R.. (2023). Evolutionary Trajectories are Contingent on Mitonuclear Interactions. MOLECULAR BIOLOGY AND EVOLUTION. DOI: 10.1093/molbev/msad061 (http://dx.doi.org/10.1093/molbev/msad061)
Naasani, Liliana Ivet Sous; Pretto, Luiza; Zanatelli, Carla; Paim, Thais Casagrande; Souza, Aline Francielle Damo; Pase, Pablo Fagundes; Fernandes, Marilda Da Cruz; Sevigny, Jean; Wink, Marcia Rosangela. (2023). Bioscaffold developed with decellularized human amniotic membrane seeded with mesenchymal stromal cells: assessment of efficacy and safety profiles in a second-degree burn preclinical model. BIOFABRICATION. DOI: 10.1088/1758-5090/ac9ff4 (http://dx.doi.org/10.1088/1758-5090/ac9ff4)
Greschner, Andrea A.; Brahiti, Nadine; Auger, Maud; Hu, Lei; Abyaneh, Hoda Soleymani; Barbeau, Xavier; Parent, Victor; Gaillet, Bruno; Guay, David; Soultan, Al-Halifa; Gauthier, Marc A.. (2023). PEGylation of a Peptide-Based Amphiphilic Delivery Agent and Influence on Protein Delivery to Cells. BIOMACROMOLECULES. DOI: 10.1021/acs.biomac.3c00603 (http://dx.doi.org/10.1021/acs.biomac.3c00603)
Pastuszka, Adeline; Rousseau, Genevieve M.; Somerville, Vincent; Levesque, Sebastien; Fiset, Jean-Philippe; Goulet, Adeline; Doyon, Yannick; Moineau, Sylvain. (2023). Dairy phages escape CRISPR defence of Streptococcus thermophilus via the anti-CRISPR AcrIIA3. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY. DOI: 10.1016/j.ijfoodmicro.2023.110414 (http://dx.doi.org/10.1016/j.ijfoodmicro.2023.110414)
Naasani, Liliana Ivet Sous; Azevedoa, Jessica Gonsalves; Sevigny, Jean; de Oliveira, Tiago Franco; Maria-Engler, Silvya Stuchi; Wink, Marcia Rosangela. (2023). Epidermal melanocytes metabolize extracellular nucleotides by purinergic enzymes. BIOCHEMISTRY AND CELL BIOLOGY. DOI: 10.1139/bcb-2022-0058259 (http://dx.doi.org/10.1139/bcb-2022-0058259)
Sous Naasani, Liliana Ivet; Azevedo, Jessica Goncalves; Sevigny, Jean; de Oliveira, Tiago Franco; Maria-Engler, Silvya Stuchi; Wink, Marcia Rosangela. (2023). A study on solar radiation prediction using medium-range weather forecasts. BIOCHEMISTRY AND CELL BIOLOGY. DOI: 10.1139/bcb-2022-0058 (http://dx.doi.org/10.1139/bcb-2022-0058)
Nabeel-Shah, Syed; Garg, Jyoti; Ashraf, Kanwal; Jeyapala, Renu; Lee, Hyunmin; Petrova, Alexandra; Burns, James D.; Pu, Shuye; Zhang, Zhaolei; Greenblatt, Jack F.; Pearlman, Ronald E.; Lambert, Jean-Philippe; Fillingham, Jeffrey. (2023). Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation. EPIGENETICS & CHROMATIN. DOI: 10.1186/s13072-023-00484-9 (http://dx.doi.org/10.1186/s13072-023-00484-9)
Lemieux, Pascale; Bradley, David; Dube, Alexandre K.; Dionne, Ugo; Landry, Christian R.. (2023). Dissection of the role of a Src homology 3 domain in the evolution of binding preference of paralogous proteins. GENETICS. DOI: 10.1093/genetics/iyad175 (http://dx.doi.org/10.1093/genetics/iyad175)
Aube, Simon; Nielly-Thibault, Lou; Landry, Christian R.. (2023). Evolutionary trade-off and mutational bias could favor transcriptional over translational divergence within paralog pairs. PLOS GENETICS. DOI: 10.1371/journal.pgen.1010756 (http://dx.doi.org/10.1371/journal.pgen.1010756)
Lopez, Vittoria; Schuh, H. J. Maximilian; Mirza, Salahuddin; Vaassen, Victoria J.; Schmidt, Michael S.; Sylvester, Katharina; Idris, Riham M.; Renn, Christian; Schaekel, Laura; Pelletier, Julie; Sevigny, Jean; Naggi, Annamaria; Scheffler, Bjoern; Lee, Sang-Yong; Bendas, Gerd; Mueller, Christa E.. (2023). Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) - a promising target for the immunotherapy of cancer. FRONTIERS IN IMMUNOLOGY. DOI: 10.3389/fimmu.2023.1173634 (http://dx.doi.org/10.3389/fimmu.2023.1173634)
Rubenich, Dominique S.; de Souza, Priscila O.; Omizzollo, Natalia; Aubin, Mariana R.; Basso, Paulo J.; Silva, Luisa M.; da Silva, Eloisa M.; Teixeira, Fernanda C.; Gentil, Gabriela F. S.; Domagalski, Jordana L.; Cunha, Maico T.; Gadelha, Kerolainy A.; Diel, Leonardo F.; Gelsleichter, Nicolly E.; Rubenich, Aline S.; Lenz, Gabriela S.; de Abreu, Aline M.; Kroeff, Giselle M.; Paz, Ana H.; Visioli, Fernanda; Lamers, Marcelo L.; Wink, Marcia R.; Worm, Paulo V.; Araujo, Anelise B.; Sevigny, Jean; Camara, Niels O. S.; Ludwig, Nils; Braganhol, Elizandra. (2023). Tumor-neutrophil crosstalk promotes in vitro and in vivo glioblastoma progression. FRONTIERS IN IMMUNOLOGY. DOI: 10.3389/fimmu.2023.1183465 (http://dx.doi.org/10.3389/fimmu.2023.1183465)
Gashti, Anahita Bakhshizadeh; Chahal, Parminder S.; Gaillet, Bruno; Garnier, Alain. (2023). Purification of recombinant vesicular stomatitis virus-based HIV vaccine candidate. VACCINE. DOI: 10.1016/j.vaccine.2023.02.058 (http://dx.doi.org/10.1016/j.vaccine.2023.02.058)
Plante, Samuel R.; Moon, Kyung-Mee; Lemieux, Pascale; Foster, Leonard; Landry, Christian. (2023). Breaking spore dormancy in budding yeast transforms the cytoplasm and the solubility of the proteome. PLOS BIOLOGY. DOI: 10.1371/journal.pbio.3002042 (http://dx.doi.org/10.1371/journal.pbio.3002042)
O'Sullivan, Julia; Kothari, Charu; Caron, Marie-Christine; Gagne, Jean-Philippe; Jin, Zhigang; Nonfoux, Louis; Beneyton, Adele; Coulombe, Yan; Thomas, Melissa; Atalay, Nurgul; Meng, X. Wei; Milano, Larissa; Jean, Dominique; Boisvert, Francois-Michel; Kaufmann, Scott H.; Hendzel, Michael J.; Masson, Jean-Yves; Poirier, Guy G.. (2023). ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkad791 (http://dx.doi.org/10.1093/nar/gkad791)
Laspata, Natalie; Kaur, Parminder; Mersaoui, Sofiane Yacine; Muoio, Daniela; Liu, Zhiyan Silvia; Bannister, Maxwell Henry; Nguyen, Hai Dang; Curry, Caroline; Pascal, John M.; Poirier, Guy G.; Wang, Hong; Masson, Jean-Yves; Fouquerel, Elise. (2023). PARP1 associates with R-loops to promote their resolution and genome stability. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkad066 (http://dx.doi.org/10.1093/nar/gkad066)
Jalsic, Lovro; Lytvyn, Viktoria; Elahi, Seyyed Mehdy; Hrapovic, Sabahudin; Nassoury, Nasha; Chahal, Parminder Singh; Gaillet, Bruno; Gilbert, Renald. (2023). Inducible HEK293 AAV packaging cell lines expressing Rep proteins. MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT. DOI: 10.1016/j.omtm.2023.07.002 (http://dx.doi.org/10.1016/j.omtm.2023.07.002)
Hosseini, Nava; Paquet, Valerie E.; Marcoux, Pierre-Etienne; Alain, Charles-Antoine; Paquet, Maude F.; Moineau, Sylvain; Charette, Steve J.. (2023). MQM1, a bacteriophage infecting strains of Aeromonas salmonicida subspecies salmonicida carrying Prophage 3. VIRUS RESEARCH. DOI: 10.1016/j.virusres.2023.199165 (http://dx.doi.org/10.1016/j.virusres.2023.199165)
Becht, Dustin C.; Klein, Brianna J.; Kanai, Akinori; Jang, Suk Min; Cox, Khan L.; Zhou, Bing-Rui; Phanor, Sabrina K.; Zhang, Yi; Chen, Ruo-Wen; Ebmeier, Christopher C.; Lachance, Catherine; Galloy, Maxime; Fradet-Turcotte, Amelie; Bulyk, Martha L.; Bai, Yawen; Poirier, Michael G.; Cote, Jacques; Yokoyama, Akihiko; Kutateladze, Tatiana G.. (2023). MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-023-36368-5 (http://dx.doi.org/10.1038/s41467-023-36368-5)
Philippe, Cecile; Cornuault, Jeffrey K.; de Melo, Alessandra G.; Morin-Pelchat, Rachel; Jolicoeur, Alice P.; Moineau, Sylvain. (2023). The never-ending battle between lactic acid bacteria and their phages. FEMS MICROBIOLOGY REVIEWS. DOI: 10.1093/femsre/fuad035 (http://dx.doi.org/10.1093/femsre/fuad035)
Campbell, Zoe A.; Njiru, Nelly; Mhone, Amos Lucky; Makumi, Angela; Moineau, Sylvain; Svitek, Nicholas. (2023). Gender-Responsive Design of Bacteriophage Products to Enhance Adoption by Chicken Keepers in Kenya. VIRUSES-BASEL. DOI: 10.3390/v15030746 (http://dx.doi.org/10.3390/v15030746)
Teyssier, Valentine; Chartier, Francois; St-Onge, Gabrielle; Lessard, Frederic; Bisson, Nicolas. (2023). Mechanisms regulating the specificity of NCK1/2 adaptor proteins. JOURNAL OF BIOLOGICAL CHEMISTRY. DOI: 10.1016/j.jbc.2023.103983 (http://dx.doi.org/10.1016/j.jbc.2023.103983)
Peris, David; Ubbelohde, Emily J.; Kuang, Meihua Christina; Kominek, Jacek; Langdon, Quinn K.; Adams, Marie; Koshalek, Justin A.; Hulfachor, Amanda Beth; Opulente, Dana A.; Hall, David J.; Hyma, Katie; Fay, Justin C.; Leducq, Jean-Baptiste; Charron, Guillaume; Landry, Christian R.; Libkind, Diego; Goncalves, Carla; Goncalves, Paula; Sampaio, Jose Paulo; Wang, Qi-Ming; Bai, Feng-Yan; Wrobel, Russel L.; Hittinger, Chris Todd. (2023). Macroevolutionary diversity of traits and genomes in the model yeast genus Saccharomyces. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-023-36139-2 (http://dx.doi.org/10.1038/s41467-023-36139-2)
Dash, Shantoshini; Farnos, Omar; Yang, Zeyu; Perumal, Ayyappasamy Sudalaiyadum; Fulber, Julia Puppin Chaves; Venereo-Sanchez, Alina; Leclerc, Denis; Kamen, Amine A.. (2023). A rapid procedure to generate stably transfected HEK293 suspension cells for recombinant protein manufacturing: Yield improvements, bioreactor production and downstream processing. PROTEIN EXPRESSION AND PURIFICATION. DOI: 10.1016/j.pep.2023.106295 (http://dx.doi.org/10.1016/j.pep.2023.106295)
Shah, Shiraz A.; Deng, Ling; Thorsen, Jonathan; Pedersen, Anders G.; Dion, Moira B.; Castro-Mejia, Josue L.; Silins, Ronalds; Romme, Fie O.; Sausset, Romain; Jessen, Leon E.; Ndela, Eric Olo; Hjelmso, Mathis; Rasmussen, Morten A.; Redgwell, Tamsin A.; Rodriguez, Cristina Leal; Vestergaard, Gisle; Zhang, Yichang; Chawes, Bo; Bonnelykke, Klaus; Sorensen, Soren J.; Bisgaard, Hans; Enault, Francois; Stokholm, Jakob; Moineau, Sylvain; Petit, Marie-Agnes; Nielsen, Dennis S.. (2023). Expanding known viral diversity in the healthy infant gut. NATURE MICROBIOLOGY. DOI: 10.1038/s41564-023-01345-7 (http://dx.doi.org/10.1038/s41564-023-01345-7)
Agbo, Lynda; Loehr, Jeremy; Tchara, Pata-Eting Kougnassoukou; Lambert, Jean-Philippe. (2023). Characterization of the Functional Interplay between the BRD7 and BRD9 Homologues in mSWI/SNF Complexes. JOURNAL OF PROTEOME RESEARCH. DOI: 10.1021/acs.jproteome.2c00464 (http://dx.doi.org/10.1021/acs.jproteome.2c00464)
de Melo, Alessandra G.; Lemay, Marie-Laurence; Moineau, Sylvain. (2023). The impact of Brevibacterium aurantiacum virulent phages on the production of smear surface-ripened cheeses. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY. DOI: 10.1016/j.ijfoodmicro.2023.110252 (http://dx.doi.org/10.1016/j.ijfoodmicro.2023.110252)
Jalil, Saquib; Ullah, Saif; Zaraei, Seyed-Omar; Sbenati, Rawan M.; Shahin, Afnan I.; AlKubaisi, Bilal O.; Pelletier, Julie; Sevigny, Jean; Al-Tel, Taleb H.; Iqbal, Jamshed; El-Gamal, Mohammed I.. (2023). Synthesis and biological evaluation of sulfamate derivatives as inhibitors of carbonic anhydrases II and IX. MEDICINAL CHEMISTRY RESEARCH. DOI: 10.1007/s00044-023-03043-9 (http://dx.doi.org/10.1007/s00044-023-03043-9)
Ghio, Sergio Cortez; Barbier, Martin A.; Doucet, Emilie J.; Debbah, Imad; Safoine, Meryem; Le-Bel, Gaetan; Cartier, Andreanne; Jolibois, Emilie; Morissette, Amelie; Larouche, Danielle; Fradette, Julie; Guerin, Sylvain L.; Garnier, Alain; Germain, Lucie. (2023). A Newly Developed Chemically Defined Serum-Free Medium Suitable for Human Primary Keratinocyte Culture and Tissue Engineering Applications. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms24031821 (http://dx.doi.org/10.3390/ijms24031821)
Niyonambaza, Shimwe Dominique; Lachance, Gabriel P.; Boisselier, Elodie; Boukadoum, Mounir; Miled, Amine. (2023). Concept of a Crossed Czerny-Turner Spectrometer With an Integrated Automatic Sampling System for Biodetection Using Ultrastable Gold Nanoparticles. IEEE SENSORS JOURNAL. DOI: 10.1109/JSEN.2023.3279649 (http://dx.doi.org/10.1109/JSEN.2023.3279649)
Loiseau, Alexis; Raiche-Marcoux, Gabrielle; Maranda, Cloe; Bertrand, Nicolas; Boisselier, Elodie. (2023). Animal Models in Eye Research: Focus on Corneal Pathologies. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms242316661 (http://dx.doi.org/10.3390/ijms242316661)
Rasmussen, Torben Solbeck; Koefoed, Anna Kirstine; Deng, Ling; Muhammed, Musemma K.; Rousseau, Genevieve M.; Kot, Witold; Sprotte, Sabrina; Neve, Horst; Franz, Charles M. A. P.; Hansen, Axel Kornerup; Vogensen, Finn Kvist; Moineau, Sylvain; Nielsen, Dennis Sandris. (2023). CRISPR-Cas provides limited phage immunity to a prevalent gut bacterium in gnotobiotic mice. ISME JOURNAL. DOI: 10.1038/s41396-023-01358-4 (http://dx.doi.org/10.1038/s41396-023-01358-4)
Bi, Chunyang; Schaekel, Laura; Mirza, Salahuddin; Sylvester, Katharina; Pelletier, Julie; Lee, Sang -Yong; Pillaiyar, Thanigaimalai; Sevigny, Jean; Mueller, Christa E.. (2023). Synthesis and structure-activity relationships of ticlopidine derivatives and analogs as inhibitors of ectonucleotidase CD39. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2023.106460 (http://dx.doi.org/10.1016/j.bioorg.2023.106460)
Favre, Julie; Roy, Charlotte; Guihot, Anne-Laure; Drouin, Annick; Laprise, Manon; Gillis, Marc-Antoine; Robson, Simon C.; Thorin, Eric; Sevigny, Jean; Henrion, Daniel; Kauffenstein, Gilles. (2023). NTPDase1/CD39 Ectonucleotidase Is Necessary for Normal Arterial Diameter Adaptation to Flow. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms242015038 (http://dx.doi.org/10.3390/ijms242015038)
Hosseini, S. Nazila; Akram, Mohammad Makhdoumi; Das, Partha Sarati; Lazarjan, Vahid Khojasteh; Tremblay, Denise M.; Moineau, Sylvain; Messaddeq, Younes; Gosselin, Benoit. (2023). Multimodal CMOS Biosensor for Microbial Growth Monitoring. IEEE SENSORS JOURNAL. DOI: 10.1109/JSEN.2023.3272620 (http://dx.doi.org/10.1109/JSEN.2023.3272620)
Younus, Hafiza Amna; Saeed, Muhammad; Mahmood, Abid; Jadoon, Muhammad Siraj Khan; Hameed, Abdul; Asari, Asnuzilawati; Mohamad, Habsah; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed; al-Rashida, Mariya. (2023). Exploring chromone sulfonamides and sulfonylhydrazones as highly selective ectonucleotidase inhibitors: Synthesis, biological evaluation and in silico study. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2023.106450 (http://dx.doi.org/10.1016/j.bioorg.2023.106450)
Ullah, Saif; Hamid, Kiran; Batool, Amna; Pelletier, Julie; Sevigny, Jean; Khan, Abdul Rehman; Langer, Peter; Iqbal, Jamshed. (2023). Synthesis of new sulphonate derivatives containing adamantane and 4-chlorophenyl moieties as nucleotide pyrophosphatase/phosphodiesterase-1 and-3 inhibitors. JOURNAL OF MOLECULAR STRUCTURE. DOI: 10.1016/j.molstruc.2022.134494 (http://dx.doi.org/10.1016/j.molstruc.2022.134494)
2022
Tremblay, Thomas; Alcee, Jessica B.; Giguere, Denis. (2022). Protecting-group-free synthesis of clevudine (l-FMAU), a treatment of the hepatitis B virus. ORGANIC & BIOMOLECULAR CHEMISTRY. DOI: 10.1039/d2ob01814d (http://dx.doi.org/10.1039/d2ob01814d)
Fortier, David; Seguin, Jean-Christophe; Voyer, Normand. (2022). Characterization of the Volatilome of Tuber canaliculatum Harvested in Quebec, Canada. ACS OMEGA. DOI: 10.1021/acsomega.2c0287729038ACS (http://dx.doi.org/10.1021/acsomega.2c0287729038ACS)
Despres, Philippe C.; Cisneros, Angel F.; Alexander, Emilie Mm; Sonigara, Ria; Gagne-Thivierge, Cynthia; Dube, Alexandre K.; Landry, Christian R.. (2022). Asymmetrical dose responses shape the evolutionary trade-off between antifungal resistance and nutrient use. NATURE ECOLOGY & EVOLUTION. DOI: 10.1038/s41559-022-01846-4 (http://dx.doi.org/10.1038/s41559-022-01846-4)
Fortier, David; Seguin, Jean-Christophe; Voyer, Normand. (2022). Characterization of the Volatilome of Tuber canaliculatum Harvested in Quebec, Canada. ACS OMEGA. DOI: 10.1021/acsomega.2c02877 (http://dx.doi.org/10.1021/acsomega.2c02877)
Lessard, Olivier; Laine, Danny; Fecteau, Charles-Emile; Johnson, Paul A.; Giguere, Denis. (2022). Fundamental curiosity of multivicinal inter-halide stereocenters. ORGANIC CHEMISTRY FRONTIERS. DOI: 10.1039/d2qo01433e (http://dx.doi.org/10.1039/d2qo01433e)
Guillemet, Martin; Chabas, Helene; Nicot, Antoine; Gatchich, Francois; Ortega-Abboud, Enrique; Buus, Cornelia; Hindhede, Lotte; Rousseau, Genevieve M.; Bataillon, Thomas; Moineau, Sylvain; Gandon, Sylvain. (2022). Competition and coevolution drive the evolution and the diversification of CRISPR immunity. NATURE ECOLOGY & EVOLUTION. DOI: 10.1038/s41559-022-01841-9 (http://dx.doi.org/10.1038/s41559-022-01841-9)
Ullah, Saif; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2022). Synthesis and Biological Evaluation of Arylamide Sulphonate Derivatives as Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 and-3 Inhibitors. ACS OMEGA. DOI: 10.1021/acsomega.2c03473 (http://dx.doi.org/10.1021/acsomega.2c03473)
Soltani, Samira; Zirah, Severine; Rebuffat, Sylvie; Couture, Frederic; Boutin, Yvan; Biron, Eric; Subirade, Muriel; Fliss, Ismail. (2022). Gastrointestinal Stability and Cytotoxicity of Bacteriocins From Gram-Positive and Gram-Negative Bacteria: A Comparative in vitro Study. FRONTIERS IN MICROBIOLOGY. DOI: 10.3389/fmicb.2021.780355 (http://dx.doi.org/10.3389/fmicb.2021.780355)
Prifti, Diogjena Katerina; Lauzier, Annie; Elowe, Sabine. (2022). A commercial ARHGEF17/TEM4 antibody cross-reacts with Nuclear Mitotic Apparatus protein 1 (NuMA). PLOS ONE. DOI: 10.1371/journal.pone.0268848 (http://dx.doi.org/10.1371/journal.pone.0268848)
Soulard, Guillaume; Lachance, Gabriel P.; Boisselier, Elodie; Boukadoum, Mounir; Miled, Amine. (2022). RISC-V Based Processor Architecture for an Embedded Visible Light Spectrophotometer. 2022 IEEE CANADIAN CONFERENCE ON ELECTRICAL AND COMPUTER ENGINEERING (CCECE). DOI: 10.1109/CCECE49351.2022.9918259 (http://dx.doi.org/10.1109/CCECE49351.2022.9918259)
Levesque, Sebastien; Mayorga, Diana; Fiset, Jean-Philippe; Goupil, Claudia; Duringer, Alexis; Loiselle, Andreanne; Bouchard, Eva; Agudelo, Daniel; Doyon, Yannick. (2022). Marker-free co-selection for successive rounds of prime editing in human cells. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-022-33669-z (http://dx.doi.org/10.1038/s41467-022-33669-z)
Xavier, Andre da Silva; de Melo, Alessandra G.; Hendrich, Connor G.; Tremblay, Denise M.; Rousseau, Genevieve M.; Plante, Pier-Luc; Forest, Katrina T.; Alfenas-Zerbini, Poliane; Allen, Caitilyn; Moineau, Sylvain. (2022). In through the Out Door: A Functional Virulence Factor Secretion System Is Necessary for Phage Infection in Ralstonia solanacearum. MBIO. DOI: 10.1128/mbio.01475-22 (http://dx.doi.org/10.1128/mbio.01475-22)
Gunathilake, K. M. Damitha; Tremblay, Denise M.; Plante, Pier-Luc; Jensen, Ellen C.; Nickerson, Kenneth W.; Moineau, Sylvain. (2022). Genome Sequence of SN1, a Bacteriophage That Infects Sphaerotilus natans and Pseudomonas aeruginosa. MICROBIOLOGY RESOURCE ANNOUNCEMENTS. DOI: 10.1128/mra.00478-22 (http://dx.doi.org/10.1128/mra.00478-22)
Soltani, Samira; Biron, Eric; Ben Said, Laila; Subirade, Muriel; Fliss, Ismail. (2022). Bacteriocin-Based Synergetic Consortia: a Promising Strategy to Enhance Antimicrobial Activity and Broaden the Spectrum of Inhibition. MICROBIOLOGY SPECTRUM. DOI: 10.1128/spectrum.00406-21 (http://dx.doi.org/10.1128/spectrum.00406-21)
Bertrand, Xavier; Paquin, Pascal; Chabaud, Laurent; Paquin, Jean-Francois. (2022). Hydrohalogenation of Unactivated Alkenes Using a Methanesulfonic Acid/Halide Salt Combination. SYNTHESIS-STUTTGART. DOI: 10.1055/s-0040-1719856 (http://dx.doi.org/10.1055/s-0040-1719856)
Kejzar, Nejc; Laanto, Elina; Rissanen, Ilona; Abrishami, Vahid; Selvaraj, Muniyandi; Moineau, Sylvain; Ravantti, Janne; Sundberg, Lotta-Riina; Huiskonen, Juha T.. (2022). Cryo-EM structure of ssDNA bacteriophage ΦCjT23 provides insight into early virus evolution. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-022-35123-6 (http://dx.doi.org/10.1038/s41467-022-35123-6)
Jung, Young-Hwan; Shah, Qasim; Lewicki, Sarah A.; Pramanik, Asmita; Gopinatth, Varun; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed; Jacobson, Kenneth A.. (2022). Synthesis and pharmacological characterization of multiply substituted 2H-chromene derivatives as P2Y6 receptor antagonists. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. DOI: 10.1016/j.bmcl.2022.128981 (http://dx.doi.org/10.1016/j.bmcl.2022.128981)
Birepinte, Melodie; Champagne, Pier Alexandre; Paquin, Jean-Francois. (2022). Photoinitiated anti-Hydropentafluorosulfanylation of Terminal Alkynes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. DOI: 10.1002/anie.202112575 (http://dx.doi.org/10.1002/anie.202112575)
dos Santos, Alexsandro; Ouellete, Genevieve; Diorio, Caroline; Elowe, Sabine; Durocher, Francine. (2022). Knockdown of CKAP2 Inhibits Proliferation, Migration, and Aggregate Formation in Aggressive Breast Cancer. CANCERS. DOI: 10.3390/cancers14153759 (http://dx.doi.org/10.3390/cancers14153759)
Kiseleva, Mariia; Omar, Mahmoud M.; Boisselier, Elodie; Selivanova, Svetlana, V; Fortin, Marc-Andre. (2022). A Three-Dimensional Printable Hydrogel Formulation for the Local Delivery of Therapeutic Nanoparticles to Cervical Cancer. ACS BIOMATERIALS SCIENCE & ENGINEERING. DOI: 10.1021/acsbiomaterials.1c01399 (http://dx.doi.org/10.1021/acsbiomaterials.1c01399)
Salem, Mabrouka; Lecka, Joanna; Pelletier, Julie; Marconato, Danielle Gomes; Dumas, Aline; Vallieres, Luc; Brochu, Gaetan; Robaye, Bernard; Jobin, Christian; Sevigny, Jean. (2022). NTPDase8 protects mice from intestinal inflammation by limiting P2Y6 receptor activation: identification of a new pathway of inflammation for the potential treatment of IBD. GUT. DOI: 10.1136/gutjnl-2020-320937 (http://dx.doi.org/10.1136/gutjnl-2020-320937)
Lachance, Gabriel P.; Boisselier, Elodie; Boukadoum, Mounir; Miled, Amine. (2022). Towards an advanced neurotechnological system: colorimetric sensing with a novel grism-based spectrometer, functionalized gold nanoparticles and a heterogeneous embedded system. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES. DOI: 10.1098/rsta.2021.0016 (http://dx.doi.org/10.1098/rsta.2021.0016)
Rasouli, Hannaneh; Iliuta, Ion; Bougie, Francis; Garnier, Alain; Iliuta, Maria C.. (2022). Enhanced CO2 capture in packed-bed column bioreactors with immobilized carbonic anhydrase. CHEMICAL ENGINEERING JOURNAL. DOI: 10.1016/j.cej.2021.134029 (http://dx.doi.org/10.1016/j.cej.2021.134029)
Lu, Phoebe Y. T.; Kirlin, Alyssa C.; Aristizabal, Maria J.; Brewis, Hilary T.; Levesque, Nancy; Setiaputra, Dheva T.; Avvakumov, Nikita; Benschop, Joris J.; Koerkamp, Marian Groot; Holstege, Frank C. P.; Krogan, Nevan J.; Yip, Calvin K.; Cote, Jacques; Kobor, Michael S.. (2022). A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans. GENETICS. DOI: 10.1093/genetics/iyac136 (http://dx.doi.org/10.1093/genetics/iyac136)
Rasouli, Hannaneh; Iliuta, Ion; Bougie, Francis; Garnier, Alain; Iliuta, Maria C.. (2022). Hybrid enzymatic CO2 capture process in intensified flat sheet membrane contactors with immobilized carbonic anhydrase. SEPARATION AND PURIFICATION TECHNOLOGY. DOI: 10.1016/j.seppur.2022.120505 (http://dx.doi.org/10.1016/j.seppur.2022.120505)
Soltani, Samira; Boutin, Yvan; Couture, Frederic; Biron, Eric; Subirade, Muriel; Fliss, Ismail. (2022). In vitro assessment of skin sensitization, irritability and toxicity of bacteriocins and reuterin for possible topical applications. SCIENTIFIC REPORTS. DOI: 10.1038/s41598-022-08441-4 (http://dx.doi.org/10.1038/s41598-022-08441-4)
Lashgari, Anahita; Tchara, Pata-Eting Kougnassoukou; Lambert, Jean-Philippe; Cote, Jacques. (2022). New insights into the DNA repair pathway choice with NuA4/TIP60. DNA REPAIR. DOI: 10.1016/j.dnarep.2022.103315 (http://dx.doi.org/10.1016/j.dnarep.2022.103315)
Dikpati, Amrita; Gaudreault, Nicolas; Chenard, Valerie; Grenier, Philippe; Boisselier, Elodie; Bertrand, Nicolas. (2022). Size Exclusion of Radioactive Polymers (SERP) informs on the biodegradation of trimethyl chitosan and biodegradable polymer nanoparticles in vitro and in vivo. JOURNAL OF CONTROLLED RELEASE. DOI: 10.1016/j.jconrel.2022.04.009 (http://dx.doi.org/10.1016/j.jconrel.2022.04.009)
Berube, Christopher; Borgia, Alexandre; Voyer, Normand. (2022). Total synthesis of the macrocyclic peptide stylopeptide II using oxime resin. TETRAHEDRON LETTERS. DOI: 10.1016/j.tetlet.2022.153677 (http://dx.doi.org/10.1016/j.tetlet.2022.153677)
Vincent, Thierry; Gaillet, Bruno; Garnier, Alain. (2022). Optimization of operation conditions for improved cytochrome P450BM3 enzymatic reaction yield. CANADIAN JOURNAL OF CHEMICAL ENGINEERING. DOI: 10.1002/cjce.24232 (http://dx.doi.org/10.1002/cjce.24232)
Hamoudi, Chakib; Zhao, Chenqi; Abderrazak, Amna; Salem, Mabrouka; Fortin, Paul R.; Sevigny, Jean; Aoudjit, Fawzi. (2022). The Purinergic Receptor P2X4 Promotes Th17 Activation and the Development of Arthritis. JOURNAL OF IMMUNOLOGY. DOI: 10.4049/jimmunol.2100550 (http://dx.doi.org/10.4049/jimmunol.2100550)
Bieluszewski, Tomasz; Sura, Weronika; Dziegielewski, Wojciech; Bieluszewska, Anna; Lachance, Catherine; Kabza, Michal; Szymanska-Lejman, Maja; Abram, Mateusz; Wlodzimierz, Piotr; De Winne, Nancy; De Jaeger, Geert; Sadowski, Jan; Cote, Jacques; Ziolkowski, Piotr A.. (2022). NuA4 and H2A.Z control environmental responses and autotrophic growth in Arabidopsis. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-021-27882-5 (http://dx.doi.org/10.1038/s41467-021-27882-5)
Cashman-Kadri, Samuel; Lague, Patrick; Fliss, Ismail; Beaulieu, Lucie. (2022). Determination of the Relationships between the Chemical Structure and Antimicrobial Activity of a GAPDH-Related Fish Antimicrobial Peptide and Analogs Thereof. ANTIBIOTICS-BASEL. DOI: 10.3390/antibiotics11030297 (http://dx.doi.org/10.3390/antibiotics11030297)
Rahman, Md Ramim Tanver; Fliss, Ismail; Biron, Eric. (2022). Insights in the Development and Uses of Alternatives to Antibiotic Growth Promoters in Poultry and Swine Production. ANTIBIOTICS-BASEL. DOI: 10.3390/antibiotics11060766 (http://dx.doi.org/10.3390/antibiotics11060766)
Gauthier, Raphael; Tzouras, Nikolaos, V; Zhang, Ziyun; Bedard, Sandrine; Saab, Marina; Falivene, Laura; Van Hecke, Kristof; Cavallo, Luigi; Nolan, Steven P.; Paquin, Jean-Francois. (2022). Gold N-Heterocyclic Carbene Catalysts for the Hydrofluorination of Alkynes Using Hydrofluoric Acid: Reaction Scope, Mechanistic Studies and the Tracking of Elusive Intermediates. CHEMISTRY-A EUROPEAN JOURNAL. DOI: 10.1002/chem.202103886 (http://dx.doi.org/10.1002/chem.202103886)
Olivera-Ugarte, Santa-Mariela; Bolduc, Marilene; Laliberte-Gagne, Marie-Eve; Blanchette, Lea-Jeanne; Garneau, Caroline; Fillion, Maude; Savard, Pierre; Dubuc, Isabelle; Flamand, Louis; Farnos, Omar; Xu, Xingge; Kamen, Amine; Gilbert, Megan; Rabezanahary, Henintsoa; Scarrone, Martina; Couture, Christian; Baz, Mariana; Leclerc, Denis. (2022). A nanoparticle-based COVID-19 vaccine candidate elicits broad neutralizing antibodies and protects against SARS-CoV-2 infection. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE. DOI: 10.1016/j.nano.2022.102584 (http://dx.doi.org/10.1016/j.nano.2022.102584)
Lachance, Gabriel P.; Boisselier, Elodie; Boukadoum, Mounir; Miled, Amine. (2022). Molecular Sensing System Based on Multi-Technologies Architecture. OPTICAL DIAGNOSTICS AND SENSING XXII: TOWARD POINT-OF-CARE DIAGNOSTICS. DOI: 10.1117/12.2610075 (http://dx.doi.org/10.1117/12.2610075)
Boccacci, Yelena; Margaillan, Guillaume; Dumont, Nellie; Dube, Pascal; Doyon, Yannick; Laganiere, Josee. (2022). Ex Vivo CRISPR-Based Sickle Cell Modeling. BLOOD. DOI: 10.1182/blood-2022-169327 (http://dx.doi.org/10.1182/blood-2022-169327)
Philippe, Cecile; Morency, Carlee; Plante, Pier-Luc; Zufferey, Edwige; Achigar, Rodrigo; Tremblay, Denise M.; Rousseau, Genevieve M.; Goulet, Adeline; Moineau, Sylvain. (2022). A truncated anti-CRISPR protein prevents spacer acquisition but not interference. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-022-30310-x (http://dx.doi.org/10.1038/s41467-022-30310-x)
Dionne, Ugo; Percival, Lily J.; Chartier, Francois J. M.; Landry, Christian R.; Bisson, Nicolas. (2022). SRC homology 3 domains: multifaceted binding modules. TRENDS IN BIOCHEMICAL SCIENCES. DOI: 10.1016/j.tibs.2022.04.005 (http://dx.doi.org/10.1016/j.tibs.2022.04.005)
Arif, M.; Shabir, G.; Ejaz, S. A.; Saeed, A.; Khan, S. U.; Lecka, J.; Sevigny, J.; Iqbal, J.. (2022). Diacylhydrazine Derivatives of 2-(5-(Pyridin-3-yl)-2H-Tetrazol-2-yl)Acetohydrazide and 2-(5-(Pyridin-4-yl)-2H-Tetrazol-2-yl)Acetohydrazide as Potential Inhibitors of Nucleotide Pyrophosphatase. RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY. DOI: 10.1134/S1068162022050053 (http://dx.doi.org/10.1134/S1068162022050053)
Devoucoux, Maeva; Fort, Victoire; Khelifi, Gabriel; Xu, Joshua; Alerasool, Nader; Galloy, Maxime; Wong, Nicholas; Bourriquen, Gaelle; Fradet-Turcotte, Amelie; Taipale, Mikko; Hope, Kristin; Hussein, Samer M., I; Cote, Jacques. (2022). Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes. CELL REPORTS. DOI: 10.1016/j.celrep.2022.110947 (http://dx.doi.org/10.1016/j.celrep.2022.110947)
Thanh Tung Lai; Thi Thanh Ha Pham; van Lingen, Marijn; Desaulniers, Gabrielle; Njamen, Guy; Tolnai, Balazs; Jabrane, Tarik; Moineau, Sylvain; Barnabe, Simon. (2022). Development of Antimicrobial Paper Coatings Containing Bacteriophages and Silver Nanoparticles for Control of Foodborne Pathogens. VIRUSES-BASEL. DOI: 10.3390/v14112478 (http://dx.doi.org/10.3390/v14112478)
Banerjee, Sara L.; Lessard, Frederic; Chartier, Francois J. M.; Jacquet, Kevin; Osornio-Hernandez, Ana, I; Teyssier, Valentine; Ghani, Karim; Lavoie, Noemie; Lavoie, Josee N.; Caruso, Manuel; Laprise, Patrick; Elowe, Sabine; Lambert, Jean-Philippe; Bisson, Nicolas. (2022). EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks. CELL REPORTS. DOI: 10.1016/j.celrep.2022.111031 (http://dx.doi.org/10.1016/j.celrep.2022.111031)
Lachance, Alexandre; Hebert, Melanie; Hebert, Marc; Salesse, Christian; Bourgault, Serge; Dirani, Ali. (2022). Analysis of Molecular Genetic Testing Referrals for Inherited Retinal Dystrophies in a Quebec Tertiary Care Center Over a Decade. CLINICAL OPHTHALMOLOGY. DOI: 10.2147/OPTH.S346103 (http://dx.doi.org/10.2147/OPTH.S346103)
Evans-Yamamoto, Daniel; Rouleau, Francois D.; Nanda, Piyush; Makanae, Koji; Liu, Yin; Despres, Philippe C.; Matsuo, Hitoshi; Seki, Motoaki; Dube, Alexandre K.; Ascencio, Diana; Yachie, Nozomu; Landry, Christian R.. (2022). Barcode fusion genetics-protein-fragment complementation assay (BFG-PCA): tools and resources that expand the potential for binary protein interaction discovery. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkac045 (http://dx.doi.org/10.1093/nar/gkac045)
Vincent, Thierry; Gaillet, Bruno; Garnier, Alain. (2022). Oleic acid based experimental evolution of Bacillus megaterium yielding an enhanced P450 BM3 variant. BMC BIOTECHNOLOGY. DOI: 10.1186/s12896-022-00750-w (http://dx.doi.org/10.1186/s12896-022-00750-w)
Millette, Marc-Antoine; Roy, Sarah; Salesse, Christian. (2022). Farnesylation and lipid unsaturation are critical for the membrane binding of the C-terminal segment of G-Protein Receptor Kinase 1. COLLOIDS AND SURFACES B-BIOINTERFACES. DOI: 10.1016/j.colsurfb.2021.112315 (http://dx.doi.org/10.1016/j.colsurfb.2021.112315)
Lelong, Emeline I. J.; Khelifi, Gabriel; Adjibade, Pauline; Joncas, France-Helene; St-Sauveur, Valerie Grenier; Paquette, Virginie; Gris, Typhaine; Zoubeidi, Amina; Audet-Walsh, Etienne; Lambert, Jean-Philippe; Toren, Paul; Mazroui, Rachid; Hussein, Samer M. I.. (2022). Prostate cancer resistance leads to a global deregulation of translation factors and unconventional translation. NAR CANCER. DOI: 10.1093/narcan/zcac034 (http://dx.doi.org/10.1093/narcan/zcac034)
Elowe, Sabine; Bolanos-Garcia, Victor M.. (2022). The spindle checkpoint proteins BUB1 and BUBR1: (SLiM)ming down to the basics. TRENDS IN BIOCHEMICAL SCIENCES. DOI: 10.1016/j.tibs.2022.01.004 (http://dx.doi.org/10.1016/j.tibs.2022.01.004)
Oechslin, Frank; Zhu, Xiaojun; Dion, Moira B.; Shi, Rong; Moineau, Sylvain. (2022). Phage endolysins are adapted to specific hosts and are evolutionarily dynamic. PLOS BIOLOGY. DOI: 10.1371/journal.pbio.3001740 (http://dx.doi.org/10.1371/journal.pbio.3001740)
Alvarez, Cora L.; Chene, Arnaud; Semblat, Jean-Philippe; Gamain, Benoit; Lapoumeroulie, Claudine; Fader, Claudio M.; Hattab, Claude; Sevigny, Jean; Denis, Maria Florencia Leal; Lauri, Natalia; Ostuni, Mariano A.; Schwarzbaum, Pablo J.. (2022). Homeostasis of extracellular ATP in uninfected RBCs from a Plasmodium falciparum culture and derived microparticles. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. DOI: 10.1016/j.bbamem.2022.183980 (http://dx.doi.org/10.1016/j.bbamem.2022.183980)
Abbas, Sadia; Afzal, Saira; Nadeem, Humaira; Hussain, Dilawar; Langer, Peter; Sevigny, Jean; Ashraf, Zaman; Iqbal, Jamshed. (2022). Synthesis, characterization and biological evaluation of thiadiazole amide derivatives as nucleoside triphosphate diphosphohydrolases (NTPDases) inhibitors. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2021.105456 (http://dx.doi.org/10.1016/j.bioorg.2021.105456)
Schaekel, Laura; Mirza, Salahuddin; Winzer, Riekje; Lopez, Vittoria; Idris, Riham; Al-Hroub, Haneen; Pelletier, Julie; Sevigny, Jean; Tolosa, Eva; Mueller, Christa E.. (2022). Protein kinase inhibitor ceritinib blocks ectonucleotidase CD39-a promising target for cancer immunotherapy. JOURNAL FOR IMMUNOTHERAPY OF CANCER. DOI: 10.1136/jitc-2022-004660 (http://dx.doi.org/10.1136/jitc-2022-004660)
Vann, Kendra R.; Acharya, Arpan; Jang, Suk Min; Lachance, Catherine; Zandian, Mohamad; Holt, Tina A.; Smith, Audrey L.; Pandey, Kabita; Durden, Donald L.; El-Gamal, Dalia; Cote, Jacques; Byrareddy, Siddappa N.; Kutateladze, Tatiana G.. (2022). Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection. STRUCTURE. DOI: 10.1016/j.str.2022.05.020 (http://dx.doi.org/10.1016/j.str.2022.05.020)
Martin, Claire E.; Phippen, Noah J.; Chahi, Ava Keyvani; Tilak, Manali; Banerjee, Sara L.; Lu, Peihua; New, Laura A.; Williamson, Casey R.; Platt, Mathew J.; Simpson, Jeremy A.; Krendel, Mira; Bisson, Nicolas; Gingras, Anne-Claude; Jones, Nina. (2022). Complementary Nck1/2 Signaling in Podocytes Controls α Actinin-4-Mediated Actin Organization, Adhesion, and Basement Membrane Composition. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. DOI: 10.1681/ASN.2021101343 (http://dx.doi.org/10.1681/ASN.2021101343)
Begum, Zahra; Ullah, Saif; Akram, Muhammad; Uzair, Muhammad; Ullah, Farman; Ahsanullah; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed; Hassan, Abbas. (2022). Identification of thienopyrimidine glycinates as selective inhibitors for h-NTPDases. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2022.106196 (http://dx.doi.org/10.1016/j.bioorg.2022.106196)
Gangar, Mukesh; Goyal, Sandeep; Raykar, Digambar; Khurana, Princy; Martis, Ashwita M.; Goswami, Avijit; Ghoshal, Ishani; Nagare, Yadav; Raikar, Santosh; Mukherjee, Apurba; Cyriac, Rajath; Paquin, Jean-Francois; Kulkarni, Aditya; Patel, Ketul, V. (2022). Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2021.105549 (http://dx.doi.org/10.1016/j.bioorg.2021.105549)
Bouchard, Corinne; Grenier, Alexe; Cardinal, Sebastien; Belanger, Sarah; Voyer, Normand; Pouliot, Roxane. (2022). Antipsoriatic Potential of Quebecol and Its Derivatives. PHARMACEUTICS. DOI: 10.3390/pharmaceutics14061129 (http://dx.doi.org/10.3390/pharmaceutics14061129)
Mangion, Mathias; Robert, Marc-Andre; Slivac, Igor; Gilbert, Renald; Gaillet, Bruno. (2022). Production and Use of Gesicles for Nucleic Acid Delivery. MOLECULAR BIOTECHNOLOGY. DOI: 10.1007/s12033-021-00389-6 (http://dx.doi.org/10.1007/s12033-021-00389-6)
Henault, Mathieu; Marsit, Souhir; Charron, Guillaume; Landry, Christian, R.. (2022). Hybridization drives mitochondrial DNA degeneration and metabolic shift in a species with biparental mitochondrial inheritance. GENOME RESEARCH. DOI: 10.1101/gr.276885.122 (http://dx.doi.org/10.1101/gr.276885.122)
Raiche-Marcoux, Gabrielle; Loiseau, Alexis; Maranda, Cloe; Poliquin, Audree; Boisselier, Elodie. (2022). Parametric Drug Release Optimization of Anti-Inflammatory Drugs by Gold Nanoparticles for Topically Applied Ocular Therapy. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms232416191 (http://dx.doi.org/10.3390/ijms232416191)
Seguin, Jean-Christophe; Fernandez, Xavier; Boudreau, Stephane; Voyer, Normand. (2022). Chemical Composition of the Unexplored Volatile Fraction of Betula glandulosa, a Prevalent Shrub in Nunavik, Quebec. CHEMISTRY & BIODIVERSITY. DOI: 10.1002/cbdv.202100871 (http://dx.doi.org/10.1002/cbdv.202100871)
Mozzachiodi, Simone; Bai, Feng-Yan; Baldrian, Petr; Bell, Graham; Boundy-Mills, Kyria; Buzzini, Pietro; Cadez, Neza; Cubillos, Francisco A.; Dashko, Sofia; Dimitrov, Roumen; Fisher, Kaitlin J.; Gibson, Brian; Gouliamova, Dilnora; Greig, Duncan; Heistinger, Lina; Hittinger, Chris Todd; Jecmenica, Marina; Koufopanou, Vassiliki; Landry, Christian R.; Masinova, Tereza; Naumova, Elena S.; Opulente, Dana; Pena, Jacqueline J.; Petrovic, Uros; Tsai, Isheng Jason; Turchetti, Benedetta; Villarreal, Pablo; Yurkov, Andrey; Liti, Gianni; Boynton, Primrose. (2022). Yeasts from temperate forests. YEAST. DOI: 10.1002/yea.3699 (http://dx.doi.org/10.1002/yea.3699)
St-Gelais, Jacob; Leclerc, Christina; Giguere, Denis. (2022). Synthesis of fluorinated thiodigalactoside analogues. CARBOHYDRATE RESEARCH. DOI: 10.1016/j.carres.2021.108481 (http://dx.doi.org/10.1016/j.carres.2021.108481)
Loehr, Jeremy; Tchara, Pata-Eting Kougnassoukou; Gonthier, Kevin; Noufi, Chahinez; Linteau, Naomie; Audet-Walsh, Etienne; Lambert, Jean-Philippe. (2022). A Nutrient-Based Cellular Model to Characterize Acetylation-Dependent Protein-Protein Interactions. FRONTIERS IN MOLECULAR BIOSCIENCES. DOI: 10.3389/fmolb.2022.831758 (http://dx.doi.org/10.3389/fmolb.2022.831758)
Becker, Yann L. C.; Gagne, Jean-Philippe; Julien, Anne-Sophie; Levesque, Tania; Allaeys, Isabelle; Gougeard, Nadine; Rubio, Vicente; Boisvert, Francois-Michel; Jean, Dominique; Wagner, Eric; Poirier, Guy G.; Fortin, Paul R.; Boilard, Eric. (2022). Identification of Mitofusin 1 and Complement Component 1q Subcomponent Binding Protein as Mitochondrial Targets in Systemic Lupus Erythematosus. ARTHRITIS & RHEUMATOLOGY. DOI: 10.1002/art.42082 (http://dx.doi.org/10.1002/art.42082)
Maggiore, Anna; Casale, Assunta Maria; Toscanelli, Walter; Cappucci, Ugo; Rotili, Dante; Grieco, Maddalena; Gagne, Jean-Philippe; Poirier, Guy G.; D'Erme, Maria; Piacentini, Lucia. (2022). Neuroprotective Effects of PARP Inhibitors in Drosophila Models of Alzheimer's Disease. CELLS. DOI: 10.3390/cells11081284 (http://dx.doi.org/10.3390/cells11081284)
Cornuault, Jeffrey K.; Byatt, Gabriel; Paquet, Marie-Eve; De Koninck, Paul; Moineau, Sylvain. (2022). Zebrafish: a big fish in the study of the gut microbiota. CURRENT OPINION IN BIOTECHNOLOGY. DOI: 10.1016/j.copbio.2021.09.007 (http://dx.doi.org/10.1016/j.copbio.2021.09.007)
Bedard, Camille; Cisneros, Angel F.; Jordan, David; Landry, Christian R.. (2022). Correlation between protein abundance and sequence conservation: what do recent experiments say?. CURRENT OPINION IN GENETICS & DEVELOPMENT. DOI: 10.1016/j.gde.2022.101984 (http://dx.doi.org/10.1016/j.gde.2022.101984)
Mhone, Amos Lucky; Makumi, Angela; Odaba, Josiah; Guantai, Linda; Gunathilake, K. M. Damitha; Loignon, Stephanie; Ngugi, Caroline Wangari; Akhwale, Juliah Khayeli; Moineau, Sylvain; Svitek, Nicholas. (2022). Salmonella Enteritidis Bacteriophages Isolated from Kenyan Poultry Farms Demonstrate Time-Dependent Stability in Environments Mimicking the Chicken Gastrointestinal Tract. VIRUSES-BASEL. DOI: 10.3390/v14081788 (http://dx.doi.org/10.3390/v14081788)
Manojlovic-Stojanoski, Milica; Lavrnja, Irena; Stevanovic, Ivana; Trifunovic, Svetlana; Ristic, Natasa; Nestorovic, Natasa; Sevigny, Jean; Nedeljkovic, Nadezda; Laketa, Danijela. (2022). Antenatal Dexamethasone Treatment Induces Sex-dependent Upregulation of NTPDase1/CD39 and Ecto-5MODIFIER LETTER PRIME-nucleotidase/CD73 in the Rat Fetal Brain. CELLULAR AND MOLECULAR NEUROBIOLOGY. DOI: 10.1007/s10571-021-01081-8 (http://dx.doi.org/10.1007/s10571-021-01081-8)
Braga, Luciano Gama; Garand, Chantal; Elowe, Sabine. (2022). Considerations for studying phosphorylation of the mitotic checkpoint pseudokinase BUBR1. PSEUDOKINASES. DOI: 10.1016/bs.mie.2022.03.045 (http://dx.doi.org/10.1016/bs.mie.2022.03.045)
Zandian, Mohamad; Jang, Suk Min; Lachance, Catherine; Acharya, Arpan; Byrareddy, Siddappa N.; Cote, Jacques; Kutateladze, Tatiana G.. (2022). Characterization of multiple interactions between the envelope E protein of SARS-CoV-2 and human BRD4. STAR PROTOCOLS. DOI: 10.1016/j.xpro.2022.101853 (http://dx.doi.org/10.1016/j.xpro.2022.101853)
Sudarshan, Deepthi; Avvakumov, Nikita; Lalonde, Marie-Eve; Alerasool, Nader; Joly-Beauparlant, Charles; Jacquet, Karine; Mameri, Amel; Lambert, Jean-Philippe; Rousseau, Justine; Lachance, Catherine; Paquet, Eric; Herrmann, Lara; Setty, Samarth Thonta; Loehr, Jeremy; Bernardini, Marcus Q.; Rouzbahman, Marjan; Gingras, Anne-Claude; Coulombe, Benoit; Droit, Arnaud; Taipale, Mikko; Doyon, Yannick; Cote, Jacques. (2022). Recurrent chromosomal translocations in sarcomas create a megacomplex that mislocalizes NuA4/TIP60 to Polycomb target loci. GENES & DEVELOPMENT. DOI: 10.1101/gad.348982.121 (http://dx.doi.org/10.1101/gad.348982.121)
Barry, Raymond Mario; Sacco, Olivia; Mameri, Amel; Stojaspal, Martin; Kartsonis, William; Shah, Pooja; De Ioannes, Pablo; Hofr, Ctirad; Cote, Jacques; Sfeir, Agnel. (2022). Rap1 regulates TIP60 function during fate transition between two-cell-like and pluripotent states. GENES & DEVELOPMENT. DOI: 10.1101/gad.349039.121 (http://dx.doi.org/10.1101/gad.349039.121)
Landry, Christian R.; Liti, Gianni. (2022). Editorial overview: evolutionary genetics: how a tiny model system enables big discoveries. CURRENT OPINION IN GENETICS & DEVELOPMENT. DOI: 10.1016/j.gde.2022.102000 (http://dx.doi.org/10.1016/j.gde.2022.102000)
Devoucoux, Maeva; Roques, Celine; Lachance, Catherine; Lashgari, Anahita; Joly-Beauparlant, Charles; Jacquet, Karine; Alerasool, Nader; Prudente, Alexandre; Taipale, Mikko; Droit, Arnaud; Lambert, Jean-Philippe; Hussein, Samer M. I.; Cote, Jacques. (2022). MRG Proteins Are Shared by Multiple Protein Complexes With Distinct Functions. MOLECULAR & CELLULAR PROTEOMICS. DOI: 10.1016/j.mcpro.2022.100253 (http://dx.doi.org/10.1016/j.mcpro.2022.100253)
Chauhan, Jagat S.; Hoelzel, Michael; Lambert, Jean-Philippe; Buffa, Francesca M.; Goding, Colin R.. (2022). The MITF regulatory network in melanoma. PIGMENT CELL & MELANOMA RESEARCH. DOI: 10.1111/pcmr.13053 (http://dx.doi.org/10.1111/pcmr.13053)
Luscher, Bernhard; Ahel, Ivan; Altmeyer, Matthias; Ashworth, Alan; Bai, Peter; Chang, Paul; Cohen, Michael; Corda, Daniela; Dantzer, Francoise; Daugherty, Matthew D.; Dawson, Ted M.; Dawson, Valina L.; Deindl, Sebastian; Fehr, Anthony R.; Feijs, Karla L. H.; Filippov, Dmitri V.; Gagne, Jean-Philippe; Grimaldi, Giovanna; Guettler, Sebastian; Hoch, Nicolas C.; Hottiger, Michael O.; Korn, Patricia; Kraus, W. Lee; Ladurner, Andreas; Lehtio, Lari; Leung, Anthony K. L.; Lord, Christopher J.; Mangerich, Aswin; Matic, Ivan; Matthews, Jason; Moldovan, George-Lucian; Moss, Joel; Natoli, Gioacchino; Nielsen, Michael L.; Niepel, Mario; Nolte, Friedrich; Pascal, John; Paschal, Bryce M.; Pawlowski, Krzysztof; Poirier, Guy G.; Smith, Susan; Timinszky, Gyula; Wang, Zhao-Qi; Yelamos, Jose; Yu, Xiaochun; Zaja, Roko; Ziegler, Mathias. (2022). ADP-ribosyltransferases, an update on function and nomenclature. FEBS JOURNAL. DOI: 10.1111/febs.16142 (http://dx.doi.org/10.1111/febs.16142)
2021
O'Sullivan, Julia; Mersaoui, Sofiane Y.; Poirier, Guy; Masson, Jean-Yves. (2021). Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. DOI: 10.3791/62553 (http://dx.doi.org/10.3791/62553)
Vincent, Thierry; Gaillet, Bruno; Garnier, Alain. (2021). Optimisation of Cytochrome P450 BM3 Assisted by Consensus-Guided Evolution. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY. DOI: 10.1007/s12010-021-03573-1 (http://dx.doi.org/10.1007/s12010-021-03573-1)
Genois, Marie-Michelle; Gagne, Jean-Philippe; Yasuhara, Takaaki; Jackson, Jessica; Saxena, Sneha; Langelier, Marie-France; Ahel, Ivan; Bedford, Mark T.; Pascal, John M.; Vindigni, Alessandro; Poirier, Guy G.; Zou, Lee. (2021). CARM1 regulates replication fork speed and stress response by stimulating PARP1. MOLECULAR CELL. DOI: 10.1016/j.molcel.2020.12.010 (http://dx.doi.org/10.1016/j.molcel.2020.12.010)
Nabeel-Shah, Syed; Garg, Jyoti; Tchara, Pata-Eting Kougnassoukou; Pearlman, Ronald E.; Lambert, Jean-Philippe; Tetrahymena, Jeffrey. (2021). Functional proteomics protocol for the identification of interaction partners in Tetrahymena thermophila. STAR PROTOCOLS. DOI: 10.1016/j.xpro.2021.100362 (http://dx.doi.org/10.1016/j.xpro.2021.100362)
Marsit, S.; Henault, M.; Charron, G.; Fijarczyk, A.; Landry, C. R.. (2021). The neutral rate of whole-genome duplication varies among yeast species and their hybrids. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-021-23231-8 (http://dx.doi.org/10.1038/s41467-021-23231-8)
Cheng, Xue; Cote, Valerie; Cote, Jacques. (2021). NuA4 and SAGA acetyltransferase complexes cooperate for repair of DNA breaks by homologous recombination. PLOS GENETICS. DOI: 10.1371/journal.pgen.1009459 (http://dx.doi.org/10.1371/journal.pgen.1009459)
Go, Christopher D.; Knight, James D. R.; Rajasekharan, Archita; Rathod, Bhavisha; Hesketh, Geoffrey G.; Abe, Kento T.; Youn, Ji-Young; Samavarchi-Tehrani, Payman; Zhang, Hui; Zhu, Lucie Y.; Popiel, Evelyn; Lambert, Jean-Philippe; Coyaud, Etienne; Cheung, Sally W. T.; Rajendran, Dushyandi; Wong, Cassandra J.; Antonicka, Hana; Pelletier, Laurence; Palazzo, Alexander F.; Shoubridge, Eric A.; Raught, Brian; Gingras, Anne-Claude. (2021). A proximity-dependent biotinylation map of a human cell. NATURE. DOI: 10.1038/s41586-021-03592-2 (http://dx.doi.org/10.1038/s41586-021-03592-2)
Ahmad, Salar; Cote, Valerie; Cote, Jacques. (2021). DNA Damage-Induced Phosphorylation of Histone H2A at Serine 15 Is Linked to DNA End Resection. MOLECULAR AND CELLULAR BIOLOGY. DOI: 10.1128/MCB.00056-21 (http://dx.doi.org/10.1128/MCB.00056-21)
Dandage, Rohan; Landry, Christian R.. (2021). Identifying features of genome evolution to exploit cancer vulnerabilities. CELL SYSTEMS. DOI: 10.1016/j.cels.2021.08.007 (http://dx.doi.org/10.1016/j.cels.2021.08.007)
Philippe, Cecile; Moineau, Sylvain. (2021). The endless battle between phages and CRISPR-Cas systems in Streptococcus thermophilus. BIOCHEMISTRY AND CELL BIOLOGY. DOI: 10.1139/bcb-2020-0593 (http://dx.doi.org/10.1139/bcb-2020-0593)
Zarrouk, Karima; Zhu, Xiaojun; Pham, Van Dung; Goyette, Nathalie; Piret, Jocelyne; Shi, Rong; Boivin, Guy. (2021). Impact of Amino Acid Substitutions in Region II and Helix K of Herpes Simplex Virus 1 and Human Cytomegalovirus DNA Polymerases on Resistance to Foscarnet. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. DOI: 10.1128/AAC.00390-21 (http://dx.doi.org/10.1128/AAC.00390-21)
Ahmad, Salar; Cote, Valerie; Chengid, Xue; Bourriquen, Gaelle; Sapountzi, Vasileia; Altafid, Mohammed; Cote, Jacques. (2021). Antagonistic relationship of NuA4 with the non-homologous end-joining machinery at DNA damage sites. PLOS GENETICS. DOI: 10.1371/journal.pgen.1009816 (http://dx.doi.org/10.1371/journal.pgen.1009816)
Velot, Lauriane; Lessard, Frederic; Berube-Simard, Felix-Antoine; Tav, Christophe; Neveu, Bertrand; Teyssier, Valentine; Boudaoud, Imene; Dionne, Ugo; Lavoie, Noemie; Bilodeau, Steve; Pouliot, Frederic; Bisson, Nicolas. (2021). Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner. MOLECULAR & CELLULAR PROTEOMICS. DOI: 10.1016/j.mcpro.2021.100064 (http://dx.doi.org/10.1016/j.mcpro.2021.100064)
Soltani, Samira; Couture, Frederic; Boutin, Yvan; Ben Said, Laila; Cashman-Kadri, Samuel; Subirade, Muriel; Biron, Eric; Fliss, Ismail. (2021). In vitro investigation of gastrointestinal stability and toxicity of 3-hyrdoxy-propionaldehyde (reuterin) produced by Lactobacillus reuteri. TOXICOLOGY REPORTS. DOI: 10.1016/j.toxrep.2021.03.025 (http://dx.doi.org/10.1016/j.toxrep.2021.03.025)
Pastuszka, Adeline; Beauruelle, Clemence; Camiade, Emilie; Rousseau, Genevieve M.; Moineau, Sylvain; Mereghetti, Laurent; Horvath, Philippe; Lanotte, Philippe. (2021). Functional Study of the Type II-A CRISPR-Cas System of Streptococcus agalactiae Hypervirulent Strains. CRISPR JOURNAL. DOI: 10.1089/crispr.2020.0145 (http://dx.doi.org/10.1089/crispr.2020.0145)
Mosterd, Cas; Rousseau, Genevieve M.; Moineau, Sylvain. (2021). A short overview of the CRISPR-Cas adaptation stage. CANADIAN JOURNAL OF MICROBIOLOGY. DOI: 10.1139/cjm-2020-0212 (http://dx.doi.org/10.1139/cjm-2020-0212)
Cornuault, Jeffrey K.; Moineau, Sylvain. (2021). Induction and Elimination of Prophages Using CRISPR Interference. CRISPR JOURNAL. DOI: 10.1089/crispr.2021.0026 (http://dx.doi.org/10.1089/crispr.2021.0026)
Horianopoulos, Linda C.; Gluck-Thaler, Emile; Gelber, Isabelle Benoit; Cowen, Leah E.; Geddes-McAlister, Jennifer; Landry, Christian R.; Schwartz, Ilan S.; Scott, James A.; Sellam, Adnane; Sheppard, Donald C.; Spribille, Toby; Subramaniam, Rajagopal; Walker, Allison K.; Harris, Steven D.; Shapiro, Rebecca S.; Gerstein, Aleeza C.. (2021). The Canadian Fungal Research Network: current challenges and future opportunities. CANADIAN JOURNAL OF MICROBIOLOGY. DOI: 10.1139/cjm-2020-0263 (http://dx.doi.org/10.1139/cjm-2020-0263)
Villot, Romain; Poirier, Audrey; Bakan, Inan; Boulay, Karine; Fernandez, Erlinda; Devillers, Romain; Gama-Braga, Luciano; Tribouillard, Laura; Gagne, Andreanne; Duchesne, Ema; Caron, Danielle; Berube, Jean-Sebastien; Berube, Jean-Christophe; Coulombe, Yan; Orain, Michele; Gelinas, Yves; Gobeil, Stephane; Bosse, Yohan; Masson, Jean-Yves; Elowe, Sabine; Bilodeau, Steve; Manem, Venkata; Joubert, Philippe; Mallette, Frederick A.; Laplante, Mathieu. (2021). ZNF768 links oncogenic RAS to cellular senescence. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-021-24932-w (http://dx.doi.org/10.1038/s41467-021-24932-w)
Plante, Samuel; Landry, Christian R.. (2021). Closely related budding yeast species respond to different ecological signals for spore activation. YEAST. DOI: 10.1002/yea.3538 (http://dx.doi.org/10.1002/yea.3538)
Berger, Caroline M.; Landry, Christian R.. (2021). Yeast proteins do not practice social distancing as species hybridize. CURRENT GENETICS. DOI: 10.1007/s00294-021-01188-x (http://dx.doi.org/10.1007/s00294-021-01188-x)
Rodriguez-Martinez, Aitor; Trapero, Carla; Vidal, August; Piulats, Josep Maria; Gomez de Aranda, Inmaculada; Sevigny, Jean; Fernandez-Montoli, Maria Eulalia; Ponce, Jordi; Matias-Guiu, Xavier; Martin-Satue, Mireia. (2021). Characterization of the Endometrial MSC Marker Ectonucleoside Triphosphate Diphosphohydrolase-2 (NTPDase2/CD39L1) in Low- and High-Grade Endometrial Carcinomas: Loss of Stromal Expression in the Invasive Phenotypes. JOURNAL OF PERSONALIZED MEDICINE. DOI: 10.3390/jpm11050331 (http://dx.doi.org/10.3390/jpm11050331)
Aziz, Hamid; Mahmood, Abid; Zaib, Sumera; Saeed, Aamer; El-Seedi, Hesham R.; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2021). Synthesis, characterization, alkaline phosphatase inhibition assay and molecular modeling studies of 1-benzylidene-2-(4-tert- butylthiazol-2-yl) hydrazines. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. DOI: 10.1080/07391102.2020.1802336 (http://dx.doi.org/10.1080/07391102.2020.1802336)
Schmidt, Thais F.; Riske, Karin A.; Caseli, Luciano; Salesse, Christian. (2021). Dengue fusion peptide in Langmuir monolayers: A binding parameter study. BIOPHYSICAL CHEMISTRY. DOI: 10.1016/j.bpc.2021.106553 (http://dx.doi.org/10.1016/j.bpc.2021.106553)
Klein, Brianna J.; Cox, Khan L.; Jang, Suk Min; Singh, Rohit K.; Cote, Jacques; Poirier, Michael G.; Kutateladze, Tatiana G.. (2021). Structural and biophysical characterization of the nucleosome-binding PZP domain. STAR PROTOCOLS. DOI: 10.1016/j.xpro.2021.100479 (http://dx.doi.org/10.1016/j.xpro.2021.100479)
Pham, N. T. Hang; Letourneau, Myriam; Fortier, Marlene; Begin, Gabriel; Al-Abdul-Wahid, M. Sameer; Pucci, Fabrizio; Folch, Benjamin; Rooman, Marianne; Chatenet, David; St-Pierre, Yves; Lague, Patrick; Calmettes, Charles; Doucet, Nicolas. (2021). Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7. JOURNAL OF BIOLOGICAL CHEMISTRY. DOI: 10.1016/j.jbc.2021.101308 (http://dx.doi.org/10.1016/j.jbc.2021.101308)
Dore, Laurie; Pageau, Gabrielle; Bourque-Leblanc, Francoise; Dupuis, Marie-Eve; Lessard-Hurtubise, Roxanne; Lacasse, Genevieve; Plante, Pier-Luc; Labrie, Simon; Jolicoeur, Alice P.; Rousseau, Genevieve M.; Tremblay, Denise M.; Moineau, Sylvain. (2021). Complete Genome Sequences of 10 Lactococcal Skunavirus Phages Isolated from Cheddar Cheese Whey Samples in Canada. MICROBIOLOGY RESOURCE ANNOUNCEMENTS. DOI: 10.1128/MRA.00098-21 (http://dx.doi.org/10.1128/MRA.00098-21)
Soltani, Samira; Hammami, Riadh; Cotter, Paul D.; Rebuffat, Sylvie; Ben Said, Laila; Gaudreau, Helene; Bedard, Francois; Biron, Eric; Drider, Djamel; Fliss, Ismail. (2021). Bacteriocins as a new generation of antimicrobials: toxicity aspects and regulations. FEMS MICROBIOLOGY REVIEWS. DOI: 10.1093/femsre/fuaa039 (http://dx.doi.org/10.1093/femsre/fuaa039)
Hosseini, Nava; Paquet, Valerie E.; Chehreghani, Mahdi; Moineau, Sylvain; Charette, Steve J.. (2021). Phage Cocktail Development against Aeromonas salmonicida subsp. salmonicida Strains Is Compromised by a Prophage. VIRUSES-BASEL. DOI: 10.3390/v13112241 (http://dx.doi.org/10.3390/v13112241)
Jungblut, Anne D.; Raymond, Frederic; Dion, Moira B.; Moineau, Sylvain; Mohit, Vani; Nguyen, Guillaume Quang; Deraspe, Maxime; Francovic-Fontaine, Elina; Lovejoy, Connie; Culley, Alexander I.; Corbeil, Jacques; Vincent, Warwick F.. (2021). Genomic diversity and CRISPR-Cas systems in the cyanobacterium Nostoc in the High Arctic. ENVIRONMENTAL MICROBIOLOGY. DOI: 10.1111/1462-2920.15481 (http://dx.doi.org/10.1111/1462-2920.15481)
Babou Kammoe, Romuald Brice; Kauffenstein, Gilles; Pelletier, Julie; Robaye, Bernard; Sevigny, Jean. (2021). NTPDase1 Modulates Smooth Muscle Contraction in Mice Bladder by Regulating Nucleotide Receptor Activation Distinctly in Male and Female. BIOMOLECULES. DOI: 10.3390/biom11020147 (http://dx.doi.org/10.3390/biom11020147)
Gagne, Laurence M.; Morin, Nadine; Lavoie, Noemie; Bisson, Nicolas; Lambert, Jean-Philippe; Mallette, Frederick A.; Huot, Marc-Etienne. (2021). Tyrosine phosphorylation of DEPTOR functions as a molecular switch to activate mTOR signaling. JOURNAL OF BIOLOGICAL CHEMISTRY. DOI: 10.1016/j.jbc.2021.101291 (http://dx.doi.org/10.1016/j.jbc.2021.101291)
Nabeel-Shah, Syed; Garg, Jyoti; Saettone, Alejandro; Ashraf, Kanwal; Lee, Hyunmin; Wahab, Suzanne; Ahmed, Nujhat; Fine, Jacob; Derynck, Joanna; Pu, Shuye; Ponce, Marcelo; Marcon, Edyta; Zhang, Zhaolei; Greenblatt, Jack F.; Pearlman, Ronald E.; Lambert, Jean-Philippe; Fillingham, Jeffrey. (2021). Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkab413 (http://dx.doi.org/10.1093/nar/gkab413)
Dion, Moira B.; Plante, Pier-Luc; Zufferey, Edwige; Shah, Shiraz A.; Corbeil, Jacques; Moineau, Sylvain. (2021). Streamlining CRISPR spacer-based bacterial host predictions to decipher the viral dark matter. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkab133 (http://dx.doi.org/10.1093/nar/gkab133)
Achigar, Rodrigo; Scarrone, Martina; Rousseau, Genevieve M.; Philippe, Cecile; Machado, Felipe; Duvos, Valentina; Campot, Maria Pia; Dion, Moira B.; Shao, Yuyu; Pianzzola, Maria Julia; Moineau, Sylvain. (2021). Ectopic Spacer Acquisition in Streptococcus thermophilus CRISPR3 Array. MICROORGANISMS. DOI: 10.3390/microorganisms9030512 (http://dx.doi.org/10.3390/microorganisms9030512)
Suzuki, Godai; Saito, Yutaka; Seki, Motoaki; Evans-Yamamoto, Daniel; Negishi, Mikiko; Kakoi, Kentaro; Kawai, Hiroki; Landry, Christian R.; Yachie, Nozomu; Mitsuyama, Toutai. (2021). Machine learning approach for discrimination of genotypes based on bright-field cellular images. NPJ SYSTEMS BIOLOGY AND APPLICATIONS. DOI: 10.1038/s41540-021-00190-w (http://dx.doi.org/10.1038/s41540-021-00190-w)
Fage, Clement; Lemire, Nicolas; Moineau, Sylvain. (2021). Delivery of CRISPR-Cas systems using phage-based vectors. CURRENT OPINION IN BIOTECHNOLOGY. DOI: 10.1016/j.copbio.2020.11.012 (http://dx.doi.org/10.1016/j.copbio.2020.11.012)
Fijarczyk, Anna; Henault, Mathieu; Marsit, Souhir; Charron, Guillaume; Landry, Christian R.. (2021). Heterogeneous Mutation Rates and Spectra in Yeast Hybrids. GENOME BIOLOGY AND EVOLUTION. DOI: 10.1093/gbe/evab282 (http://dx.doi.org/10.1093/gbe/evab282)
Mosterd, Cas; Moineau, Sylvain. (2021). Primed CRISPR-Cas Adaptation and Impaired Phage Adsorption in Streptococcus mutans. MSPHERE. DOI: 10.1128/mSphere.00185-21 (http://dx.doi.org/10.1128/mSphere.00185-21)
Metivier, Mathieu; Gallaud, Emmanuel; Thomas, Alexandre; Pascal, Aude; Gagne, Jean-Philippe; Poirier, Guy G.; Chretien, Denis; Gibeaux, Romain; Richard-Parpaillon, Laurent; Benaud, Christelle; Giet, Regis. (2021). Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly. CURRENT BIOLOGY. DOI: 10.1016/j.cub.2020.11.009 (http://dx.doi.org/10.1016/j.cub.2020.11.009)
Alhammad, Yousef M. O.; Kashipathy, Maithri M.; Roy, Anuradha; Gagne, Jean-Philippe; McDonald, Peter; Gao, Philip; Nonfoux, Louis; Battaile, Kevin P.; Johnson, David K.; Holmstrom, Erik D.; Poirier, Guy G.; Lovell, Scott; Fehr, Anthony R.. (2021). The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase. JOURNAL OF VIROLOGY. DOI: 10.1128/JVI.01969-20 (http://dx.doi.org/10.1128/JVI.01969-20)
Laliberte-Gagne, Marie-Eve; Bolduc, Marilene; Garneau, Caroline; Olivera-Ugarte, Santa-Mariela; Savard, Pierre; Leclerc, Denis. (2021). Modulation of Antigen Display on PapMV Nanoparticles Influences Its Immunogenicity. VACCINES. DOI: 10.3390/vaccines9010033 (http://dx.doi.org/10.3390/vaccines9010033)
Schachter, J.; Alvarez, C. L.; Bazzi, Z.; Faillace, M. P.; Corradi, G.; Hattab, C.; Rinaldi, D. E.; Gonzalez-Lebrero, R.; Pucci Molineris, M.; Sevigny, J.; Ostuni, M. A.; Schwarzbaum, P. J.. (2021). Extracellular ATP hydrolysis in Caco-2 human intestinal cell line. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. DOI: 10.1016/j.bbamem.2021.183679 (http://dx.doi.org/10.1016/j.bbamem.2021.183679)
Dionne, Ugo; Bourgault, Emilie; Dube, Alexandre K.; Bradley, David; Chartier, Francois J. M.; Dandage, Rohan; Dibyachintan, Soham; Despres, Philippe C.; Gish, Gerald D.; Pham, N. T. Hang; Letourneau, Myriam; Lambert, Jean-Philippe; Doucet, Nicolas; Bisson, Nicolas; Landry, Christian R.. (2021). Protein context shapes the specificity of SH3 domain-mediated interactions in vivo. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-021-21873-2 (http://dx.doi.org/10.1038/s41467-021-21873-2)
Hadicke, Andre; Coutinho, Ana; Roy, Sarah; Otis, Francois; Lhor, Mustapha; Cantin, Line; Prieto, Manuel; Voyer, Normand; Salesse, Christian. (2021). Membrane binding properties of the C-terminal segment of retinol dehydrogenase 8. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. DOI: 10.1016/j.bbamem.2021.183605 (http://dx.doi.org/10.1016/j.bbamem.2021.183605)
Bernier, Sarah C.; Millette, Marc-Antoine; Roy, Sarah; Cantin, Line; Coutinho, Ana; Salesse, Christian. (2021). Structural information and membrane binding of truncated RGS9-1 Anchor Protein and its C-terminal hydrophobic segment. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. DOI: 10.1016/j.bbamem.2021.183566 (http://dx.doi.org/10.1016/j.bbamem.2021.183566)
Pare, Guillaume; Vitry, Julien; Merchant, Michael L.; Vaillancourt, Myriam; Murru, Andrea; Shen, Yunyun; Elowe, Sabine; Lahoud, Mireille H.; Naccache, Paul H.; McLeish, Kenneth R.; Fernandes, Maria J.. (2021). The Inhibitory Receptor CLEC12A Regulates PI3K-Akt Signaling to Inhibit Neutrophil Activation and Cytokine Release. FRONTIERS IN IMMUNOLOGY. DOI: 10.3389/fimmu.2021.650808 (http://dx.doi.org/10.3389/fimmu.2021.650808)
Hoikkala, Ville; Ravantti, Janne; Diez-Villasenor, Cesar; Tiirola, Marja; Conrad, Rachel A.; McBride, Mark J.; Moineau, Sylvain; Sundberg, Lotta-Riina. (2021). Cooperation between Different CRISPR-Cas Types Enables Adaptation in an RNA-Targeting System. MBIO. DOI: 10.1128/mBio.03338-20 (http://dx.doi.org/10.1128/mBio.03338-20)
Paquet-Cote, Pierre-Alexandre; Alejaldre, Lorea; Verreault, Camille Lapointe; Gobeil, Sophie M. C.; Lamoureux, Rosalie; Bedard, Laurie; Normandeau, Charles-Olivier; Lemay-St-Denis, Claudele; Pelletier, Joelle N.; Voyer, Normand. (2021). Development of sulfahydantoin derivatives as β-lactamase inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. DOI: 10.1016/j.bmcl.2021.127781 (http://dx.doi.org/10.1016/j.bmcl.2021.127781)
Bouchard, Megan; Tremblay, Thomas; Pare-Lacroix, Marie-Pier; Gagne-Boulet, Mathieu; Fortin, Sebastien; Giguere, Denis. (2021). Synthetic development of sugar amino acid oligomers towards novel podophyllotoxin analogues. BIOORGANIC & MEDICINAL CHEMISTRY. DOI: 10.1016/j.bmc.2021.116501 (http://dx.doi.org/10.1016/j.bmc.2021.116501)
Bautista, Carla; Marsit, Souhir; Landry, Christian R.. (2021). Interspecific hybrids show a reduced adaptive potential under DNA damaging conditions. EVOLUTIONARY APPLICATIONS. DOI: 10.1111/eva.13155 (http://dx.doi.org/10.1111/eva.13155)
Bertrand, Xavier; Chabaud, Laurent; Paquin, Jean-Francois. (2021). Hydrofluorination of Alkenes: A Review. CHEMISTRY-AN ASIAN JOURNAL. DOI: 10.1002/asia.202001403 (http://dx.doi.org/10.1002/asia.202001403)
Picard, Marie-Eve; Cusson, Michel; Sen, Stephanie E.; Shi, Rong. (2021). Rational design of Lepidoptera-specific insecticidal inhibitors targeting farnesyl diphosphate synthase, a key enzyme of the juvenile hormone biosynthetic pathway. JOURNAL OF PESTICIDE SCIENCE. DOI: 10.1584/jpestics.D20-078 (http://dx.doi.org/10.1584/jpestics.D20-078)
Dias, Amanda de Fraga; Scholl, Juliete Nathali; Moritz, Cesar Eduardo Jacintho; Kagami, Luciano Porto; das Neves, Gustavo Machado; Eifler-Lima, Vera Lucia; Cruz-Lopez, Olga; Conejo-Garcia, Ana; Sevigny, Jean; Battastini, Ana Maria Oliveira; Campos, Joaquin Maria; Figueiro, Fabricio. (2021). New insights into cytotoxic mechanisms of bozepinib against glioblastoma. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. DOI: 10.1016/j.ejps.2021.105823 (http://dx.doi.org/10.1016/j.ejps.2021.105823)
Lopes, Daniela Vasconcelos; de Fraga Dias, Amanda; Silva, Luiz Fernando Lopes; Scholl, Juliete Nathali; Sevigny, Jean; Battastini, Ana Maria Oliveira; Figueiro, Fabricio. (2021). Influence of NSAIDs and methotrexate on CD73 expression and glioma cell growth. PURINERGIC SIGNALLING. DOI: 10.1007/s11302-021-09775-w (http://dx.doi.org/10.1007/s11302-021-09775-w)
Rubenich, Dominique S.; de Souza, Priscila O.; Omizzollo, Natalia; Lenz, Gabriela S.; Sevigny, Jean; Braganhol, Elizandra. (2021). Neutrophils: fast and furious-the nucleotide pathway. PURINERGIC SIGNALLING. DOI: 10.1007/s11302-021-09786-7 (http://dx.doi.org/10.1007/s11302-021-09786-7)
Awad, Gamal; Garnier, Alain. (2021). Promising optimization of bacterial cytochrome P450BM3 enzyme production by engineered Escherichia coli BL21. BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY. DOI: 10.1016/j.bcab.2021.101917 (http://dx.doi.org/10.1016/j.bcab.2021.101917)
Tremblay, Thomas; St-Gelais, Jacob; Houde, Maxime; Giguere, Denis. (2021). Polyfluoroglycoside Synthesis via Simple Alkylation of an Anomeric Hydroxyl Group: Access to Fluoroetoposide Analogues. JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1021/acs.joc.0c02841 (http://dx.doi.org/10.1021/acs.joc.0c02841)
Awad, Gamal; Garnier, Alain. (2021). Maximization of saturated fatty acids through the production of P450BM3 monooxygenase in the engineered Escherichia coli. FOOD AND BIOPRODUCTS PROCESSING. DOI: 10.1016/j.fbp.2021.01.001 (http://dx.doi.org/10.1016/j.fbp.2021.01.001)
Berger, Chloe Suzanne; Laroche, Jerome; Maaroufi, Halim; Martin, Helene; Moon, Kyung-Mee; Landry, Christian R.; Foster, Leonard J.; Aubin-Horth, Nadia. (2021). The parasite Schistocephalus solidus secretes proteins with putative host manipulation functions. PARASITES & VECTORS. DOI: 10.1186/s13071-021-04933-w (http://dx.doi.org/10.1186/s13071-021-04933-w)
Robert-Scott, Gabrielle; St-Gelais, Jacob; Giguere, Denis. (2021). Annulative Dimerization of Carbohydrates: Synthesis of Complex C2-Symmetrical 1,4-Dioxane-Sugar Hybrids. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1002/ejoc.202100411 (http://dx.doi.org/10.1002/ejoc.202100411)
Gilbert, Audrey; Langowski, Pauline; Delgado, Marine; Chabaud, Laurent; Pucheault, Mathieu; Paquin, Jean-Francois. (2021). Amine-borane complex-initiated SF5Cl radical addition on alkenes and alkynes (vol 16, pg 3069, 2020). BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.3762/bjoc.17.120 (http://dx.doi.org/10.3762/bjoc.17.120)
Hacene, Youcef Chakib; Loiseau, Alexis; Maio, Vanessa Dos Passos; Grenier, Philippe; Boisselier, Elodie; Bertrand, Nicolas. (2021). Isolating Nanoparticles from Complex Biological Media by Immunoprecipitation. NANO LETTERS. DOI: 10.1021/acs.nanolett.0c05056 (http://dx.doi.org/10.1021/acs.nanolett.0c05056)
Yan, Xiaolin; Kumar, Kiran; Lamarche, Renaud Miclette; Youssef, Hala; Shaw, Gary S.; Marcotte, Isabelle; DeWolf, Christine E.; Warschawski, Dror E.; Boisselier, Elodie. (2021). Interactions between the Cell Membrane Repair Protein S100A10 and Phospholipid Monolayers and Bilayers. LANGMUIR. DOI: 10.1021/acs.langmuir.1c00342 (http://dx.doi.org/10.1021/acs.langmuir.1c00342)
Corbeil, Christopher R.; Manenda, Mahder Seifu; Sulea, Traian; Baardsnes, Jason; Picard, Marie-Eve; Hogues, Herve; Gaudreault, Francis; Deprez, Christophe; Shi, Rong; Purisima, Enrico O.. (2021). Redesigning an antibody H3 loop by virtual screening of a small library of human germline-derived sequences. SCIENTIFIC REPORTS. DOI: 10.1038/s41598-021-00669-w (http://dx.doi.org/10.1038/s41598-021-00669-w)
Drouin, Marika; Henault, Mathieu; Hallin, Johan; Landry, Christian R.. (2021). Testing the Genomic Shock Hypothesis Using Transposable Element Expression in Yeast Hybrids. FRONTIERS IN FUNGAL BIOLOGY. DOI: 10.3389/ffunb.2021.729264 (http://dx.doi.org/10.3389/ffunb.2021.729264)
Dandage, Rohan; Berger, Caroline M.; Gagnon-Arsenault, Isabelle; Moon, Kyung-Mee; Stacey, Richard Greg; Foster, Leonard J.; Landry, Christian R.. (2021). Frequent Assembly of Chimeric Complexes in the Protein Interaction Network of an Interspecies Yeast Hybrid. MOLECULAR BIOLOGY AND EVOLUTION. DOI: 10.1093/molbev/msaa298 (http://dx.doi.org/10.1093/molbev/msaa298)
Braga, Luciano Gama; Prifti, Diogjena Katerina; Garand, Chantal; Saini, Pawan Kumar; Elowe, Sabine. (2021). A quantitative and semiautomated method for determining misaligned and lagging chromosomes during mitosis. MOLECULAR BIOLOGY OF THE CELL. DOI: 10.1091/mbc.E20-09-0585 (http://dx.doi.org/10.1091/mbc.E20-09-0585)
Galloy, Maxime; Lachance, Catherine; Cheng, Xue; Distefano-Gagne, Felix; Cote, Jacques; Fradet-Turcotte, Amelie. (2021). Approaches to Study Native Chromatin-Modifying Complex Activities and Functions. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. DOI: 10.3389/fcell.2021.729338 (http://dx.doi.org/10.3389/fcell.2021.729338)
Laine, Danny; Lessard, Olivier; St-Gelais, Jacob; Giguere, Denis. (2021). From Carbohydrates to Complex Organofluorines: Synthesis, Conformation, and Lipophilicity of Multivicinal-Fluorine-Containing Hexitol Analogues. CHEMISTRY-A EUROPEAN JOURNAL. DOI: 10.1002/chem.202004646 (http://dx.doi.org/10.1002/chem.202004646)
Bilodeau, Steve; Kurat, Christoph Franz; Lambert, Jean-Philippe. (2021). Editorial: The Evolving Chromatin and Transcriptional Landscapes-Emerging Methods, Tools and Techniques. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. DOI: 10.3389/fcell.2021.782776 (http://dx.doi.org/10.3389/fcell.2021.782776)
Lu, Sizhu; Louphrasitthiphol, Pakavarin; Goradia, Nishit; Lambert, Jean-Philippe; Schmidt, Johannes; Chauhan, Jagat; Rughani, Milap G.; Larue, Lionel; Wilmanns, Matthias; Goding, Colin R.. (2021). TBX2 controls a proproliferative gene expression program in melanoma. GENES & DEVELOPMENT. DOI: 10.1101/gad.348746.121 (http://dx.doi.org/10.1101/gad.348746.121)
Niesor, Eric J.; Boivin, Guy; Rheaume, Eric; Shi, Rong; Lavoie, Veronique; Goyette, Nathalie; Picard, Marie-Eve; Perez, Anne; Laghrissi-Thode, Fouzia; Tardif, Jean-Claude. (2021). Inhibition of the 3CL Protease and SARS-CoV-2 Replication by Dalcetrapib. ACS OMEGA. DOI: 10.1021/acsomega.1c01797 (http://dx.doi.org/10.1021/acsomega.1c01797)
Melki, Imene; Allaeys, Isabelle; Tessandier, Nicolas; Levesque, Tania; Cloutier, Nathalie; Laroche, Audree; Vernoux, Nathalie; Becker, Yann; Benk-Fortin, Hadrien; Zufferey, Anne; Rollet-Labelle, Emmanuelle; Pouliot, Marc; Poirier, Guy; Patey, Natacha; Belleannee, Clemence; Soulet, Denis; McKenzie, Steven E.; Brisson, Alain; Tremblay, Marie-Eve; Lood, Christian; Fortin, Paul R.; Boilard, Eric. (2021). Platelets release mitochondrial antigens in systemic lupus erythematosus. SCIENCE TRANSLATIONAL MEDICINE. DOI: 10.1126/scitranslmed.aav5928 (http://dx.doi.org/10.1126/scitranslmed.aav5928)
Lamarre, Mathieu; Tremblay, Thomas; Bansept, Marc-Antoine; Robitaille, Karine; Fradet, Vincent; Giguere, Denis; Boudreau, Denis. (2021). A glycan-based plasmonic sensor for prostate cancer diagnosis. ANALYST. DOI: 10.1039/d1an00789k (http://dx.doi.org/10.1039/d1an00789k)
Lopez, Vittoria; Schaekel, Laura; Schuh, H. J. Maximilian; Schmidt, Michael S.; Mirza, Salahuddin; Renn, Christian; Pelletier, Julie; Lee, Sang-Yong; Sevigny, Jean; Alban, Susanne; Bendas, Gerd; Mueller, Christa E.. (2021). Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39. MARINE DRUGS. DOI: 10.3390/md19020051 (http://dx.doi.org/10.3390/md19020051)
Villot, Romain; Poirier, Audrey; Devillers, Romain; Kolnoguz, Aliona; Elowe, Sabine; Manem, Venkata S. K.; Joubert, Philippe; Mallette, Frederick A.; Laplante, Mathieu. (2021). ZNF768: controlling cellular senescence and proliferation with ten fingers. MOLECULAR & CELLULAR ONCOLOGY. DOI: 10.1080/23723556.2021.1985930 (http://dx.doi.org/10.1080/23723556.2021.1985930)
Elowe, Sabine. (2021). Adventures of the undead at kinetochores. MOLECULAR & CELLULAR ONCOLOGY. DOI: 10.1080/23723556.2021.1876511 (http://dx.doi.org/10.1080/23723556.2021.1876511)
Ullah, Saif; El-Gamal, Mohammed, I; El-Gamal, Randa; Pelletier, Julie; Sevigny, Jean; Shehata, Mahmoud K.; Anbar, Hanan S.; Iqbal, Jamshed. (2021). Synthesis, biological evaluation, and docking studies of novel pyrrolo 2,3-b]pyridine derivatives as both ectonucleotide pyrophosphatase/phosphodiesterase inhibitors and antiproliferative agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. DOI: 10.1016/j.ejmech.2021.113339 (http://dx.doi.org/10.1016/j.ejmech.2021.113339)
Iqbal, Jamshed; Basharat, Ayesha; Bano, Sehrish; Abid, Syed Mobasher Ali; Pelletier, Julie; Sevigny, Jean. (2021). Identification and Expression Analysis of CD73 Inhibitors in Cervical Cancer. MEDICINAL CHEMISTRY. DOI: 10.2174/1573406416666200925141703 (http://dx.doi.org/10.2174/1573406416666200925141703)
Marcus, Joshua M.; Hossain, Mohammed I.; Gagne, Jean-Philippe; Poirier, Guy G.; McMahon, Lori L.; Cowell, Rita M.; Andrabi, Shaida A.. (2021). PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons. NEUROCHEMISTRY INTERNATIONAL. DOI: 10.1016/j.neuint.2021.105077 (http://dx.doi.org/10.1016/j.neuint.2021.105077)
Haas, Clarissa B.; Lovaszi, Marianna; Pacher, Pal; de Souza, Priscila Oliveira; Pelletier, Julie; Leite, Rafael Olive; Sevigny, Jean; Nemeth, Zoltan; Braganhol, Elizandra; Hasko, Gyorgy. (2021). Extracellular ectonucleotidases are differentially regulated in murine tissues and human polymorphonuclear leukocytes during sepsis and inflammation. PURINERGIC SIGNALLING. DOI: 10.1007/s11302-021-09819-1 (http://dx.doi.org/10.1007/s11302-021-09819-1)
St-Gelais, Jacob; Giguere, Denis. (2021). Protecting-Group-Free Synthesis of GB1107: An Orally Active Galectin-3 Antagonist. SYNTHESIS-STUTTGART. DOI: 10.1055/a-1517-7177 (http://dx.doi.org/10.1055/a-1517-7177)
Billaud, Maud; Lamy-Besnier, Quentin; Lossouarn, Julien; Moncaut, Elisabeth; Dion, Moira B.; Moineau, Sylvain; Traore, Fatoumata; Le Chatelier, Emmanuelle; Denis, Catherine; Estelle, Jordi; Achard, Caroline; Zemb, Olivier; Petit, Marie-Agnes. (2021). Analysis of viromes and microbiomes from pig fecal samples reveals that phages and prophages rarely carry antibiotic resistance genes. ISME COMMUNICATIONS. DOI: 10.1038/s43705-021-00054-8 (http://dx.doi.org/10.1038/s43705-021-00054-8)
Rasouli, Hannaneh; Iliuta, Ion; Bougie, Francis; Garnier, Alain; Iliuta, Maria C.. (2021). Enzyme-immobilized flat-sheet membrane contactor for green carbon capture. CHEMICAL ENGINEERING JOURNAL. DOI: 10.1016/j.cej.2021.129587 (http://dx.doi.org/10.1016/j.cej.2021.129587)
Zarrouk, Karima; Zhu, Xiaojun; Goyette, Nathalie; Piret, Jocelyne; Shi, Rong; Boivin, Guy. (2021). Differential impact of various substitutions at codon 715 in region II of HSV-1 and HCMV DNA polymerases. ANTIVIRAL RESEARCH. DOI: 10.1016/j.antiviral.2021.105046 (http://dx.doi.org/10.1016/j.antiviral.2021.105046)
Lazarjan, Vahid Khojasteh; Gashti, Anahita Bakhshizadeh; Feshki, Mohamad; Garnier, Alain; Gosselin, Benoit. (2021). Miniature Fiber-Spectrophotometer for Real-Time Biomarkers Detection. IEEE SENSORS JOURNAL. DOI: 10.1109/JSEN.2021.3072578 (http://dx.doi.org/10.1109/JSEN.2021.3072578)
Vezina-Dawod, Simon; Perreault, Martin; Guay, Louis-David; Gerber, Nicolas; Gobeil, Stephane; Biron, Eric. (2021). Synthesis and biological evaluation of novel 1,4-benzodiazepin-3-one derivatives as potential antitumor agents against prostate cancer. BIOORGANIC & MEDICINAL CHEMISTRY. DOI: 10.1016/j.bmc.2021.116314 (http://dx.doi.org/10.1016/j.bmc.2021.116314)
Schaekel, Laura; Mirza, Salahuddin; Pietsch, Markus; Lee, Sang-Yong; Keuler, Tim; Sylvester, Katharina; Pelletier, Julie; Sevigny, Jean; Pillaiyar, Thanigaimalai; Namasivayam, Vigneshwaran; Guetschow, Michael; Mueller, Christa E.. (2021). 2-Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors. ARCHIV DER PHARMAZIE. DOI: 10.1002/ardp.202100300 (http://dx.doi.org/10.1002/ardp.202100300)
Niyonambaza, Shimwe Dominique; Koudrina, Anna; DeRosa, Maria C.; Boukadoum, Mounir; Miled, Amine; Boisselier, Elodie. (2021). Aptamer-Modified Ultrastable Gold Nanoparticles for Dopamine Detection. IEEE SENSORS JOURNAL. DOI: 10.1109/JSEN.2020.3026159 (http://dx.doi.org/10.1109/JSEN.2020.3026159)
Lachance, Gabriel P.; Soulard, Guillaume; Bouffard, Loic; Boisselier, Elodie; Boukadoum, Mounir; Miled, Amine. (2021). Colorimetric Sensing System for Neurotransmitter Detection Based on Multi-technologies Architecture. 2021 28TH IEEE INTERNATIONAL CONFERENCE ON ELECTRONICS, CIRCUITS, AND SYSTEMS (IEEE ICECS 2021). DOI: 10.1109/ICECS53924.2021.9665507 (http://dx.doi.org/10.1109/ICECS53924.2021.9665507)
Possamai, David; Hanafi, Laila-Aicha; Bellemare-Pelletier, Angelique; Hamelin, Katia; Thebault, Pamela; Hebert, Marie-Josee; Gagnon, Etienne; Leclerc, Denis; Lapointe, Rejean. (2021). MHC class I antigen cross-presentation mediated by PapMV nanoparticles in human antigen-presenting cells is dependent on autophagy. PLOS ONE. DOI: 10.1371/journal.pone.0261987 (http://dx.doi.org/10.1371/journal.pone.0261987)
Azizi, Dariush; Larachi, Faical; Garnier, Alain; Lague, Patrick; Levasseur, Benoit. (2021). Sorption of aqueous amino acid species on sulphidic mineral surfaces-DFTstudy and insights on biosourced-reagent mineral flotation. CANADIAN JOURNAL OF CHEMICAL ENGINEERING. DOI: 10.1002/cjce.23841 (http://dx.doi.org/10.1002/cjce.23841)
Guerin, Louis-Philippe; Le-Bel, Gaetan; Desjardins, Pascale; Couture, Camille; Gillard, Elodie; Boisselier, Elodie; Bazin, Richard; Germain, Lucie; Guerin, Sylvain L.. (2021). The Human Tissue-Engineered Cornea (hTEC): Recent Progress. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms22031291 (http://dx.doi.org/10.3390/ijms22031291)
Sandhu, Bynvant; Perez-Matos, Maria C.; Tran, Stephanie; Singhal, Garima; Syed, Ismail; Feldbruegge, Linda; Mitsuhashi, Shuji; Pelletier, Julie; Huang, Jinhe; Yalcin, Yusuf; Csizmadia, Eva; Tiwari-Heckler, Shilpa; Enjyoji, Keiichi; Sevigny, Jean; Maratos-Flier, Eleftheria; Robson, Simon C.; Jiang, Z. Gordon. (2021). Global deletion of NTPDase3 protects against diet-induced obesity by increasing basal energy metabolism. METABOLISM-CLINICAL AND EXPERIMENTAL. DOI: 10.1016/j.metabol.2021.154731 (http://dx.doi.org/10.1016/j.metabol.2021.154731)
Gravel, Alexia; Marciniak, Alice; Couture, Manon; Doyen, Alain. (2021). Effects of Hexane on Protein Profile, Solubility and Foaming Properties of Defatted Proteins Extracted from Tenebrio molitor Larvae. MOLECULES. DOI: 10.3390/molecules26020351 (http://dx.doi.org/10.3390/molecules26020351)
Ascencio, Diana; Diss, Guillaume; Gagnon-Arsenault, Isabelle; Dube, Alexandre K.; DeLuna, Alexander; Landry, Christian R.. (2021). Expression attenuation as a mechanism of robustness against gene duplication. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. DOI: 10.1073/pnas.2014345118 (http://dx.doi.org/10.1073/pnas.2014345118)
Gilbert, Audrey; Birepinte, Melodie; Paquin, Jean-Francois. (2021). Electron donor-acceptor (EDA)-complex enabled SF5Cl addition on alkenes and alkynes. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2021.109734 (http://dx.doi.org/10.1016/j.jfluchem.2021.109734)
Murtaza, Amna; Afzal, Saira; Zaman, Gohar; Saeed, Aamer; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed; Hassan, Abbas. (2021). Divergent synthesis and elaboration of structure activity relationship for quinoline derivatives as highly selective NTPDase inhibitor. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2021.105240 (http://dx.doi.org/10.1016/j.bioorg.2021.105240)
Gonay, Marie; Batisse, Chloe; Paquin, Jean-Francois. (2021). Recent Advances in the Synthesis of Acyl Fluorides. SYNTHESIS-STUTTGART. DOI: 10.1055/s-0040-1705951 (http://dx.doi.org/10.1055/s-0040-1705951)
Gilbert, Audrey; Langowski, Pauline; Paquin, Jean-Francois. (2021). Synthesis of N-(2-SF5-ethyl)amines and impact of the SF5 substituent on their basicity and lipophilicity. TETRAHEDRON. DOI: 10.1016/j.tet.2021.132424 (http://dx.doi.org/10.1016/j.tet.2021.132424)
Afzal, Saira; Al-Rashida, Mariya; Hameed, Abdul; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2021). Synthesis, In-vitro evaluation and molecular docking studies of oxoindolin phenylhydrazine carboxamides as potent and selective inhibitors of ectonucleoside triphosphate diphosphohydrolase (NTPDase). BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2021.104957 (http://dx.doi.org/10.1016/j.bioorg.2021.104957)
Iqbal, Jamshed; Jacob, Claus; Sevigny, Jean. (2021). Editorial: Metalloenzymes: Potential Drug Targets. FRONTIERS IN PHARMACOLOGY. DOI: 10.3389/fphar.2021.746925 (http://dx.doi.org/10.3389/fphar.2021.746925)
Moison, Celine; Chagraoui, Jalila; Caron, Marie-Christine; Gagne, Jean-Philippe; Coulombe, Yan; Poirier, Guy G.; Masson, Jean-Yves; Sauvageau, Guy. (2021). Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. DOI: 10.1073/pnas.2019408118 (http://dx.doi.org/10.1073/pnas.2019408118)
Gauvreau, Dominic; Lachance, Gabriel P.; Landari, Hamza; Boisselier, Elodie; Boukadoum, Mounir; Messaddeq, Younes; Miled, Amine. (2021). Finite Element Simulation of a Microdroplet Generation System for an Implantable Liquid Sampling Probe. 2021 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (IEEE BIOCAS 2021). DOI: 10.1109/BIOCAS49922.2021.9644950 (http://dx.doi.org/10.1109/BIOCAS49922.2021.9644950)
2020
Afzal, Saira; Al-Rashida, Mariya; Hameed, Abdul; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2020). Functionalized Oxoindolin Hydrazine Carbothioamide Derivatives as Highly Potent Inhibitors of Nucleoside Triphosphate Diphosphohydrolases. FRONTIERS IN PHARMACOLOGY. DOI: 10.3389/fphar.2020.585876 (http://dx.doi.org/10.3389/fphar.2020.585876)
Berube, Christopher; Borgia, Alexandre; Gagnon, Dominic; Mukherjee, Angana; Richard, Dave; Voyer, Normand. (2020). Total Synthesis and Antimalarial Activity of Dominicin, a Cyclic Octapeptide from a Marine Sponge. JOURNAL OF NATURAL PRODUCTS. DOI: 10.1021/acs.jnatprod.9b00936 (http://dx.doi.org/10.1021/acs.jnatprod.9b00936)
Baqi, Younis; Rashed, Mahmoud; Schaekel, Laura; Malik, Enas M.; Pelletier, Julie; Sevigny, Jean; Fiene, Amelie; Mueller, Christa E.. (2020). Development of Anthraquinone Derivatives as Ectonucleoside Triphosphate Diphosphohydrolase (NTPDase) Inhibitors With Selectivity for NTPDase2 and NTPDase3. FRONTIERS IN PHARMACOLOGY. DOI: 10.3389/fphar.2020.01282 (http://dx.doi.org/10.3389/fphar.2020.01282)
Lammers, Monica D.; Aneli, Nyasmin M.; de Oliveira, Gabriela G.; de Oliveira Maciel, Sarah F., V; Zanini, Daniela; Manica, Aline; de Resende e Silva, Debora T.; Bagatini, Margarete D.; Sevigny, Jean; De Sa, Clodoaldo A.; Manfredi, Leandro H.; Cardoso, Andreia M.. (2020). The anti-inflammatory effect of resistance training in hypertensive women: the role of purinergic signaling. JOURNAL OF HYPERTENSION. DOI: 10.1097/HJH.0000000000002578 (http://dx.doi.org/10.1097/HJH.0000000000002578)
Azambuja, J. H.; Schuh, R. S.; Michels, L. R.; Gelsleichter, N. E.; Beckenkamp, L. R.; Iser, I. C.; Lenz, G. S.; De Oliveira, F. H.; Venturin, G.; Greggio, S.; DaCosta, J. C.; Wink, M. R.; Sevigny, J.; Stefani, M. A.; Battastini, A. M. O.; Teixeira, H. F.; Braganhol, E.. (2020). Nasal Administration of Cationic Nanoemulsions as CD73-siRNA Delivery System for Glioblastoma Treatment: a New Therapeutical Approach. MOLECULAR NEUROBIOLOGY. DOI: 10.1007/s12035-019-01730-6 (http://dx.doi.org/10.1007/s12035-019-01730-6)
Nabeel-Shah, Syed; Ashraf, Kanwal; Saettone, Alejandro; Garg, Jyoti; Derynck, Joanna; Lambert, Jean-Philippe; Pearlman, Ronald E.; Fillingham, Jeffrey. (2020). Nucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila. SCIENTIFIC REPORTS. DOI: 10.1038/s41598-019-56867-0 (http://dx.doi.org/10.1038/s41598-019-56867-0)
Levesque, Sebastien; Agudelo, Daniel; Doyon, Yannick. (2020). Rewired Cas9s with Minimal Sequence Constraints. TRENDS IN PHARMACOLOGICAL SCIENCES. DOI: 10.1016/j.tips.2020.04.009 (http://dx.doi.org/10.1016/j.tips.2020.04.009)
Schaekel, Laura; Schmies, Constanze C.; Idris, Riham M.; Luo, Xihuan; Lee, Sang-Yong; Lopez, Vittoria; Mirza, Salahuddin; Vu, The Hung; Pelletier, Julie; Sevigny, Jean; Namasivayam, Vigneshwaran; Mueller, Christa E.. (2020). Nucleotide Analog ARL67156 as a Lead Structure for the Development of CD39 and Dual CD39/CD73 Ectonucleotidase Inhibitors. FRONTIERS IN PHARMACOLOGY. DOI: 10.3389/fphar.2020.01294 (http://dx.doi.org/10.3389/fphar.2020.01294)
Teixeira, Fernanda C.; Bruxel, Fernanda; Azambuja, Juliana H.; Berenguer, Alexandre M.; Stefani, Marco A.; Sevigny, Jean; Spanevello, Roselia M.; Battastini, Ana M. O.; Teixeira, Helder F.; Braganhol, Elizandra. (2020). Development and characterization of CD73-siRNA-loaded nanoemulsion: effect on C6 glioma cells and primary astrocytes. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY. DOI: 10.1080/10837450.2019.1705485 (http://dx.doi.org/10.1080/10837450.2019.1705485)
Lemay, Marie-Laurence; Maass, Sandra; Otto, Andreas; Hamel, Jeremie; Plante, Pier-Luc; Rousseau, Genevieve M.; Tremblay, Denise M.; Shi, Rong; Corbeil, Jacques; Gagne, Stephane M.; Becher, Doerte; Moineau, Sylvain. (2020). A Lactococcal Phage Protein Promotes Viral Propagation and Alters the Host Proteomic Response During Infection. VIRUSES-BASEL. DOI: 10.3390/v12080797 (http://dx.doi.org/10.3390/v12080797)
Mathieu, Aurelie; Dion, Moira; Deng, Ling; Tremblay, Denise; Moncaut, Elisabeth; Shah, Shiraz A.; Stokholm, Jakob; Krogfelt, Karen A.; Schjorring, Susanne; Bisgaard, Hans; Nielsen, Dennis S.; Moineau, Sylvain; Petit, Marie-Agnes. (2020). Virulent coliphages in 1-year-old children fecal samples are fewer, but more infectious than temperate coliphages. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-019-14042-z (http://dx.doi.org/10.1038/s41467-019-14042-z)
Kothari, Charu; Osseni, Mazid Abiodoun; Agbo, Lynda; Ouellette, Genevieve; Deraspe, Maxime; Laviolette, Francois; Corbeil, Jacques; Lambert, Jean-Philippe; Diorio, Caroline; Durocher, Francine. (2020). Machine learning analysis identifies genes differentiating triple negative breast cancers. SCIENTIFIC REPORTS. DOI: 10.1038/s41598-020-67525-1 (http://dx.doi.org/10.1038/s41598-020-67525-1)
Despres, Philippe C.; Dube, Alexandre K.; Seki, Motoaki; Yachie, Nozomu; Landry, Christian R.. (2020). Perturbing proteomes at single residue resolution using base editing. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-020-15796-7 (http://dx.doi.org/10.1038/s41467-020-15796-7)
Azambuja, J. H.; Schuh, R. S.; Michels, L. R.; Iser, I. C.; Beckenkamp, L. R.; Roliano, G. G.; Lenz, G. S.; Scholl, J. N.; Sevigny, J.; Wink, M. R.; Stefani, M. A.; Battastini, A. M. O.; Figueiro, F.; Teixeira, H. F.; Braganhol, E.. (2020). Blockade of CD73 delays glioblastoma growth by modulating the immune environment. CANCER IMMUNOLOGY IMMUNOTHERAPY. DOI: 10.1007/s00262-020-02569-w (http://dx.doi.org/10.1007/s00262-020-02569-w)
Lemay, Marie-Laurence; Moineau, Sylvain. (2020). How are genes modified? Crossbreeding, mutagenesis, and CRISPR-Cas9. GENETICALLY MODIFIED AND IRRADIATED FOOD: CONTROVERSIAL ISSUES: FACTS VERSUS PERCEPTIONS. DOI: 10.1016/B978-0-12-817240-7.00003-6 (http://dx.doi.org/10.1016/B978-0-12-817240-7.00003-6)
Cooke, Steven; Nguyen, Vivian M.; Anastakis, Dimitry; Scott, Shannon D.; Turetsky, Merritt R.; Amirfazli, Alidad; Hearn, Alison; Milton, Cynthia E.; Loewen, Laura; Smith, Eric E.; Norris, D. Ryan; Lavoie, Kim L.; Aiken, Alice; Ansari, Daniel; Antle, Alissa; Babel, Molly; Bailey, Jane; Bernstein, Daniel M.; Birnbaum, Rachel; Bourassa, Carrie; Calcagno, Antonio; Campana, Aurelie; Chen, Bing; Collins, Karen; Connelly, Catherine E.; Denov, Myriam; Dupont, Benoit; George, Eric; Gregory-Eaves, Irene; High, Steven; Hill, Josephine M.; Jackson, Philip L.; Jette, Nathalie; Jurdjevic, Mark; Kothari, Anita; Khairy, Paul; Lamoureux, Sylvie A.; Ladner, Kiera; Landry, Christian R.; Legare, Francois; Lehoux, Nadia; Leuprecht, Christian; Lieverse, Angela R.; Luczak, Artur; Mallory, Mark L.; Manning, Erin; Mazalek, Ali; Murray, Stuart J.; Newman, Lenore L.; Oosterveld, Valerie; Potvin, Patrice; Reimer-Kirkham, Sheryl; Rowsell, Jennifer; Stacey, Dawn; Tighe, Susan; Vocadlo, David J.; Wilson, Anne E.; Woolford, Andrew. (2020). Diverse perspectives on interdisciplinarity from Members of the College of the Royal Society of Canada. FACETS. DOI: 10.1139/facets-2019-0044 (http://dx.doi.org/10.1139/facets-2019-0044)
Younus, Hafiza Amna; Hameed, Abdul; Mahmood, Abid; Khan, Muhammad Siraj; Saeed, Muhammad; Batool, Farwa; Asari, Asnuzilawati; Mohamad, Habsah; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed; al-Rashida, Mariya. (2020). Sulfonylhydrazones: Design, synthesis and investigation of ectonucleotidase (ALP & e5?NT) inhibition activities. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2020.103827 (http://dx.doi.org/10.1016/j.bioorg.2020.103827)
Ferreira, Maria Tedim; Berger, Louise; Rouleau, Michele; Poirier, Guy G.. (2020). Assessment of PARP-1 Distribution in Tissues of Cynomolgus Monkeys. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. DOI: 10.1369/0022155420926022 (http://dx.doi.org/10.1369/0022155420926022)
Herman-de-Sousa, Carina; Pinheiro, Ana Rita; Paramos-de-Carvalho, Diogo; Costa, Maria Adelina; Ferreirinha, Fatima; Magalhaes-Cardoso, Teresa; Ribeiro, Severino; Pelletier, Julie; Sevigny, Jean; Correia-de-Sa, Paulo. (2020). Opposing Effects of Adenosine and Inosine in Human Subcutaneous Fibroblasts May Be Regulated by Third Party ADA Cell Providers. CELLS. DOI: 10.3390/cells9030651 (http://dx.doi.org/10.3390/cells9030651)
Zhang, Heng; Devoucoux, Maeva; Song, Xiaosheng; Li, Li; Ayaz, Gamze; Cheng, Harry; Tempel, Wolfram; Dong, Cheng; Loppnau, Peter; Cote, Jacques; Min, Jinrong. (2020). Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex. CELL REPORTS. DOI: 10.1016/j.celrep.2020.03.003 (http://dx.doi.org/10.1016/j.celrep.2020.03.003)
Braga, Luciano Gama; Cisneros, Angel F.; Mathieu, Michelle M.; Clerc, Maxime; Garcia, Pauline; Lottin, Baptiste; Garand, Chantal; Thebault, Philippe; Landry, Christian R.; Elowe, Sabine. (2020). BUBR1 Pseudokinase Domain Promotes Kinetochore PP2A-B56 Recruitment, Spindle Checkpoint Silencing, and Chromosome Alignment. CELL REPORTS. DOI: 10.1016/j.celrep.2020.108397 (http://dx.doi.org/10.1016/j.celrep.2020.108397)
Beckenkamp, L. R.; da Fontoura, D. M. S.; Korb, V. G.; de Campos, R. P.; Onzi, G. R.; Iser, I. C.; Bertoni, A. P. S.; Sevigny, J.; Lenz, G.; Wink, Marcia Rosangela. (2020). Immortalization of Mesenchymal Stromal Cells by TERT Affects Adenosine Metabolism and Impairs their Immunosuppressive Capacity. STEM CELL REVIEWS AND REPORTS. DOI: 10.1007/s12015-020-09986-5 (http://dx.doi.org/10.1007/s12015-020-09986-5)
Scholl, Juliete Nathali; Dias, Amanda de Fraga; Pizzato, Pauline Rafaela; Lopes, Daniela Vasconcelos; Jacintho Moritz, Cesar Eduardo; Farias Jandrey, Elisa Helena; Souto, Gabriele Dadalt; Colombo, Mariana; Rohden, Francieli; Sevigny, Jean; Pohlmann, Adriana Raffin; Guterres, Silvia Staniscuaski; Oliveira Battastini, Ana Maria; Figueiro, Fabricio. (2020). Characterization and antiproliferative activity of glioma-derived extracellular vesicles. NANOMEDICINE. DOI: 10.2217/nnm-2019-0431 (http://dx.doi.org/10.2217/nnm-2019-0431)
Philippe, Cecile; Levesque, Sebastien; Dion, Moira B.; Tremblay, Denise M.; Horvath, Philippe; Lueth, Natascha; Cambillau, Christian; Franz, Charles; Neve, Horst; Fremaux, Christophe; Heller, Knut J.; Moineau, Sylvain. (2020). Novel Genus of Phages Infecting Streptococcus thermophilus: Genomic and Morphological Characterization. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. DOI: 10.1128/AEM.00227-20 (http://dx.doi.org/10.1128/AEM.00227-20)
Gao, Ruimin; Naushad, Sohail; Moineau, Sylvain; Levesque, Roger; Goodridge, Lawrence; Ogunremi, Dele. (2020). Comparative genomic analysis of 142 bacteriophages infecting Salmonella enterica subsp. enterica. BMC GENOMICS. DOI: 10.1186/s12864-020-6765-z (http://dx.doi.org/10.1186/s12864-020-6765-z)
Henault, Mathieu; Marsit, Souhir; Charron, Guillaume; Landry, Christian R.. (2020). The effect of hybridization on transposable element accumulation in an undomesticated fungal species. ELIFE. DOI: 10.7554/eLife.60474 (http://dx.doi.org/10.7554/eLife.60474)
Lamaa, Assala; Humbert, Jonathan; Aguirrebengoa, Marion; Cheng, Xue; Nicolas, Estelle; Cote, Jacques; Trouche, Didier. (2020). Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation. ELIFE. DOI: 10.7554/eLife.53375 (http://dx.doi.org/10.7554/eLife.53375)
Willig, Julia Biz; Barreto Vianna, Debora Renz; Beckenkamp, Aline; Beckenkamp, Liziane Raquel; Sevigny, Jean; Wink, Marcia Rosangela; Buffon, Andreia; Pilger, Diogo Andre. (2020). Imatinib mesylate affects extracellular ATP catabolism and expression of NTPDases in a chronic myeloid leukemia cell line. PURINERGIC SIGNALLING. DOI: 10.1007/s11302-019-09686-x (http://dx.doi.org/10.1007/s11302-019-09686-x)
Aziz, Hamid; Mahmood, Abid; Zaib, Sumera; Saeed, Aamer; Shafiq, Zahid; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2020). Synthesis, characterization, in vitro tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP) inhibition studies and computational evaluation of novel thiazole derivatives. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2020.104088 (http://dx.doi.org/10.1016/j.bioorg.2020.104088)
Ullah, Saif; El-Gamal, Mohammed, I; Zaib, Sumera; Anbar, Hanan S.; Zaraei, Seyed-Omar; Sbenati, Rawan M.; Pelletier, Julie; Sevigny, Jean; Oh, Chang-Hyun; Iqbal, Jamshed. (2020). Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2020.103783 (http://dx.doi.org/10.1016/j.bioorg.2020.103783)
Andleeb, Hina; Hussain, Muzammal; Ejaz, Syeda Abida; Sevigny, Jean; Farman, Muhammad; Yasinzai, Masoom; Zhang, Jiancun; Iqbal, Jamshed; Hameed, Shahid. (2020). Synthesis and computational studies of highly selective inhibitors of human recombinant tissue non-specific alkaline phosphatase (h-TNAP): A therapeutic target against vascular calcification. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2020.103999 (http://dx.doi.org/10.1016/j.bioorg.2020.103999)
Anbar, Hanan S.; El-Gamal, Randa; Ullah, Saif; Zaraei, Seyed-Omar; al-Rashida, Mariya; Zaib, Sumera; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed; El-Gamal, Mohammed I.. (2020). Evaluation of sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as inhibitors of nucleotide pyrophosphatases/phosphodiesterases and anticancer agents. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2020.104305 (http://dx.doi.org/10.1016/j.bioorg.2020.104305)
Ashraf, Abida; Shafiq, Zahid; Jadoon, Muhammad Siraj Khan; Tahir, Muhammad Nawaz; Pelletier, Julie; Sevigny, Jean; Yaqub, Muhammad; Iqbal, Jamshed. (2020). Synthesis, Characterization, and In Silico Studies of Novel Spirooxindole Derivatives as Ecto-5′-Nucleotidase Inhibitors. ACS MEDICINAL CHEMISTRY LETTERS. DOI: 10.1021/acsmedchemlett.0c00343 (http://dx.doi.org/10.1021/acsmedchemlett.0c00343)
Mumtaz, Amara; Saeed, Kiran; Mahmood, Abid; Zaib, Sumera; Saeed, Aamer; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2020). Bisthioureas of pimelic acid and 4-methylsalicylic acid derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP): Synthesis and molecular docking studies. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2020.103996 (http://dx.doi.org/10.1016/j.bioorg.2020.103996)
Pelletier, Julie; Agonsanou, Herve; Manica, Fabiana; Lavoie, Elise G.; Salem, Mabrouka; Luyindula, Patrick; Babou Kammoe, Romuald Brice; Sevigny, Jean. (2020). A Simple and Efficient Genetic Immunization Protocol for the Production of Highly Specific Polyclonal and Monoclonal Antibodies against the Native Form of Mammalian Proteins. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms21197074 (http://dx.doi.org/10.3390/ijms21197074)
Simon, Gaelle; Berube, Christopher; Paquet-Cote, Pierre-Alexandre; Grenier, Daniel; Voyer, Normand. (2020). Preventing Candida albicans biofilm formation using aromatic-rich piperazines. BIOORGANIC & MEDICINAL CHEMISTRY. DOI: 10.1016/j.bmc.2020.115810 (http://dx.doi.org/10.1016/j.bmc.2020.115810)
Maltais, Rene; Djiemeny, Adrien Ngueta; Roy, Jenny; Barbeau, Xavier; Lambert, Jean-Philippe; Poirier, Donald. (2020). Design and synthesis of dansyl-labeled inhibitors of steroid sulfatase for optical imaging. BIOORGANIC & MEDICINAL CHEMISTRY. DOI: 10.1016/j.bmc.2020.115368 (http://dx.doi.org/10.1016/j.bmc.2020.115368)
Louphrasitthiphol, Pakavarin; Siddaway, Robert; Loffreda, Alessia; Pogenberg, Vivian; Friedrichsen, Hans; Schepsky, Alexander; Zeng, Zhiqiang; Lu, Min; Strub, Thomas; Freter, Rasmus; Lisle, Richard; Suer, Eda; Thomas, Benjamin; Schuster-Bockler, Benjamin; Filippakopoulos, Panagis; Middleton, Mark; Lu, Xin; Patton, E. Elizabeth; Davidson, Irwin; Lambert, Jean-Philippe; Wilmanns, Matthias; Steingrimsson, Eirikur; Mazza, Davide; Goding, Colin R.. (2020). Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution. MOLECULAR CELL. DOI: 10.1016/j.molcel.2020.05.025 (http://dx.doi.org/10.1016/j.molcel.2020.05.025)
Agudelo, Daniel; Carter, Sophie; Velimirovic, Minja; Duringer, Alexis; Rivest, Jean-Francois; Levesque, Sebastien; Loehr, Jeremy; Mouchiroud, Mathilde; Cyr, Denis; Waters, Paula J.; Laplante, Mathieu; Moineau, Sylvain; Goulet, Adeline; Doyon, Yannick. (2020). Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9. GENOME RESEARCH. DOI: 10.1101/gr.255414.119 (http://dx.doi.org/10.1101/gr.255414.119)
Klein, Brianna J.; Cox, Khan L.; Jang, Suk Min; Cote, Jacques; Poirier, Michael G.; Kutateladze, Tatiana G.. (2020). Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin. STRUCTURE. DOI: 10.1016/j.str.2019.10.014 (http://dx.doi.org/10.1016/j.str.2019.10.014)
Paquet-Cote, Pierre-Alexandre; Paradis, Jean-Philippe; Auger, Michele; Voyer, Normand. (2020). Crown ether modified peptides: Length and crown ring size impact on membrane interactions. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. DOI: 10.1016/j.bbamem.2020.183261 (http://dx.doi.org/10.1016/j.bbamem.2020.183261)
Kot, Witold; Olsen, Nikoline S.; Nielsen, Tue K.; Hutinet, Geoffrey; de Crecy-Lagard, Valerie; Cui, Liang; Dedon, Peter C.; Carstens, Alexander B.; Moineau, Sylvain; Swairjo, Manal A.; Hansen, Lars H.. (2020). Detection of preQ0 deazaguanine modifications in bacteriophage CAjan DNA using Nanopore sequencing reveals same hypermodification at two distinct DNA motifs. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkaa735 (http://dx.doi.org/10.1093/nar/gkaa735)
Kiepas, Alex; Voorand, Elena; Senecal, Julien; Ahn, Ryuhjin; Annis, Matthew G.; Jacquet, Kevin; Tali, George; Bisson, Nicolas; Ursini-Siegel, Josie; Siegel, Peter M.; Brown, Claire M.. (2020). The SHCA adapter protein cooperates with lipoma-preferred partner in the regulation of adhesion dynamics and invadopodia formation. JOURNAL OF BIOLOGICAL CHEMISTRY. DOI: 10.1074/jbc.RA119.011903 (http://dx.doi.org/10.1074/jbc.RA119.011903)
Pham, Van Dung; To, Tuan Anh; Gagne-Thivierge, Cynthia; Couture, Manon; Lague, Patrick; Yao, Deqiang; Picard, Marie-Eve; Lortie, Louis-Andre; Attere, Sabrina A.; Zhu, Xiaojun; Levesque, Roger C.; Charette, Steve J.; Shi, Rong. (2020). Structural insights into the putative bacterial acetylcholinesterase ChoE and its substrate inhibition mechanism. JOURNAL OF BIOLOGICAL CHEMISTRY. DOI: 10.1074/jbc.RA119.011809 (http://dx.doi.org/10.1074/jbc.RA119.011809)
Manenda, Mahder S.; Picard, Marie-Eve; Zhang, Liping; Cyr, Normand; Zhu, Xiaojun; Barma, Julie; Pascal, John M.; Couture, Manon; Zhang, Changsheng; Shi, Rong. (2020). Structural analyses of the Group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations. JOURNAL OF BIOLOGICAL CHEMISTRY. DOI: 10.1074/jbc.RA119.011212 (http://dx.doi.org/10.1074/jbc.RA119.011212)
Kaplan, Andrew; Andrei, Sebastian A.; Altena, Anna van Regteren; Simas, Tristan; Banerjee, Sara L.; Kato, Nobuo; Bisson, Nicolas; Higuchi, Yusuke; Ottmann, Christian; Fournier, Alyson E.. (2020). Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth. CELL CHEMICAL BIOLOGY. DOI: 10.1016/j.chembiol.2020.02.010 (http://dx.doi.org/10.1016/j.chembiol.2020.02.010)
Tchara, Pata-Eting Kougnassoukou; Filippakopoulos, Panagis; Lambert, Jean-Philippe. (2020). Emerging tools to investigate bromodomain functions. METHODS. DOI: 10.1016/j.ymeth.2019.11.003 (http://dx.doi.org/10.1016/j.ymeth.2019.11.003)
Dos Santos, Alexsandro; Elowe, Sabine. (2020). Moonlighting at the Centrosome: RXRα Turns to Plk1. DEVELOPMENTAL CELL. DOI: 10.1016/j.devcel.2020.11.027 (http://dx.doi.org/10.1016/j.devcel.2020.11.027)
Ahmad, Haseen; Ullah, Saif; Rahman, Fouzia; Saeed, Aamer; Pelletier, Julie; Sevigny, Jean; Hassan, Abbas; Iqbal, Jamshed. (2020). Synthesis of biphenyl oxazole derivatives via Suzuki coupling and biological evaluations as nucleotide pyrophosphatase/phosphodiesterase-1 and-3 inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. DOI: 10.1016/j.ejmech.2020.112759 (http://dx.doi.org/10.1016/j.ejmech.2020.112759)
Zarrouk, Karima; Van Dung Pham; Piret, Jocelyne; Shi, Rong; Boivin, Guy. (2020). Hypersusceptibility of Human Cytomegalovirus to Foscarnet Induced by Mutations in Helices K and P of the Viral DNA Polymerase. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. DOI: 10.1128/AAC.01910-19 (http://dx.doi.org/10.1128/AAC.01910-19)
Lachance, Gabriel P.; Niyonambaza, Shimwe Dominique; Boisselier, Elodie; Boukadoum, Mounir; Miled, Amine. (2020). Critical Comparison of Sequential and Non-sequential Modes Usage for the Design of a Czerny-Turner Spectrometer. 2020 18TH IEEE INTERNATIONAL NEW CIRCUITS AND SYSTEMS CONFERENCE (NEWCAS'20). DOI: 10.1109/newcas49341.2020.9159788 (http://dx.doi.org/10.1109/newcas49341.2020.9159788)
Dion, Moira B.; Oechslin, Frank; Moineau, Sylvain. (2020). Phage diversity, genomics and phylogeny. NATURE REVIEWS MICROBIOLOGY. DOI: 10.1038/s41579-019-0311-5 (http://dx.doi.org/10.1038/s41579-019-0311-5)
Makarova, Kira S.; Wolf, Yuri, I; Iranzo, Jaime; Shmakov, Sergey A.; Alkhnbashi, Omer S.; Brouns, Stan J. J.; Charpentier, Emmanuelle; Cheng, David; Haft, Daniel H.; Horvath, Philippe; Moineau, Sylvain; Mojica, Francisco J. M.; Scott, David; Shah, Shiraz A.; Siksnys, Virginijus; Terns, Michael P.; Venclovas, Ceslovas; White, Malcolm F.; Yakunin, Alexander F.; Yan, Winston; Zhang, Feng; Garrett, Roger A.; Backofen, Rolf; van der Oost, John; Barrangou, Rodolphe; Koonin, Eugene, V. (2020). Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants. NATURE REVIEWS MICROBIOLOGY. DOI: 10.1038/s41579-019-0299-x (http://dx.doi.org/10.1038/s41579-019-0299-x)
Mosterd, Cas; Moineau, Sylvain. (2020). Characterization of a Type II-A CRISPR-Cas System in Streptococcus mutans. MSPHERE. DOI: 10.1128/mSphere.00235-20 (http://dx.doi.org/10.1128/mSphere.00235-20)
Yousfi, Khadidja; Usongo, Valentine; Berry, Chrystal; Khan, Rufaida H.; Tremblay, Denise M.; Moineau, Sylvain; Mulvey, Michael R.; Doualla-Bell, Florence; Fournier, Eric; Nadon, Celine; Goodridge, Lawrence; Bekal, Sadjia. (2020). Source Tracking Based on Core Genome SNV and CRISPR Typing ofSalmonella entericaSerovar Heidelberg Isolates Involved in Foodborne Outbreaks in Quebec, 2012. FRONTIERS IN MICROBIOLOGY. DOI: 10.3389/fmicb.2020.01317 (http://dx.doi.org/10.3389/fmicb.2020.01317)
de Melo, Alessandra G.; Rousseau, Genevieve M.; Tremblay, Denise M.; Labrie, Simon J.; Moineau, Sylvain. (2020). DNAtandemrepeats contribute to the genetic diversity ofBrevibacterium aurantiacumphages. ENVIRONMENTAL MICROBIOLOGY. DOI: 10.1111/1462-2920.15113 (http://dx.doi.org/10.1111/1462-2920.15113)
Farnos, Omar; Venereo-Sanchez, Alina; Xu, Xingge; Chan, Cindy; Dash, Shantoshini; Chaabane, Hanan; Sauvageau, Janelle; Brahimi, Fouad; Saragovi, Uri; Leclerc, Denis; Kamen, Amine A.. (2020). Rapid High-Yield Production of Functional SARS-CoV-2 Receptor Binding Domain by Viral and Non-Viral Transient Expression for Pre-Clinical Evaluation. VACCINES. DOI: 10.3390/vaccines8040654 (http://dx.doi.org/10.3390/vaccines8040654)
Langley, Joanne; Pastural, Elodie; Halperin, Scott; McNeil, Shelly; ElSherif, May; MacKinnon-Cameron, Donna; Ye, Lingyun; Grange, Cecile; Thibodeau, Valerie; Cailhier, Jean-Francois; Lapointe, Rejean; McElhaney, Janet; Martin, Luis; Bolduc, Marilene; Laliberte-Gagne, Marie-Eve; Leclerc, Denis; Savard, Pierre. (2020). A Randomized Controlled Study to Evaluate the Safety and Reactogenicity of a Novel rVLP-Based Plant Virus Nanoparticle Adjuvant Combined with Seasonal Trivalent Influenza Vaccine Following Single Immunization in Healthy Adults 18-50 Years of Age. VACCINES. DOI: 10.3390/vaccines8030393 (http://dx.doi.org/10.3390/vaccines8030393)
Mangion, Mathias; Gelinas, Jean-Francois; Gashti, Anahita Bakhshi Zadeh; Azizi, Hiva; Kiesslich, Sascha; Nassoury, Nasha; Chahal, Parminder S.; Kobinger, Gary; Gilbert, Renald; Garnier, Alain; Gaillet, Bruno; Kamen, Amine. (2020). Evaluation of novel HIV vaccine candidates using recombinant vesicular stomatitis virus vector produced in serum-free Vero cell cultures. VACCINE. DOI: 10.1016/j.vaccine.2020.10.058 (http://dx.doi.org/10.1016/j.vaccine.2020.10.058)
Chesnel, Franck; Couturier, Anne; Alusse, Adrien; Gagne, Jean-Philippe; Poirier, Guy G.; Jean, Dominique; Boisvert, Francois-Michel; Hascoet, Pauline; Paillard, Luc; Arlot-Bonnemains, Yannick; Le Goff, Xavier. (2020). The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation. PLOS GENETICS. DOI: 10.1371/journal.pgen.1009183 (http://dx.doi.org/10.1371/journal.pgen.1009183)
Fages, Jeremie; Chailleux, Catherine; Humbert, Jonathan; Jang, Suk-Min; Loehr, Jeremy; Lambert, Jean-Philippe; Cote, Jacques; Trouche, Didier; Canitrot, Yvan. (2020). JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage. PLOS GENETICS. DOI: 10.1371/journal.pgen.1008511 (http://dx.doi.org/10.1371/journal.pgen.1008511)
Fijarczyk, Anna; Henault, Mathieu; Marsit, Souhir; Charron, Guillaume; Fischborn, Tobias; Nicole-Labrie, Luc; Landry, Christian R.. (2020). The Genome Sequence of the Jean-Talon Strain, an Archeological Beer Yeast from Quebec, Reveals Traces of Adaptation to Specific Brewing Conditions. G3-GENES GENOMES GENETICS. DOI: 10.1534/g3.120.401149 (http://dx.doi.org/10.1534/g3.120.401149)
Cornuault, Jeffrey K.; Moineau, Sylvain. (2020). A Jumbo Formation in the Viral Game Plan. CRISPR JOURNAL. DOI: 10.1089/crispr.2020.29082.jco (http://dx.doi.org/10.1089/crispr.2020.29082.jco)
Hallin, Johan; Cisneros, Angel F.; Henault, Mathieu; Fijarczyk, Anna; Dandage, Rohan; Bautista, Carla; Landry, Christian R.. (2020). Similarities in biological processes can be used to bridge ecology and molecular biology. EVOLUTIONARY APPLICATIONS. DOI: 10.1111/eva.12961 (http://dx.doi.org/10.1111/eva.12961)
Bleuven, Clara; Nguyen, Guillaume Q.; Despres, Philippe C.; Filteau, Marie; Landry, Christian R.. (2020). Competition experiments in a soil microcosm reveal the impact of genetic and biotic factors on natural yeast populations. ISME JOURNAL. DOI: 10.1038/s41396-020-0612-8 (http://dx.doi.org/10.1038/s41396-020-0612-8)
Afzal, Saira; Zaib, Sumera; Jafari, Behzad; Langer, Peter; Lecka, Joanna; Sevigny, Jean; Iqbal, Jamshed. (2020). Highly Potent and Selective Ectonucleoside Triphosphate Diphosphohydrolase (ENTPDase1, 2, 3 and 8) Inhibitors Having 2-substituted-7-trifluoromethyl-thiadiazolopyrimidones Scaffold. MEDICINAL CHEMISTRY. DOI: 10.2174/1573406415666190614095821 (http://dx.doi.org/10.2174/1573406415666190614095821)
Hessenauer, Pauline; Fijarczyk, Anna; Martin, Helene; Prunier, Julien; Charron, Guillaume; Chapuis, Jerome; Bernier, Louis; Tanguay, Philippe; Hamelin, Richard C.; Landry, Christian R.. (2020). Hybridization and introgression drive genome evolution of Dutch elm disease pathogens. NATURE ECOLOGY & EVOLUTION. DOI: 10.1038/s41559-020-1133-6 (http://dx.doi.org/10.1038/s41559-020-1133-6)
Tao, Hirotaka; Lambert, Jean-Philippe; Yung, Theodora M.; Zhu, Min; Hahn, Noah A.; Li, Danyi; Lau, Kimberly; Sturgeon, Kendra; Puviindran, Vijitha; Zhang, Xiaoyun; Gong, Wuming; Chen, Xiao Xiao; Anderson, Gregory; Garry, Daniel J.; Henkelman, R. Mark; Sun, Yu; Iulianella, Angelo; Kawakami, Yasuhiko; Gingras, Anne-Claude; Hui, Chi-chung; Hopyan, Sevan. (2020). IRX3/5 regulate mitotic chromatid segregation and limb bud shape. DEVELOPMENT. DOI: 10.1242/dev.180042 (http://dx.doi.org/10.1242/dev.180042)
Martial, Benjamin; Raiche-Marcoux, Gabrielle; Lefevre, Thierry; Audet, Pierre; Voyer, Normand; Auger, Michele. (2020). Structure of a Parkinson's Disease-Involved α-Synuclein Peptide Is Modulated by Membrane Composition and Physical State. JOURNAL OF PHYSICAL CHEMISTRY B. DOI: 10.1021/acs.jpcb.0c00945 (http://dx.doi.org/10.1021/acs.jpcb.0c00945)
St-Gelais, Jacob; Denavit, Vincent; Giguere, Denis. (2020). Efficient synthesis of a galectin inhibitor clinical candidate (TD139) using a Payne rearrangement/azidation reaction cascade. ORGANIC & BIOMOLECULAR CHEMISTRY. DOI: 10.1039/d0ob00910e (http://dx.doi.org/10.1039/d0ob00910e)
Gonay, Marie; Batisse, Chloe; Paquin, Jean-Francois. (2020). Synthesis of Acyl Fluorides from Carboxylic Acids Using NaF-Assisted Deoxofluorination with XtalFluor-E. JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1021/acs.joc.0c01377 (http://dx.doi.org/10.1021/acs.joc.0c01377)
Laine, Danny; Denavit, Vincent; Lessard, Olivier; Carrier, Laurie; Fecteau, Charles-Emile; Johnson, Paul A.; Giguere, Denis. (2020). Fluorine effect in nucleophilic fluorination at C4 of 1,6-anhydro-2,3-dideoxy-2,3-difluoro-β-D-hexopyranose. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.3762/bjoc.16.237 (http://dx.doi.org/10.3762/bjoc.16.237)
Gilbert, Audrey; Langowski, Pauline; Delgado, Marine; Chabaud, Laurent; Pucheault, Mathieu; Paquin, Jean-Francois. (2020). Amine-borane complex-initiated SF5Cl radical addition on alkenes and alkynes. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.3762/bjoc.16.256 (http://dx.doi.org/10.3762/bjoc.16.256)
Yan, Xiaolin; Noel, Francis; Marcotte, Isabelle; DeWolf, Christine E.; Warschawski, Dror E.; Boisselier, Elodie. (2020). AHNAK C-Terminal Peptide Membrane Binding-Interactions between the Residues 5654-5673 of AHNAK and Phospholipid Monolayers and Bilayers. LANGMUIR. DOI: 10.1021/acs.langmuir.9b02973 (http://dx.doi.org/10.1021/acs.langmuir.9b02973)
Kanwal, Afshan; Ullah, Saif; Ahmad, Matloob; Pelletier, Julie; Aslam, Sana; Sultan, Sadia; Sevigny, Jean; Iqbal, Mazhar; Iqbal, Jamshed. (2020). Synthesis and Nucleotide Pyrophosphatase/Phosphodiesterase Inhibition Studies of Carbohydrazides Based on Benzimidazole-Benzothiazine Skeleton. CHEMISTRYSELECT. DOI: 10.1002/slct.202003479 (http://dx.doi.org/10.1002/slct.202003479)
Houle, Camille; Savoie, Paul R.; Davies, Clotilde; Jardel, Damien; Champagne, Pier Alexandre; Bibal, Brigitte; Paquin, Jean-Francois. (2020). Thiourea-Catalyzed C-F Bond Activation: Amination of Benzylic Fluorides. CHEMISTRY-A EUROPEAN JOURNAL. DOI: 10.1002/chem.202001905 (http://dx.doi.org/10.1002/chem.202001905)
Drouin, Myriam; Wadhwani, Parvesh; Grage, Stephan L.; Buerck, Jochen; Reichert, Johannes; Tremblay, Sebastien; Mayer, Marie Sabine; Diel, Christian; Staub, Alexander; Paquin, Jean-Francois; Ulrich, Anne S.. (2020). Monofluoroalkene-Isostere as a 19F NMR Label for the Peptide Backbone: Synthesis and Evaluation in Membrane-Bound PGLa and (KIGAKI)3. CHEMISTRY-A EUROPEAN JOURNAL. DOI: 10.1002/chem.201905054 (http://dx.doi.org/10.1002/chem.201905054)
St-Gelais, Jacob; Cote, Emilie; Laine, Danny; Johnson, Paul A.; Giguere, Denis. (2020). Addressing the Structural Complexity of Fluorinated Glucose Analogues: Insight into Lipophilicities and Solvation Effects. CHEMISTRY-A EUROPEAN JOURNAL. DOI: 10.1002/chem.202002825 (http://dx.doi.org/10.1002/chem.202002825)
Cloutier, Melissa; Mamone, Marius; Paquin, Jean-Francois. (2020). Drastic fluorine effect: complete reversal of the selectivity in the Au-catalyzed hydroalkoxylation reaction of fluorinated haloalkynes. CHEMICAL COMMUNICATIONS. DOI: 10.1039/d0cc02009e (http://dx.doi.org/10.1039/d0cc02009e)
Varano, Flavia; Catarzi, Daniela; Vincenzi, Fabrizio; Pasquini, Silvia; Pelletier, Julie; Rangel Fietto, Juliana Lopes; Gelsleichter, Nicolly Espindola; Sarlandie, Marine; Guilbaud, Audrey; Sevigny, Jean; Varani, Katia; Colotta, Vittoria. (2020). Structural investigation on thiazolo [5,4-d]pyrimidines to obtain dual-acting blockers of CD73 and adenosine A2A receptor as potential antitumor agents. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. DOI: 10.1016/j.bmcl.2020.127067 (http://dx.doi.org/10.1016/j.bmcl.2020.127067)
Spinelli, Silvia; Tremblay, Denise; Moineau, Sylvain; Cambillau, Christian; Goulet, Adeline. (2020). Structural Insights into Lactococcal Siphophage p2 Baseplate Activation Mechanism. VIRUSES-BASEL. DOI: 10.3390/v12080878 (http://dx.doi.org/10.3390/v12080878)