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2025
Verret, Laurianne; Burchell-Reyes, Kelly ; Morin, Jean-Francois ; Paquin, Jean-Francois. (2025) Exploration of 2-(pentafluoro-λ6-sulfanyl)ethane-1-sulfonyl chloride as a novel pentafluorosulfanylation reagent. JOURNAL OF FLUORINE CHEMISTRY. DOI 10.1016/j.jfluchem.2024.110387 (http://dx.doi.org/10.1016/j.jfluchem.2024.110387)
Bahadori, Sam; Leclerc, Christina; St-Gelais, Jacob; Poulin, Guillaume; Giguere, Denis. (2025) Catalyst-Controlled, Site-Selective Functionalization of Levoglucosan Analogues Mediated by Chiral Zinc Diamine Complexes. JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1021/acs.joc.4c02681 (http:dx.doi.org/10.1021/acs.joc.4c02681)
Prifti, Diogjena Katerina; Lauzier, Annie; Garand, Chantal; Calvo, Eva; Devillers, Romain; Roy, Suparba; Dos Santos, Alexsandro; Descombes, Laurence; Trudel, Benjamin; Laplante, Mathieu; Bordeleau, Francois; Elowe, Sabine. (2025) ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression. JOURNAL OF CELL BIOLOGY. DOI: 10.1083/jcb.202311194 (http:dx.doi.org/10.1083/jcb.202311194)
Mamjoud, Amal; Zirah, Severine; Biron, Eric; Fliss, Omar; Fliss, Ismail. (2025) In Vitro Insights into Bacteriocin-Mediated Modulation of Chicken Cecal Microbiota. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI : 10.3390/ijms26020755 (http:dx.doi.org/10.3390/ijms26020755)
Berger, Marie-Rose Ouellet-Du; Bouillon, Jean-Philippe; Paquin, Jean-Francois. (2025) Exploration towards the bromopentafluorosulfanylation reaction of terminal alkynes. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2024.110386 (http:dx.doi.org/10.1016/j.jfluchem.2024.110386)
Provencher, Luc; Nartey, Wilson; Brownlee, Peter M.; Atkins, Austin W.; Gagne, Jean-Philippe; Baudrier, Lou; Ting, Nicholas S. Y.;Piett, Cortt G.; Fang, Shujuan; Pearson, Dustin D.; Moore, Shaun; illon, Pierre; Nagel, Zachary D.; Poirier, Guy G.; Williams, Gareth J. ; Goodarzi, Aaron A. (2025) CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-025-56085-5 (http:dx.doi.org/10.1038/s41467-025-56085-5)
Kumar, Kiran; Arnold, Alexandre A.; Gauthier, Raphael; Mamone, Marius; Paquin, Jean-Francois; Warschawski, Dror E.; Marcotte, Isabelle. (2025) Simultaneous assessment of membrane bilayer structure and drug insertion by 19F solid-state NMR. BIOPHYSICAL JOURNAL. DOI: 10.1016/j.bpj.2024.11.3319 (http:dx.doi.org/10.1016/j.bpj.2024.11.3319)
A multivalent engagement of ENL with MOZ.2024
Belguesmia, Yanath; Guay, Louis-David; Teiar, Radja; Rahman, Md Ramim Tanver; Dussert, Elodie; Biron, Eric; Drider, Djamel. (2024). Synthesis, antimicrobial activity, and mechanistic studies of enterocin DD14, a leaderless two-peptide bacteriocin. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. DOI: 10.1016/j.ijbiomac.2024.135716 (http://dx.doi.org/10.1016/j.ijbiomac.2024.135716)
Berger, Alice; Pedersen, Jannie; Kowatsch, Monika M.; Scholte, Florine; Lafrance, Marc-Alexandre; Azizi, Hiva; Li, Yue; Gomez, Alejandro; Wade, Matthew; Fausther-Bovendo, Hugues; de la Vega, Marc-Antoine; Jelinski, Joseph; Babuadze, George; Nepveu-Traversy, Marie-Edith; Lamarre, Claude; Racine, Trina; Kang, Chil-Yong; Gaillet, Bruno; Garnier, Alain; Gilbert, Renald; Kamen, Amine; Yao, Xiao-Jian; Fowke, Keith R.; Arts, Eric; Kobinger, Gary. (2024). Impact of Recombinant VSV-HIV Prime, DNA-Boost Vaccine Candidates on Immunogenicity and Viremia on SHIV-Infected Rhesus Macaques. VACCINES. DOI: 10.3390/vaccines12040369 (http://dx.doi.org/10.3390/vaccines12040369)
Bergeron, Catherine; Berube, Christopher; Lamb, Henry; Koda, Yasuko; Craik, David J.; Henriques, Sonia Troeira; Voyer, Normand; Lawrence, Nicole. (2024). Analogs of Cyclic Peptide Mortiamide-D From Marine Fungi Have Improved Membrane Permeability and Kill Drug-Resistant Melanoma Cells. PEPTIDE SCIENCE. DOI: 10.1002/pep2.24380 (http://dx.doi.org/10.1002/pep2.24380)
Bahadori, Sam; Archambault, Marie-Jeanne; Sebastiao, Mathew; Bourgault, Steve; Giguere, Denis. (2024). Convergent Synthesis of a Group B Streptococcus Type III Epitope Toward a Semisynthetic Carbohydrate-Based Vaccine. JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1021/acs.joc.4c01216 (http://dx.doi.org/10.1021/acs.joc.4c01216)
Yokoyama, Akihiko; Niida, Hiroyuki; Kutateladze, Tatiana G.; Cote, Jacques. (2024). HBO1, a MYSTerious KAT and its links to cancer. BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS. DOI: 10.1016/j.bbagrm.2024.195045 (http://dx.doi.org/10.1016/j.bbagrm.2024.195045)
Alzahrani, Abdullah Yahya Abdullah; Hameed, Abdul; Khan, Abdul Rehman; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2024). Design, synthesis and in vitro evaluation of novel sulfonylurea and sulfonylthiourea as ectonucleotidases inhibitors. RESULTS IN CHEMISTRY. DOI: 10.1016/j.rechem.2024.101548 (http://dx.doi.org/10.1016/j.rechem.2024.101548)
Garcia-Vela, Sara; Guay, Louis-David; Rahman, Md Ramim Tanver; Biron, Eric; Torres, Carmen; Fliss, Ismail. (2024). Antimicrobial Activity of Synthetic Enterocins A, B, P, SEK4, and L50, Alone and in Combinations, against Clostridium perfringens. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms25031597 (http://dx.doi.org/10.3390/ijms25031597)
Devillers, Romain; dos Santos, Alexsandro; Destombes, Quentin; Laplante, Mathieu; Elowe, Sabine. (2024). Recent insights into the causes and consequences of chromosome mis-segregation. ONCOGENE. DOI: 10.1038/s41388-024-03163-5 (http://dx.doi.org/10.1038/s41388-024-03163-5)
Zhang, Qianyi E.; Lindenberger, Jared; Parsons, Ruth J.; Thakur, Bhishem; Parks, Rob; Park, Chan Soo; Huang, Xiao; Sammour, Salam; Janowska, Katarzyna; Spence, Taylor N.; Edwards, Robert J.; Martin, Mitchell; Williams, Wilton B.; Gobeil, Sophie; Montefiori, David C.; Korber, Bette; Saunders, Kevin O.; Haynes, Barton F.; Henderson, Rory; Acharya, Priyamvada. (2024). SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition. MOLECULAR CELL. DOI: 10.1016/j.molcel.2024.06.028 (http://dx.doi.org/10.1016/j.molcel.2024.06.028)
Wu, Xiangni; Chen, Pin-, I; Whitener, Robert L.; MacDougall, Matthew S.; Coykendall, Vy M. N.; Yan, Hao; Kim, Yong Bin; Harper, William; Pathak, Shiva; Iliopoulou, Bettina P.; Hestor, Allison; Saunders, Diane C.; Spears, Erick; Sevigny, Jean; Maahs, David M.; Basina, Marina; Sharp, Seth A.; Gloyn, Anna L.; Powers, Alvin C.; Kim, Seung K.; Jensen, Kent P.; Meyer, Everett H.. (2024). CD39 delineates chimeric antigen receptor regulatory T cell subsets with distinct cytotoxic & regulatory functions against human islets. FRONTIERS IN IMMUNOLOGY. DOI: 10.3389/fimmu.2024.1415102 (http://dx.doi.org/10.3389/fimmu.2024.1415102)
Kumar, Kiran; Arnold, Alexandre A.; Gauthier, Raphael; Mamone, Marius; Paquin, Jean-Francois; Warschawski, Dror E.; Marcotte, Isabelle. (2024). 19F solid-state NMR approaches to probe antimicrobial peptide interactions with membranes in whole cells. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. DOI: 10.1016/j.bbamem.2023.184269 (http://dx.doi.org/10.1016/j.bbamem.2023.184269)
Hossain, M. Iqbal; Lee, Jun Hee; Gagne, Jean-Philippe; Khan, Junaid; Poirier, Guy G.; King, Peter H.; Dawson, Valina L.; Dawson, Ted M.; Andrabi, Shaida A.. (2024). Poly(ADP-ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation. FASEB JOURNAL. DOI: 10.1096/fj.202302559R (http://dx.doi.org/10.1096/fj.202302559R)
Larnac, Eloise; Methot, Sebastien; Pelchat, Frederic; Millette, Marc-Antoine; Montoni, Alicia; Salesse, Christian; Haydont, Valerie; Marrot, Laurent; Rochette, Patrick J.. (2024). Synergistic Toxicity of Pollutant and Ultraviolet Exposure from a Mitochondrial Perspective. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms25179146 (http://dx.doi.org/10.3390/ijms25179146)
Tasleem, Mussarat; Pelletier, Julie; Sevigny, Jean; Hussain, Zahid; Khan, Ajmal; Al-Harrasi, Ahmed; El-kott, Attalla F.; Taslimi, Parham; Negm, Sally; Shafiq, Zahid; Iqbal, Jamshed. (2024). Synthesis, in vitro, and in silico studies of morpholine-based thiosemicarbazones as ectonucleotide pyrophosphatase/ phosphodiesterase-1 and-3 inhibitors. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. DOI: 10.1016/j.ijbiomac.2024.131068 (http://dx.doi.org/10.1016/j.ijbiomac.2024.131068)
Dion, Moira B.; Shah, Shiraz A.; Deng, Ling; Thorsen, Jonathan; Stokholm, Jakob; Krogfelt, Karen A.; Schjorring, Susanne; Horvath, Philippe; Allard, Antoine; Nielsen, Dennis S.; Petit, Marie-Agnes; Moineau, Sylvain. (2024). Escherichia coli CRISPR arrays from early life fecal samples preferentially target prophages. ISME JOURNAL. DOI: 10.1093/ismejo/wrae005 (http://dx.doi.org/10.1093/ismejo/wrae005)
Ye, Danrong; Nguyen, Phuong Trang; Bourgault, Steve; Couture, Manon. (2024). The heme binding protein ChuX is a regulator of heme degradation by the ChuS protein in Escherichia coli O157:H7. JOURNAL OF INORGANIC BIOCHEMISTRY. DOI: 10.1016/j.jinorgbio.2024.112575 (http://dx.doi.org/10.1016/j.jinorgbio.2024.112575)
Gaurav, Nitika; Kanai, Akinori; Lachance, Catherine; Cox, Khan L.; Liu, Jiuyang; Grzybowski, Adrian T.; Saksouk, Nehme; Klein, Brianna J.; Komata, Yosuke; Asada, Shuhei; Ruthenburg, Alexander J.; Poirier, Michael G.; Cote, Jacques; Yokoyama, Akihiko; Kutateladze, Tatiana G.. (2024). Guiding the HBO1 complex function through the JADE subunit. NATURE STRUCTURAL & MOLECULAR BIOLOGY. DOI: 10.1038/s41594-024-01245-2 (http://dx.doi.org/10.1038/s41594-024-01245-2)
Collin, Vanessa; Biquand, Elise; Tremblay, Vincent; Lavoie, Elise G.; Blondeau, Andreanne; Gravel, Annie; Galloy, Maxime; Lashgari, Anahita; Dessapt, Julien; Cote, Jacques; Flamand, Louis; Fradet-Turcotte, Amelie. (2024). The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling. EMBO REPORTS. DOI: 10.1038/s44319-023-00035-z (http://dx.doi.org/10.1038/s44319-023-00035-z)
Ashour, Kholoud; Sali, Sujitha; Aldoukhi, Ali H.; Hall, Derek; Mubaid, Souad; Busque, Sandrine; Lian, Xian Jin; Gagne, Jean-Philippe; Khattak, Shahryar; Di Marco, Sergio; Poirier, Guy G.; Gallouzi, Imed-Eddine. (2024). pADP-ribosylation regulates the cytoplasmic localization, cleavage, and pro-apoptotic function of HuR. LIFE SCIENCE ALLIANCE. DOI: 10.26508/lsa.202302316 (http://dx.doi.org/10.26508/lsa.202302316)
Bradley, David; Garand, Chantal; Belda, Hugo; Gagnon-Arsenault, Isabelle; Treeck, Moritz; Elowe, Sabine; Landry, Christian R.. (2024). The substrate quality of CK2 target sites has a determinant role on their function and evolution. CELL SYSTEMS. DOI: 10.1016/j.cels.2024.05.005 (http://dx.doi.org/10.1016/j.cels.2024.05.005)
Fliss, Omar; Guay, Louis-David; Fliss, Ismail; Biron, Eric. (2024). Synthesis and structure-activity study of the antimicrobial lipopeptide brevibacillin. RSC MEDICINAL CHEMISTRY. DOI: 10.1039/d4md00612g (http://dx.doi.org/10.1039/d4md00612g)
Hosseini, Nava; Chehreghani, Mahdi; Moineau, Sylvain; Charette, Steve J.. (2024). Centroid of the bacterial growth curves: a metric to assess phage efficiency. COMMUNICATIONS BIOLOGY. DOI: 10.1038/s42003-024-06379-z (http://dx.doi.org/10.1038/s42003-024-06379-z)
Lessard, Olivier; Laine, Danny; Giguere, Denis. (2024). Polyhalogenated Carbohydrates: Synthesis and Applications of Sugar Halides from Fluorine to Iodine. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1002/ejoc.202400120 (http://dx.doi.org/10.1002/ejoc.202400120)
Gandon, Sylvain; Guillemet, Martin; Gatchitch, Francois; Nicot, Antoine; Renaud, Ariane C.; Tremblay, Denise M.; Moineau, Sylvain. (2024). Building pyramids against the evolutionary emergence of pathogens. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. DOI: 10.1098/rspb.2023.1529 (http://dx.doi.org/10.1098/rspb.2023.1529)
Sorroza-Martinez, Luis; Pelletier, Mia; Guay, David; Gaillet, Bruno. (2024). Recent Advances in Therapeutics and Manufacturing Processes of Recombinant Adeno-Associated Virus for the Treatment of Lung Diseases. CURRENT GENE THERAPY. DOI: 10.2174/0115665232294935240826061311 (http://dx.doi.org/10.2174/0115665232294935240826061311)
Lachance, Gabriel P.; Chamelot, Guillaume; Morin, Jean-Francois; Boisselier, Elodie; Boukadoum, Mounir; Miled, Amine. (2024). Compact Poly/Monochromatic Colorimetric Sensing System With Integrated Microfluidic Sampler. IEEE SENSORS JOURNAL. DOI: 10.1109/JSEN.2024.3442553 (http://dx.doi.org/10.1109/JSEN.2024.3442553)
Kammoe, Romuald Brice Babou; Sevigny, Jean. (2024). Extracellular nucleotides in smooth muscle contraction. BIOCHEMICAL PHARMACOLOGY. DOI: 10.1016/j.bcp.2023.116005 (http://dx.doi.org/10.1016/j.bcp.2023.116005)
Henault, Mathieu; Marsit, Souhir; Charron, Guillaume; Landry, Christian R.. (2024). The genomic landscape of transposable elements in yeast hybrids is shaped by structural variation and genotype-specific modulation of transposition rate. ELIFE. DOI: 10.7554/eLife.89277 (http://dx.doi.org/10.7554/eLife.89277)
Rivest, Jean-Francois; Carter, Sophie; Goupil, Claudia; Anterieux, Penelope; Cyr, Denis; Ung, Roth-Visal; Dal Soglio, Dorothee; Mac-Way, Fabrice; Waters, Paula J.; Paganelli, Massimiliano; Doyon, Yannick. (2024). In vivo dissection of the mouse tyrosine catabolic pathway with CRISPR-Cas9 identifies modifier genes affecting hereditary tyrosinemia type 1. GENETICS. DOI: 10.1093/genetics/iyae139 (http://dx.doi.org/10.1093/genetics/iyae139)
Rouleau, Francois D.; Dube, Alexandre K.; Gagnon-Arsenault, Isabelle; Dibyachintan, Soham; Pageau, Alicia; Despres, Philippe C.; Lague, Patrick; Landry, Christian R.. (2024). Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate. PLOS GENETICS. DOI: 10.1371/journal.pgen.1011252 (http://dx.doi.org/10.1371/journal.pgen.1011252)
Bourguignon, Lea; Hetu-Arbour, Roxann; Charpentier, Tania; Bolduc, Marilene; Leclerc, Denis; Heinonen, Krista M.; Lamarre, Alain. (2024). Systemic administration of a viral nanoparticle neoadjuvant prevents lung metastasis development through emergency myelopoiesis. ONCOIMMUNOLOGY. DOI: 10.1080/2162402X.2024.2429846 (http://dx.doi.org/10.1080/2162402X.2024.2429846)
Champeil, Juliette; Mangion, Mathias; Gilbert, Renald; Gaillet, Bruno. (2024). Improved Manufacturing Methods of Extracellular Vesicles Pseudotyped with the Vesicular Stomatitis Virus Glycoprotein. MOLECULAR BIOTECHNOLOGY. DOI: 10.1007/s12033-023-01007-3 (http://dx.doi.org/10.1007/s12033-023-01007-3)
Mastalerz, Vincent; Verret, Laurianne; Paquin, Jean-Francois. (2024). Synthesis of 2-(Pentafluoro-λ6-sulfanyl)acetamides and Impact of the Fluorinated Group on the Lipophilicity. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1002/ejoc.202400956 (http://dx.doi.org/10.1002/ejoc.202400956)
Binet, Romuald; Lambert, Jean-Philippe; Tomkova, Marketa; Tischfield, Samuel; Baggiolini, Arianna; Picaud, Sarah; Sarkar, Sovan; Louphrasitthiphol, Pakavarin; Dias, Diogo; Carreira, Suzanne; Humphrey, Timothy C.; Fillipakopoulos, Panagis; White, Richard; Goding, Colin R.. (2024). DNA damage remodels the MITF interactome to increase melanoma genomic instability. GENES & DEVELOPMENT. DOI: 10.1101/gad.350740.123 (http://dx.doi.org/10.1101/gad.350740.123)
Pronovost, Raphael; Rion, Mathis; Tzouras, Nikolaos V.; Nolan, Steven P.; Paquin, Jean-Francois. (2024). Gold-catalyzed hydrofluorination of terminal alkynes using potassium bifluoride (KHF2). CHEMICAL COMMUNICATIONS. DOI: 10.1039/d4cc05049e (http://dx.doi.org/10.1039/d4cc05049e)
Mubaid, Souad; Sanchez, Brenda Janice; Algehani, Rinad A.; Skopenkova, Viktoriia; Adjibade, Pauline; Hall, Derek T.; Busque, Sandrine; Lian, Xian Jin; Ashour, Kholoud; Tremblay, Anne-Marie K.; Carlile, Graeme; Gagne, Jean-Philippe; Diaz-Gaxiola, Andrea; Khattak, Shahryar; Di Marco, Sergio; Thomas, David Y.; Poirier, Guy G.; Gallouzi, Imed-Eddine. (2024). Tankyrase-1 regulates RBP-mediated mRNA turnover to promote muscle fiber formation. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkae059 (http://dx.doi.org/10.1093/nar/gkae059)
Despres, Philippe C.; Dube, Alexandre K.; Picard, Marie-Eve; Grenier, Jordan; Shi, Rong; Landry, Christian R.. (2024). Compensatory mutations potentiate constructive neutral evolution by gene duplication. SCIENCE. DOI: 10.1126/science.ado5719 (http://dx.doi.org/10.1126/science.ado5719)
Tong, Xiao-Yang; Zhang, Yi; Pang, Jin-Xin; Liu, Bao-Lin; Biron, Eric; Rahman, Md R. T.; Qiao, Yong-Jin; Bing, Qi-Jie; Gao, Xu-Ying. (2024). Application of the Effect of Nonthermal Technologies on the Oxidation of Proteins and Lipids in Pigeon Meat during Chilled Storage. JOURNAL OF FOOD BIOCHEMISTRY. DOI: 10.1155/2024/6696954 (http://dx.doi.org/10.1155/2024/6696954)
Cashman-Kadri, Samuel; Lague, Patrick; Subirade, Muriel; Fliss, Ismail; Beaulieu, Lucie. (2024). Insights into Molecular Interactions between a GAPDH-Related Fish Antimicrobial Peptide, Analogs Thereof, and Bacterial Membranes. BIOCHEMISTRY. DOI: 10.1021/acs.biochem.4c00049 (http://dx.doi.org/10.1021/acs.biochem.4c00049)
Teyssier, Valentine; Williamson, Casey R.; Shata, Erka; Rosen, Stephanie P.; Jones, Nina; Bisson, Nicolas. (2024). Adapting to change: resolving the dynamic and dual roles of NCK1 and NCK2. BIOCHEMICAL JOURNAL. DOI: 10.1042/BCJ20230232 (http://dx.doi.org/10.1042/BCJ20230232)
Gunathilake, K. M. Damitha; Makumi, Angela; Loignon, Stephanie; Tremblay, Denise; Labrie, Simon; Svitek, Nicholas; Moineau, Sylvain. (2024). Diversity of Salmonella enterica phages isolated from chicken farms in Kenya. MICROBIOLOGY SPECTRUM. DOI: 10.1128/spectrum.02729-23 (http://dx.doi.org/10.1128/spectrum.02729-23)
Iqbal, Jamshed; Bano, Sehrish; Khan, Imtiaz Ali; Sevigny, Jean; Huang, Qing. (2024). Ectonucleotidase inhibitors: an updated patent review (2017-2023). EXPERT OPINION ON THERAPEUTIC PATENTS. DOI: 10.1080/13543776.2024.2423023 (http://dx.doi.org/10.1080/13543776.2024.2423023)
Paquin, Pascal; DeGrace, Nicolas; Belanger-Chabot, Guillaume; Paquin, Jean-Francois. (2024). Synthesis of Substituted Pentafluorosulfanylpyrazoles Under Flow Conditions. JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1021/acs.joc.3c02295 (http://dx.doi.org/10.1021/acs.joc.3c02295)
Bedard, Camille; Gagnon-Arsenault, Isabelle; Boisvert, Jonathan; Plante, Samuel; Dube, Alexandre K.; Pageau, Alicia; Fijarczyk, Anna; Sharma, Jehoshua; Maroc, Laetitia; Shapiro, Rebecca S.; Landry, Christian R.. (2024). Most azole resistance mutations in the Candida albicans drug target confer cross-resistance without intrinsic fitness cost. NATURE MICROBIOLOGY. DOI: 10.1038/s41564-024-01819-2 (http://dx.doi.org/10.1038/s41564-024-01819-2)
Auger, Maud; Sorroza-Martinez, Luis; Brahiti, Nadine; Huppe, Carole-Ann; Faucher-Giguere, Laurence; Arbi, Imen; Hervault, Maxime; Cheng, Xue; Gaillet, Bruno; Couture, Frederic; Guay, David; Soultan, Al-Halifa. (2024). Enhancing peptide and PMO delivery to mouse airway epithelia by chemical conjugation with the amphiphilic peptide S10. MOLECULAR THERAPY NUCLEIC ACIDS. DOI: 10.1016/j.omtn.2024.102290 (http://dx.doi.org/10.1016/j.omtn.2024.102290)
Bautista, Carla; Gagnon-Arsenault, Isabelle; Utrobina, Mariia; Fijarczyk, Anna; Bendixsen, Devin P.; Stelkens, Rike; Landry, Christian R.. (2024). Hybrid adaptation is hampered by Haldane's sieve. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-024-54105-4 (http://dx.doi.org/10.1038/s41467-024-54105-4)
Bayat, Fereshteh; Hilal, Arwa; Thirugnanasampanthar, Mathura; Tremblay, Denise; Filipe, Carlos D. M.; Moineau, Sylvain; Didar, Tohid F.; Hosseinidoust, Zeinab. (2024). High throughput platform technology for rapid target identification in personalized phage therapy. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-024-49710-2 (http://dx.doi.org/10.1038/s41467-024-49710-2)
Oechslin, Frank; Zhu, Xiaojun; Morency, Carlee; Somerville, Vincent; Shi, Rong; Moineau, Sylvain. (2024). Fermentation Practices Select for Thermostable Endolysins in Phages. MOLECULAR BIOLOGY AND EVOLUTION. DOI: 10.1093/molbev/msae055 (http://dx.doi.org/10.1093/molbev/msae055)
Resch, Gregory; Brives, Charlotte; Debarbieux, Laurent; Hodges, Francesca E.; Kirchhelle, Claas; Laurent, Frederic; Moineau, Sylvain; Martins, Ana Filipa Moreira; Rohde, Christine. (2024). Between Centralization and Fragmentation: The Past, Present, and Future of Phage Collections. PHAGE-THERAPY APPLICATIONS AND RESEARCH. DOI: 10.1089/phage.2023.0043 (http://dx.doi.org/10.1089/phage.2023.0043)
Zhang, Yi; Xie, Guojia; Lee, Ji-Eun; Zandian, Mohamad; Sudarshan, Deepthi; Estavoyer, Benjamin; Benz, Caroline; Viita, Tiina; Asgaritarghi, Golareh; Lachance, Catherine; Messmer, Clemence; Simonetti, Leandro; Sinha, Vikrant Kumar; Lambert, Jean-Philippe; Chen, Yu-Wen; Wang, Shu-Ping; Ivarsson, Ylva; Affar, El Bachir; Cote, Jacques; Ge, Kai; Kutateladze, Tatiana G.. (2024). ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-024-49391-x (http://dx.doi.org/10.1038/s41467-024-49391-x)
Khodaparastasgarabad, Nastaran; Couture, Manon; Greener, Jesse. (2024). Dynamic Metabolic Bottlenecks of a Geobacter Sulfurreducens Bioelectrochemical System Studied Using Microfluidics and the Arrhenius Equation. CHEMCATCHEM. DOI: 10.1002/cctc.202401102 (http://dx.doi.org/10.1002/cctc.202401102)
Leclerc, Christina; St-Gelais, Jacob; Cecioni, Samy; Giguere, Denis. (2024). Synthesis and hydrolysis of aryl fluoroglycosides. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2023.110232 (http://dx.doi.org/10.1016/j.jfluchem.2023.110232)
Addablah, Audrey A.; Ngazoa-Kakou, Solange E.; Adioumani, Emmanuella A.; Labrie, Simon J.; Tremblay, Denise M.; Gunathilake, Damitha; Moineau, Sylvain. (2024). Complete genome of Escherichia phages Carena and JoYop. MICROBIOLOGY RESOURCE ANNOUNCEMENTS. DOI: 10.1128/mra.01233-23 (http://dx.doi.org/10.1128/mra.01233-23)
Morneau, Zacharie; Moineau, Sylvain. (2024). The double play of a phage HTH regulator. TRENDS IN MICROBIOLOGY. DOI: 10.1016/j.tim.2024.09.005 (http://dx.doi.org/10.1016/j.tim.2024.09.005)
Koirala, Manoj; Merindol, Natacha; Karimzadegan, Vahid; Gelinas, Sarah-Eve; Liyanage, Nuwan Sameera; Lamichhane, Basanta; Tobon, Maria Camila Garcia; Lague, Patrick; Desgagne-Penix, Isabel. (2024). Kinetic and in silico structural characterization of norbelladine O-methyltransferase of Amaryllidaceae alkaloids biosynthesis. JOURNAL OF BIOLOGICAL CHEMISTRY. DOI: 10.1016/j.jbc.2024.107649 (http://dx.doi.org/10.1016/j.jbc.2024.107649)
Bertrand, Xavier; Aissaoui, Doria; Col, Oceane Meryem; Pucheault, Mathieu; Chabaud, Laurent; Paquin, Jean-Francois. (2024). Improved conditions for the synthesis of tertiary fluorides using a KF/ H2SO4 combination. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2024.110338 (http://dx.doi.org/10.1016/j.jfluchem.2024.110338)
Rodriguez, Cristina Leal; Shah, Shiraz A.; Rasmussen, Morten Arendt; Thorsen, Jonathan; Boulund, Ulrika; Pedersen, Casper-Emil Tingskov; Castro-Mejia, Josue L.; Poulsen, Christina Egeo; Poulsen, Casper Sahl; Deng, Ling; Larsen, Frej Andreas Nohr; Widdowson, Michael; Zhang, Yichang; Sorensen, Soren J.; Moineau, Sylvain; Petit, Marie-Agnes; Chawes, Bo; Bonnelykke, Klaus; Nielsen, Dennis S.; Stokholm, Jakob. (2024). The infant gut virome is associated with preschool asthma risk independently of bacteria. NATURE MEDICINE. DOI: 10.1038/s41591-023-02685-x (http://dx.doi.org/10.1038/s41591-023-02685-x)
Fraser, Tommy; Harbour, Zakiel; Voyer, Normand; Cardinal, Sebastien. (2024). Chemo- and Regioselective Demethylation of 2-Bromo-α-resorcylic Acid Derivatives Using Alkylthiolate Salts. SYNLETT. DOI: 10.1055/a-2370-7112 (http://dx.doi.org/10.1055/a-2370-7112)
Yang, Zhenlin; Mameri, Amel; Cattoglio, Claudia; Lachance, Catherine; Florez Ariza, Alfredo Jose; Luo, Jie; Humbert, Jonathan; Sudarshan, Deepthi; Banerjea, Arul; Galloy, Maxime; Fradet-Turcotte, Amelie; Lambert, Jean-Philippe; Ranish, Jeff A.; Cote, Jacques; Nogales, Eva. (2024). Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex. SCIENCE. DOI: 10.1126/science.adl5816 (http://dx.doi.org/10.1126/science.adl5816)
Lachance, Gabriel Philippe; Gauvreau, Dominic; Boisselier, Elodie; Boukadoum, Mounir; Miled, Amine. (2024). Breaking Barriers: Exploring Neurotransmitters through In Vivo vs. In Vitro Rivalry. SENSORS. DOI: 10.3390/s24020647 (http://dx.doi.org/10.3390/s24020647)
Khodaparastasgarabad, Nastaran; Couture, Manon; Greener, Jesse. (2024). A microfluidic study of acetate conversion kinetics in a microbial electrolysis cell: The role of age, concentration and flow on biofilm permeability. SENSORS AND ACTUATORS B-CHEMICAL. DOI: 10.1016/j.snb.2024.135779 (http://dx.doi.org/10.1016/j.snb.2024.135779)
Yustis, Juan-Carlos; Devoucoux, Maeva; Cote, Jacques. (2024). The Functional Relationship Between RNA Splicing and the Chromatin Landscape. JOURNAL OF MOLECULAR BIOLOGY. DOI: 10.1016/j.jmb.2024.168614 (http://dx.doi.org/10.1016/j.jmb.2024.168614)
Cisneros, Angel F.; Nielly-Thibault, Lou; Mallik, Saurav; Levy, Emmanuel D.; Landry, Christian R.. (2024). Mutational biases favor complexity increases in protein interaction networks after gene duplication. MOLECULAR SYSTEMS BIOLOGY. DOI: 10.1038/s44320-024-00030-z (http://dx.doi.org/10.1038/s44320-024-00030-z)
Kulhankova, Katarina; Cheng, Anna X.; Traore, Soumba; Auger, Maud; Pelletier, Mia; Hervault, Maxime; Wells, Kevin D.; Green, Jonathan A.; Byrne, Addison; Nelson, Benjamin; Sponchiado, Mariana; Boosani, Chandra; Heffner, Caleb S.; Snow, Kathy J.; Murray, Stephen A.; Villacreses, Raul A.; Rector, Michael, V; Gansemer, Nicholas D.; Stoltz, David A.; Allamargot, Chantal; Couture, Frederic; Hemez, Colin; Hallee, Stephanie; Barbeau, Xavier; Harvey, Mario; Lauvaux, Coraline; Gaillet, Bruno; Newby, Gregory A.; Liu, David R.; McCray Jr, Paul B.; Guay, David. (2024). Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkae819 (http://dx.doi.org/10.1093/nar/gkae819)
de Melo, Alessandra G.; Morency, Carlee; Moineau, Sylvain. (2024). Virulence-associated factors as targets for phage infection. CURRENT OPINION IN MICROBIOLOGY. DOI: 10.1016/j.mib.2024.102471 (http://dx.doi.org/10.1016/j.mib.2024.102471)
Aube, Simon; Landry, Christian R.. (2024). How genotype-by-environment interactions on fitness emerge. NATURE ECOLOGY & EVOLUTION. DOI: 10.1038/s41559-024-02577-4 (http://dx.doi.org/10.1038/s41559-024-02577-4)
Mellouk, Abdelkader; Jaouen, Paul; Ruel, Louis-Jacques; Le, Michel; Martini, Cyrielle; Moraes, Trevor F.; El Bakkouri, Majida; Lague, Patrick; Boisselier, Elodie; Calmettes, Charles. (2024). POTRA domains of the TamA insertase interact with the outer membrane and modulate membrane properties. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. DOI: 10.1073/pnas.2402543121 (http://dx.doi.org/10.1073/pnas.2402543121)
Landry, Christian R.. (2024). Cellular evolution in the population genetics environment. TRENDS IN ECOLOGY & EVOLUTION. DOI: 10.1016/j.tree.2024.04.009 (http://dx.doi.org/10.1016/j.tree.2024.04.009)
Bradley, David; Hogrebe, Alexander; Dandage, Rohan; Dube, Alexandre K.; Leutert, Mario; Dionne, Ugo; Chang, Alexis; Villen, Judit; Landry, Christian R.. (2024). The fitness cost of spurious phosphorylation. EMBO JOURNAL. DOI: 10.1038/s44318-024-00200-7 (http://dx.doi.org/10.1038/s44318-024-00200-7)
2023
Gauthier, Raphael; Paquin, Jean-Francois. (2023). Hydrofluorination of Alkynes: From (E) to (Z). CHEMISTRY-A EUROPEAN JOURNAL. DOI: 10.1002/chem.202301896 (http://dx.doi.org/10.1002/chem.202301896)
Bertrand, Xavier; Pucheault, Mathieu; Chabaud, Laurent; Paquin, Jean-Francois. (2023). Synthesis of Tertiary Fluorides through an Acid-Mediated Deoxyfluorination of Tertiary Alcohols. JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1021/acs.joc.3c01558 (http://dx.doi.org/10.1021/acs.joc.3c01558)
Kienzle, Laura; Bettinazzi, Stefano; Choquette, Thierry; Brunet, Marie; Khorami, Hajar Hosseini; Jacques, Jean-Francois; Moreau, Mathilde; Roucou, Xavier; Landry, Christian R.; Angers, Annie; Breton, Sophie. (2023). A small protein coded within the mitochondrial canonical gene nd4 regulates mitochondrial bioenergetics. BMC BIOLOGY. DOI: 10.1186/s12915-023-01609-y (http://dx.doi.org/10.1186/s12915-023-01609-y)
Beneyton, Adele; Nonfoux, Louis; Gagne, Jean-Philippe; Rodrigue, Amelie; Kothari, Charu; Atalay, Nurgul; Hendzel, Michael J.; Poirier, Guy G.; Masson, Jean-Yves. (2023). The dynamic process of covalent and non-covalent PARylation in the maintenance of genome integrity: a focus on PARP inhibitors. NAR CANCER. DOI: 10.1093/narcan/zcad043 (http://dx.doi.org/10.1093/narcan/zcad043)
da Silva, Alisson Coldebella; Scholl, Juliete Nathali; de Fraga Dias, Amanda; Weber, Augusto Ferreira; Morrone, Fernanda Bueno; Cruz-Lopez, Olga; Conejo-Garcia, Ana; Campos, Joaquin Maria; Sevigny, Jean; Figueiro, Fabricio; Battastini, Ana Maria Oliveira. (2023). Preclinical evaluation of bozepinib in bladder cancer cell lines: modulation of the NPP1 enzyme. PURINERGIC SIGNALLING. DOI: 10.1007/s11302-023-09975-6 (http://dx.doi.org/10.1007/s11302-023-09975-6)
Tremblay, Thomas; Haguette, Penelope; Robert-Scott, Gabrielle; Alcee, Jessica B.; Berube, Christopher; Bergeron, Catherine; Voyer, Normand; Giguere, Denis. (2023). Synthesis of Lincosamide Analogues via Oxime Resin Aminolysis. SYNLETT. DOI: 10.1055/a-1948-7153 (http://dx.doi.org/10.1055/a-1948-7153)
Evans-Yamamoto, Daniel; Dube, Alexandre K.; Saha, Gourav; Plante, Samuel; Bradley, David; Gagnon-Arsenault, Isabelle; Landry, Christian R.. (2023). Parallel Nonfunctionalization of CK1δ/ε Kinase Ohnologs Following a Whole-Genome Duplication Event. MOLECULAR BIOLOGY AND EVOLUTION. DOI: 10.1093/molbev/msad246 (http://dx.doi.org/10.1093/molbev/msad246)
Berube, Christopher; Guay, Louis-David; Fraser, Tommy; Lapointe, Victor; Cardinal, Sebastien; Biron, Eric. (2023). Convenient route to Fmoc-homotyrosine via metallaphotoredox catalysis and its use in the total synthesis of anabaenopeptin cyclic peptides. ORGANIC & BIOMOLECULAR CHEMISTRY. DOI: 10.1039/d3ob01608k (http://dx.doi.org/10.1039/d3ob01608k)
Jadoon, Muhammad Siraj Khan; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2023). Synthesis of new class of indole acetic acid sulfonate derivatives as ectonucleotidases inhibitors. RSC ADVANCES. DOI: 10.1039/d3ra04266a (http://dx.doi.org/10.1039/d3ra04266a)
Cisneros, Angel F.; Gagnon-Arsenault, Isabelle; Dube, Alexandre K.; Despres, Philippe C.; Kumar, Pradum; Lafontaine, Kiana; Pelletier, Joelle N.; Landry, Christian R.. (2023). Epistasis between promoter activity and coding mutations shapes gene evolvability. SCIENCE ADVANCES. DOI: 10.1126/sciadv.add9109 (http://dx.doi.org/10.1126/sciadv.add9109)
Cardoso, Andreia Machado; Aneli, Nyasmin Mendes; Lammers, Monica; Manica, Aline; Zanini, Daniela; Maciel, Sarah Franco Vieira de Oliveira; Sevigny, Jean; Corralo, Vanessa da Silva; De Sa, Clodoaldo Antonio. (2023). Resistance training reduces platelet activation in hypertensive women: the role of purinergic signaling. JOURNAL OF HYPERTENSION. DOI: 10.1097/HJH.0000000000003529 (http://dx.doi.org/10.1097/HJH.0000000000003529)
El Zawily, Amr; Vizeacoumar, Frederick S.; Dahiya, Renuka; Banerjee, Sara L.; Bhanumathy, Kalpana K.; Elhasasna, Hussain; Hanover, Glinton; Sharpe, Jessica C.; Sanchez, Malkon G.; Greidanus, Paul; Stacey, R. Greg; Moon, Kyung-Mee; Alexandrov, Ilya; Himanen, Juha P.; Nikolov, Dimitar B.; Fonge, Humphrey; White, Aaron P.; Foster, Leonard J.; Wang, Bingcheng; Toosi, Behzad M.; Bisson, Nicolas; Mirzabekov, Tajib A.; Vizeacoumar, Franco J.; Freywald, Andrew. (2023). A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy. CLINICAL CANCER RESEARCH. DOI: 10.1158/1078-0432.CCR-22-2535 (http://dx.doi.org/10.1158/1078-0432.CCR-22-2535)
Bricha, Salma; Cote-Cyr, Melanie; Tremblay, Thomas; Nguyen, Phuong Trang; St-Louis, Philippe; Giguere, Denis; Archambault, Denis; Bourgault, Steve. (2023). Synthetic Multicomponent Nanovaccines Based on the Molecular Co-assembly of β-Peptides Protect against Influenza A Virus. ACS INFECTIOUS DISEASES. DOI: 10.1021/acsinfecdis.2c00610 (http://dx.doi.org/10.1021/acsinfecdis.2c00610)
Zaman, Gohar; Ullah, Saif; Uzair, Muhammad; Batool, Sania; Ahmad, Haseen; Ullah, Farman; Pelletier, Julia; Sevigny, Jean; Iqbal, Jamshed; Hassan, Abbas. (2023). Synthesis of Thieno[3,2-d]pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h-NTPDase Inhibitors. CHEMMEDCHEM. DOI: 10.1002/cmdc.202300165 (http://dx.doi.org/10.1002/cmdc.202300165)
Shahin, Afnan, I; Zaraei, Seyed-Omar; AlKubaisi, Bilal O.; Ullah, Saif; Anbar, Hanan S.; El-Gamal, Randa; Menon, Varsha; Abdel-Maksoud, Mohammed S.; Oh, Chang-Hyun; El-Awady, Raafat; Gelsleichter, Nicolly Espindola; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed; Al-Tel, Taleb H.; El-Gamal, Mohammed, I. (2023). Design and synthesis of new adamantyl derivatives as promising antiproliferative agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. DOI: 10.1016/j.ejmech.2022.114958 (http://dx.doi.org/10.1016/j.ejmech.2022.114958)
Tremblay, Thomas; Bergeron, Catherine; Gagnon, Dominic; Berube, Christopher; Voyer, Normand; Richard, Dave; Giguere, Denis. (2023). Squaramide Tethered Clindamycin, Chloroquine, and Mortiamide Hybrids: Design, Synthesi s , and Antimalarial Activity. ACS MEDICINAL CHEMISTRY LETTERS. DOI: 10.1021/acsmedchemlett.2c00531 (http://dx.doi.org/10.1021/acsmedchemlett.2c00531)
Berger, Marie-Rose Ouellet-Du; Boucher, Maxim; Paquin, Jean-Francois. (2023). Light-activation of SF5Cl for the atom transfer radical addition onto alkenes and alkynes. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2023.110131 (http://dx.doi.org/10.1016/j.jfluchem.2023.110131)
Mastalerz, Vincent; Lam, Kevin; Paquin, Jean-Francois. (2023). Exploration toward the synthesis of aliphatic SF5-containing compounds using the Kolbe reaction. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2023.110113 (http://dx.doi.org/10.1016/j.jfluchem.2023.110113)
Louphrasitthiphol, Pakavarin; Loffreda, Alessia; Pogenberg, Vivian; Picaud, Sarah; Schepsky, Alexander; Friedrichsen, Hans; Zeng, Zhiqiang; Lashgari, Anahita; Thomas, Benjamin; Patton, E. Elizabeth; Wilmanns, Matthias; Filippakopoulos, Panagis; Lambert, Jean-Philippe; Steingrimsson, Eirikur; Mazza, Davide; Goding, Colin R.. (2023). Acetylation reprograms MITF target selectivity and residence time. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-023-41793-7 (http://dx.doi.org/10.1038/s41467-023-41793-7)
Pimont-Farge, Mathilde; Perreault, Veronique; Brisson, Guillaume; Otis, Francois; Voyer, Normand; Suwal, Shyam; Pouliot, Yves; Doyen, Alain. (2023). Hydrogel formation from peptides of a B-lactoglobulin tryptic hydrolysate: Contribution of self-assembling peptide B-Lg f1-8. FOOD HYDROCOLLOIDS. DOI: 10.1016/j.foodhyd.2023.108765 (http://dx.doi.org/10.1016/j.foodhyd.2023.108765)
Seguin, Jean-Christophe; Gagnon, Dominic; Belanger, Sarah; Richard, Dave; Fernandez, Xavier; Boudreau, Stephane; Voyer, Normand. (2023). Chemical Composition and Antiplasmodial Activity of the Essential Oil of Rhododendron subarcticum Leaves from Nunavik, Quebec, Canada. ACS OMEGA. DOI: 10.1021/acsomega.3c00235 (http://dx.doi.org/10.1021/acsomega.3c00235)
Franca, Tanos C. C.; Goncalves, Arlan da Silva; Berube, Christopher; Voyer, Normand; Aubry, Norman; LaPlante, Steven R.. (2023). Determining the Predominant Conformations of Mortiamides A-D in Solution Using NMR Data and Molecular Modeling Tools. ACS OMEGA. DOI: 10.1021/acsomega.3c01206 (http://dx.doi.org/10.1021/acsomega.3c01206)
Gauthier, Raphael; Tzouras, Nikolaos V.; Nolan, Steven P.; Paquin, Jean-Francois. (2023). Exploiting the inductive effect of the trifluoromethyl group: regioselective gold-catalyzed hydration of 2,2,2-trifluoroethyl-substituted alkynes. CHEMICAL COMMUNICATIONS. DOI: 10.1039/d3cc02034g (http://dx.doi.org/10.1039/d3cc02034g)
Viita, Tiina; Cote, Jacques. (2023). The MOZ-BRPF1 acetyltransferase complex in epigenetic crosstalk linked to gene regulation, development, and human diseases. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. DOI: 10.3389/fcell.2022.1115903 (http://dx.doi.org/10.3389/fcell.2022.1115903)
Mameri, Amel; Cote, Jacques. (2023). JAZF1: A metabolic actor subunit of the NuA4/TIP60 chromatin modifying complex. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. DOI: 10.3389/fcell.2023.1134268 (http://dx.doi.org/10.3389/fcell.2023.1134268)
Gonthier, Kevin; Weidmann, Cindy; Berthiaume, Line; Jobin, Cynthia; Lacouture, Aurelie; Lafront, Camille; Harvey, Mario; Neveu, Bertrand; Loehr, Jeremy; Bergeron, Alain; Fradet, Yves; Lacombe, Louis; Riopel, Julie; Latulippe, Eva; Atallah, Chantal; Shum, Michael; Lambert, Jean-Philippe; Pouliot, Frederic; Pelletier, Martin; Audet-Walsh, Etienne. (2023). Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic-mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer. MOLECULAR ONCOLOGY. DOI: 10.1002/1878-0261.13441 (http://dx.doi.org/10.1002/1878-0261.13441)
Huang, Xiaofeng; Gu, Wei; Zhang, Jiaoyue; Lan, Ying; Colarusso, Jonathan L.; Li, Sanlan; Pertl, Christoph; Lu, Jiaqi; Kim, Hyunkee; Zhu, Jian; Breault, David T.; Sevigny, Jean; Zhou, Qiao. (2023). Stomach-derived human insulin-secreting organoids restore glucose homeostasis. NATURE CELL BIOLOGY. DOI: 10.1038/s41556-023-01130-y (http://dx.doi.org/10.1038/s41556-023-01130-y)
Sahraei, Abolfazl Alizadeh; Bohorquez, Barbara Mejia; Tremblay, Denise; Moineau, Sylvain; Garnier, Alain; Larachi, Faical; Lague, Patrick. (2023). Insight into the Binding Mechanisms of Quartz-Selective Peptides: Toward Greener Flotation Processes. ACS APPLIED MATERIALS & INTERFACES. DOI: 10.1021/acsami.3c01275 (http://dx.doi.org/10.1021/acsami.3c01275)
Naasani, Liliana I. Sous; Sevigny, Jean; Moulin, Veronique J.; Wink, Marcia Rosangela. (2023). UTP increases wound healing in the self assembled skin substitute (SASS). JOURNAL OF CELL COMMUNICATION AND SIGNALING. DOI: 10.1007/s12079-023-00725-2 (http://dx.doi.org/10.1007/s12079-023-00725-2)
Ledoux, Nassim; Lelong, Emeline I. J.; Simard, Alexandre; Hussein, Samer; Adjibade, Pauline; Lambert, Jean-Philippe; Mazroui, Rachid. (2023). The Identification of Nuclear FMRP Isoform Iso6 Partners. CELLS. DOI: 10.3390/cells12242807 (http://dx.doi.org/10.3390/cells12242807)
Zaigham, Zahid Hussain; Ullah, Saif; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed; Hassan, Abbas. (2023). Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h-NTPDases. RSC ADVANCES. DOI: 10.1039/d3ra03874b (http://dx.doi.org/10.1039/d3ra03874b)
Nielsen, Tue Kjaergaard; Forero-Junco, Laura Milena; Kot, Witold; Moineau, Sylvain; Hansen, Lars Hestbjerg; Riber, Leise. (2023). Detection of nucleotide modifications in bacteria and bacteriophages: Strengths and limitations of current technologies and software. MOLECULAR ECOLOGY. DOI: 10.1111/mec.16679 (http://dx.doi.org/10.1111/mec.16679)
Hanover, Glinton; Vizeacoumar, Frederick S.; Banerjee, Sara L.; Nair, Raveena; Dahiya, Renuka; Osornio-Hernandez, Ana I.; Morales, Alain Morejon; Freywald, Tanya; Himanen, Juha P.; Toosi, Behzad M.; Bisson, Nicolas; Vizeacoumar, Franco J.; Freywald, Andrew. (2023). Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR. CELL REPORTS. DOI: 10.1016/j.celrep.2023.112670 (http://dx.doi.org/10.1016/j.celrep.2023.112670)
Ferlet, Remy; Pucheault, Mathieu; Chabaud, Laurent; Paquin, Jean-Francois. (2023). Metal-Free Defluoroborylation of 3,3-Difluoropropenes. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. DOI: 10.1002/ejoc.202300731 (http://dx.doi.org/10.1002/ejoc.202300731)
Noronha-Matos, Jose Bernardo; Pinto-Cardoso, Rui; Bessa-Andres, Catarina; Magalhaes-Cardoso, Maria Teresa; Ferreirinha, Fatima; Costa, Maria Adelina; Marinhas, Jose; Freitas, Rolando; Lemos, Rui; Vilaca, Adelio; Oliveira, Antonio; Pelletier, Julie; Sevigny, Jean; Correia-de-Sa, Paulo. (2023). Silencing NTPDase3 activity rehabilitates the osteogenic commitment of post-menopausal stem cell bone progenitors. STEM CELL RESEARCH & THERAPY. DOI: 10.1186/s13287-023-03315-6 (http://dx.doi.org/10.1186/s13287-023-03315-6)
Boccacci, Yelena; Dumont, Nellie; Doyon, Yannick; Laganiere, Josee. (2023). Accessory-cell-free differentiation of hematopoietic stem and progenitor cells into mature red blood cells. CYTOTHERAPY. DOI: 10.1016/j.jcyt.2023.07.007 (http://dx.doi.org/10.1016/j.jcyt.2023.07.007)
da Silva, Walmir; Ribeiro, Isadora Cunha; Agripino, Joice de Melo; Ferraz da Silva, Victor Hugo; de Souza, Luciana Angelo; Oliveira, Tatiana Aparecida; Bressan, Gustavo Costa; Vasconcellos, Raphael de Souza; Dumas, Carole; Pelletier, Julie; Sevigny, Jean; Papadopoulou, Barbara; Rangel Fietto, Juliana Lopes. (2023). Leishmania infantum NTPDase1 and NTPDase2 play an important role in infection and nitric oxide production in macrophages. ACTA TROPICA. DOI: 10.1016/j.actatropica.2022.106732 (http://dx.doi.org/10.1016/j.actatropica.2022.106732)
Jolicoeur, Alice P.; Lemay, Marie-Laurence; Beaubien, Elyse; Belanger, Jessy; Bergeron, Claudia; Bourque-Leblanc, Francoise; Dore, Laurie; Dupuis, Marie-Eve; Fleury, Audrey; Garneau, Josiane E.; Labrie, Simon J.; Labrie, Steve; Lacasse, Genevieve; Lamontagne-Drolet, Marianne; Lessard-Hurtubise, Roxanne; Martel, Bruno; Menasria, Rym; Morin-Pelchat, Rachel; Pageau, Gabrielle; Samson, Julie E.; Rousseau, Genevieve M.; Tremblay, Denise M.; Duquenne, Manon; Lamoureux, Maryse; Moineau, Sylvain. (2023). Longitudinal Study of Lactococcus Phages in a Canadian Cheese Factory. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. DOI: 10.1128/aem.00421-23 (http://dx.doi.org/10.1128/aem.00421-23)
Biot-Pelletier, Damien; Bettinazzi, Stefano; Gagnon-Arsenault, Isabelle; Dube, Alexandre K.; Bedard, Camille; Nguyen, Tuc H. M.; Fiumera, Heather L.; Breton, Sophie; Landry, Christian R.. (2023). Evolutionary Trajectories are Contingent on Mitonuclear Interactions. MOLECULAR BIOLOGY AND EVOLUTION. DOI: 10.1093/molbev/msad061 (http://dx.doi.org/10.1093/molbev/msad061)
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Sous Naasani, Liliana Ivet; Azevedo, Jessica Goncalves; Sevigny, Jean; de Oliveira, Tiago Franco; Maria-Engler, Silvya Stuchi; Wink, Marcia Rosangela. (2023). A study on solar radiation prediction using medium-range weather forecasts. BIOCHEMISTRY AND CELL BIOLOGY. DOI: 10.1139/bcb-2022-0058 (http://dx.doi.org/10.1139/bcb-2022-0058)
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Lemieux, Pascale; Bradley, David; Dube, Alexandre K.; Dionne, Ugo; Landry, Christian R.. (2023). Dissection of the role of a Src homology 3 domain in the evolution of binding preference of paralogous proteins. GENETICS. DOI: 10.1093/genetics/iyad175 (http://dx.doi.org/10.1093/genetics/iyad175)
Aube, Simon; Nielly-Thibault, Lou; Landry, Christian R.. (2023). Evolutionary trade-off and mutational bias could favor transcriptional over translational divergence within paralog pairs. PLOS GENETICS. DOI: 10.1371/journal.pgen.1010756 (http://dx.doi.org/10.1371/journal.pgen.1010756)
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Gashti, Anahita Bakhshizadeh; Chahal, Parminder S.; Gaillet, Bruno; Garnier, Alain. (2023). Purification of recombinant vesicular stomatitis virus-based HIV vaccine candidate. VACCINE. DOI: 10.1016/j.vaccine.2023.02.058 (http://dx.doi.org/10.1016/j.vaccine.2023.02.058)
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Hosseini, Nava; Paquet, Valerie E.; Marcoux, Pierre-Etienne; Alain, Charles-Antoine; Paquet, Maude F.; Moineau, Sylvain; Charette, Steve J.. (2023). MQM1, a bacteriophage infecting strains of Aeromonas salmonicida subspecies salmonicida carrying Prophage 3. VIRUS RESEARCH. DOI: 10.1016/j.virusres.2023.199165 (http://dx.doi.org/10.1016/j.virusres.2023.199165)
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Philippe, Cecile; Cornuault, Jeffrey K.; de Melo, Alessandra G.; Morin-Pelchat, Rachel; Jolicoeur, Alice P.; Moineau, Sylvain. (2023). The never-ending battle between lactic acid bacteria and their phages. FEMS MICROBIOLOGY REVIEWS. DOI: 10.1093/femsre/fuad035 (http://dx.doi.org/10.1093/femsre/fuad035)
Campbell, Zoe A.; Njiru, Nelly; Mhone, Amos Lucky; Makumi, Angela; Moineau, Sylvain; Svitek, Nicholas. (2023). Gender-Responsive Design of Bacteriophage Products to Enhance Adoption by Chicken Keepers in Kenya. VIRUSES-BASEL. DOI: 10.3390/v15030746 (http://dx.doi.org/10.3390/v15030746)
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Dash, Shantoshini; Farnos, Omar; Yang, Zeyu; Perumal, Ayyappasamy Sudalaiyadum; Fulber, Julia Puppin Chaves; Venereo-Sanchez, Alina; Leclerc, Denis; Kamen, Amine A.. (2023). A rapid procedure to generate stably transfected HEK293 suspension cells for recombinant protein manufacturing: Yield improvements, bioreactor production and downstream processing. PROTEIN EXPRESSION AND PURIFICATION. DOI: 10.1016/j.pep.2023.106295 (http://dx.doi.org/10.1016/j.pep.2023.106295)
Shah, Shiraz A.; Deng, Ling; Thorsen, Jonathan; Pedersen, Anders G.; Dion, Moira B.; Castro-Mejia, Josue L.; Silins, Ronalds; Romme, Fie O.; Sausset, Romain; Jessen, Leon E.; Ndela, Eric Olo; Hjelmso, Mathis; Rasmussen, Morten A.; Redgwell, Tamsin A.; Rodriguez, Cristina Leal; Vestergaard, Gisle; Zhang, Yichang; Chawes, Bo; Bonnelykke, Klaus; Sorensen, Soren J.; Bisgaard, Hans; Enault, Francois; Stokholm, Jakob; Moineau, Sylvain; Petit, Marie-Agnes; Nielsen, Dennis S.. (2023). Expanding known viral diversity in the healthy infant gut. NATURE MICROBIOLOGY. DOI: 10.1038/s41564-023-01345-7 (http://dx.doi.org/10.1038/s41564-023-01345-7)
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de Melo, Alessandra G.; Lemay, Marie-Laurence; Moineau, Sylvain. (2023). The impact of Brevibacterium aurantiacum virulent phages on the production of smear surface-ripened cheeses. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY. DOI: 10.1016/j.ijfoodmicro.2023.110252 (http://dx.doi.org/10.1016/j.ijfoodmicro.2023.110252)
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Loiseau, Alexis; Raiche-Marcoux, Gabrielle; Maranda, Cloe; Bertrand, Nicolas; Boisselier, Elodie. (2023). Animal Models in Eye Research: Focus on Corneal Pathologies. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms242316661 (http://dx.doi.org/10.3390/ijms242316661)
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Hosseini, S. Nazila; Akram, Mohammad Makhdoumi; Das, Partha Sarati; Lazarjan, Vahid Khojasteh; Tremblay, Denise M.; Moineau, Sylvain; Messaddeq, Younes; Gosselin, Benoit. (2023). Multimodal CMOS Biosensor for Microbial Growth Monitoring. IEEE SENSORS JOURNAL. DOI: 10.1109/JSEN.2023.3272620 (http://dx.doi.org/10.1109/JSEN.2023.3272620)
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2022
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2021
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Vincent, Thierry; Gaillet, Bruno; Garnier, Alain. (2021). Optimisation of Cytochrome P450 BM3 Assisted by Consensus-Guided Evolution. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY. DOI: 10.1007/s12010-021-03573-1 (http://dx.doi.org/10.1007/s12010-021-03573-1)
Genois, Marie-Michelle; Gagne, Jean-Philippe; Yasuhara, Takaaki; Jackson, Jessica; Saxena, Sneha; Langelier, Marie-France; Ahel, Ivan; Bedford, Mark T.; Pascal, John M.; Vindigni, Alessandro; Poirier, Guy G.; Zou, Lee. (2021). CARM1 regulates replication fork speed and stress response by stimulating PARP1. MOLECULAR CELL. DOI: 10.1016/j.molcel.2020.12.010 (http://dx.doi.org/10.1016/j.molcel.2020.12.010)
Nabeel-Shah, Syed; Garg, Jyoti; Tchara, Pata-Eting Kougnassoukou; Pearlman, Ronald E.; Lambert, Jean-Philippe; Tetrahymena, Jeffrey. (2021). Functional proteomics protocol for the identification of interaction partners in Tetrahymena thermophila. STAR PROTOCOLS. DOI: 10.1016/j.xpro.2021.100362 (http://dx.doi.org/10.1016/j.xpro.2021.100362)
Marsit, S.; Henault, M.; Charron, G.; Fijarczyk, A.; Landry, C. R.. (2021). The neutral rate of whole-genome duplication varies among yeast species and their hybrids. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-021-23231-8 (http://dx.doi.org/10.1038/s41467-021-23231-8)
Cheng, Xue; Cote, Valerie; Cote, Jacques. (2021). NuA4 and SAGA acetyltransferase complexes cooperate for repair of DNA breaks by homologous recombination. PLOS GENETICS. DOI: 10.1371/journal.pgen.1009459 (http://dx.doi.org/10.1371/journal.pgen.1009459)
Go, Christopher D.; Knight, James D. R.; Rajasekharan, Archita; Rathod, Bhavisha; Hesketh, Geoffrey G.; Abe, Kento T.; Youn, Ji-Young; Samavarchi-Tehrani, Payman; Zhang, Hui; Zhu, Lucie Y.; Popiel, Evelyn; Lambert, Jean-Philippe; Coyaud, Etienne; Cheung, Sally W. T.; Rajendran, Dushyandi; Wong, Cassandra J.; Antonicka, Hana; Pelletier, Laurence; Palazzo, Alexander F.; Shoubridge, Eric A.; Raught, Brian; Gingras, Anne-Claude. (2021). A proximity-dependent biotinylation map of a human cell. NATURE. DOI: 10.1038/s41586-021-03592-2 (http://dx.doi.org/10.1038/s41586-021-03592-2)
Ahmad, Salar; Cote, Valerie; Cote, Jacques. (2021). DNA Damage-Induced Phosphorylation of Histone H2A at Serine 15 Is Linked to DNA End Resection. MOLECULAR AND CELLULAR BIOLOGY. DOI: 10.1128/MCB.00056-21 (http://dx.doi.org/10.1128/MCB.00056-21)
Dandage, Rohan; Landry, Christian R.. (2021). Identifying features of genome evolution to exploit cancer vulnerabilities. CELL SYSTEMS. DOI: 10.1016/j.cels.2021.08.007 (http://dx.doi.org/10.1016/j.cels.2021.08.007)
Philippe, Cecile; Moineau, Sylvain. (2021). The endless battle between phages and CRISPR-Cas systems in Streptococcus thermophilus. BIOCHEMISTRY AND CELL BIOLOGY. DOI: 10.1139/bcb-2020-0593 (http://dx.doi.org/10.1139/bcb-2020-0593)
Zarrouk, Karima; Zhu, Xiaojun; Pham, Van Dung; Goyette, Nathalie; Piret, Jocelyne; Shi, Rong; Boivin, Guy. (2021). Impact of Amino Acid Substitutions in Region II and Helix K of Herpes Simplex Virus 1 and Human Cytomegalovirus DNA Polymerases on Resistance to Foscarnet. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. DOI: 10.1128/AAC.00390-21 (http://dx.doi.org/10.1128/AAC.00390-21)
Ahmad, Salar; Cote, Valerie; Chengid, Xue; Bourriquen, Gaelle; Sapountzi, Vasileia; Altafid, Mohammed; Cote, Jacques. (2021). Antagonistic relationship of NuA4 with the non-homologous end-joining machinery at DNA damage sites. PLOS GENETICS. DOI: 10.1371/journal.pgen.1009816 (http://dx.doi.org/10.1371/journal.pgen.1009816)
Velot, Lauriane; Lessard, Frederic; Berube-Simard, Felix-Antoine; Tav, Christophe; Neveu, Bertrand; Teyssier, Valentine; Boudaoud, Imene; Dionne, Ugo; Lavoie, Noemie; Bilodeau, Steve; Pouliot, Frederic; Bisson, Nicolas. (2021). Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner. MOLECULAR & CELLULAR PROTEOMICS. DOI: 10.1016/j.mcpro.2021.100064 (http://dx.doi.org/10.1016/j.mcpro.2021.100064)
Soltani, Samira; Couture, Frederic; Boutin, Yvan; Ben Said, Laila; Cashman-Kadri, Samuel; Subirade, Muriel; Biron, Eric; Fliss, Ismail. (2021). In vitro investigation of gastrointestinal stability and toxicity of 3-hyrdoxy-propionaldehyde (reuterin) produced by Lactobacillus reuteri. TOXICOLOGY REPORTS. DOI: 10.1016/j.toxrep.2021.03.025 (http://dx.doi.org/10.1016/j.toxrep.2021.03.025)
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Cornuault, Jeffrey K.; Moineau, Sylvain. (2021). Induction and Elimination of Prophages Using CRISPR Interference. CRISPR JOURNAL. DOI: 10.1089/crispr.2021.0026 (http://dx.doi.org/10.1089/crispr.2021.0026)
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Plante, Samuel; Landry, Christian R.. (2021). Closely related budding yeast species respond to different ecological signals for spore activation. YEAST. DOI: 10.1002/yea.3538 (http://dx.doi.org/10.1002/yea.3538)
Berger, Caroline M.; Landry, Christian R.. (2021). Yeast proteins do not practice social distancing as species hybridize. CURRENT GENETICS. DOI: 10.1007/s00294-021-01188-x (http://dx.doi.org/10.1007/s00294-021-01188-x)
Rodriguez-Martinez, Aitor; Trapero, Carla; Vidal, August; Piulats, Josep Maria; Gomez de Aranda, Inmaculada; Sevigny, Jean; Fernandez-Montoli, Maria Eulalia; Ponce, Jordi; Matias-Guiu, Xavier; Martin-Satue, Mireia. (2021). Characterization of the Endometrial MSC Marker Ectonucleoside Triphosphate Diphosphohydrolase-2 (NTPDase2/CD39L1) in Low- and High-Grade Endometrial Carcinomas: Loss of Stromal Expression in the Invasive Phenotypes. JOURNAL OF PERSONALIZED MEDICINE. DOI: 10.3390/jpm11050331 (http://dx.doi.org/10.3390/jpm11050331)
Aziz, Hamid; Mahmood, Abid; Zaib, Sumera; Saeed, Aamer; El-Seedi, Hesham R.; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2021). Synthesis, characterization, alkaline phosphatase inhibition assay and molecular modeling studies of 1-benzylidene-2-(4-tert- butylthiazol-2-yl) hydrazines. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. DOI: 10.1080/07391102.2020.1802336 (http://dx.doi.org/10.1080/07391102.2020.1802336)
Schmidt, Thais F.; Riske, Karin A.; Caseli, Luciano; Salesse, Christian. (2021). Dengue fusion peptide in Langmuir monolayers: A binding parameter study. BIOPHYSICAL CHEMISTRY. DOI: 10.1016/j.bpc.2021.106553 (http://dx.doi.org/10.1016/j.bpc.2021.106553)
Klein, Brianna J.; Cox, Khan L.; Jang, Suk Min; Singh, Rohit K.; Cote, Jacques; Poirier, Michael G.; Kutateladze, Tatiana G.. (2021). Structural and biophysical characterization of the nucleosome-binding PZP domain. STAR PROTOCOLS. DOI: 10.1016/j.xpro.2021.100479 (http://dx.doi.org/10.1016/j.xpro.2021.100479)
Pham, N. T. Hang; Letourneau, Myriam; Fortier, Marlene; Begin, Gabriel; Al-Abdul-Wahid, M. Sameer; Pucci, Fabrizio; Folch, Benjamin; Rooman, Marianne; Chatenet, David; St-Pierre, Yves; Lague, Patrick; Calmettes, Charles; Doucet, Nicolas. (2021). Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7. JOURNAL OF BIOLOGICAL CHEMISTRY. DOI: 10.1016/j.jbc.2021.101308 (http://dx.doi.org/10.1016/j.jbc.2021.101308)
Dore, Laurie; Pageau, Gabrielle; Bourque-Leblanc, Francoise; Dupuis, Marie-Eve; Lessard-Hurtubise, Roxanne; Lacasse, Genevieve; Plante, Pier-Luc; Labrie, Simon; Jolicoeur, Alice P.; Rousseau, Genevieve M.; Tremblay, Denise M.; Moineau, Sylvain. (2021). Complete Genome Sequences of 10 Lactococcal Skunavirus Phages Isolated from Cheddar Cheese Whey Samples in Canada. MICROBIOLOGY RESOURCE ANNOUNCEMENTS. DOI: 10.1128/MRA.00098-21 (http://dx.doi.org/10.1128/MRA.00098-21)
Soltani, Samira; Hammami, Riadh; Cotter, Paul D.; Rebuffat, Sylvie; Ben Said, Laila; Gaudreau, Helene; Bedard, Francois; Biron, Eric; Drider, Djamel; Fliss, Ismail. (2021). Bacteriocins as a new generation of antimicrobials: toxicity aspects and regulations. FEMS MICROBIOLOGY REVIEWS. DOI: 10.1093/femsre/fuaa039 (http://dx.doi.org/10.1093/femsre/fuaa039)
Hosseini, Nava; Paquet, Valerie E.; Chehreghani, Mahdi; Moineau, Sylvain; Charette, Steve J.. (2021). Phage Cocktail Development against Aeromonas salmonicida subsp. salmonicida Strains Is Compromised by a Prophage. VIRUSES-BASEL. DOI: 10.3390/v13112241 (http://dx.doi.org/10.3390/v13112241)
Jungblut, Anne D.; Raymond, Frederic; Dion, Moira B.; Moineau, Sylvain; Mohit, Vani; Nguyen, Guillaume Quang; Deraspe, Maxime; Francovic-Fontaine, Elina; Lovejoy, Connie; Culley, Alexander I.; Corbeil, Jacques; Vincent, Warwick F.. (2021). Genomic diversity and CRISPR-Cas systems in the cyanobacterium Nostoc in the High Arctic. ENVIRONMENTAL MICROBIOLOGY. DOI: 10.1111/1462-2920.15481 (http://dx.doi.org/10.1111/1462-2920.15481)
Babou Kammoe, Romuald Brice; Kauffenstein, Gilles; Pelletier, Julie; Robaye, Bernard; Sevigny, Jean. (2021). NTPDase1 Modulates Smooth Muscle Contraction in Mice Bladder by Regulating Nucleotide Receptor Activation Distinctly in Male and Female. BIOMOLECULES. DOI: 10.3390/biom11020147 (http://dx.doi.org/10.3390/biom11020147)
Gagne, Laurence M.; Morin, Nadine; Lavoie, Noemie; Bisson, Nicolas; Lambert, Jean-Philippe; Mallette, Frederick A.; Huot, Marc-Etienne. (2021). Tyrosine phosphorylation of DEPTOR functions as a molecular switch to activate mTOR signaling. JOURNAL OF BIOLOGICAL CHEMISTRY. DOI: 10.1016/j.jbc.2021.101291 (http://dx.doi.org/10.1016/j.jbc.2021.101291)
Nabeel-Shah, Syed; Garg, Jyoti; Saettone, Alejandro; Ashraf, Kanwal; Lee, Hyunmin; Wahab, Suzanne; Ahmed, Nujhat; Fine, Jacob; Derynck, Joanna; Pu, Shuye; Ponce, Marcelo; Marcon, Edyta; Zhang, Zhaolei; Greenblatt, Jack F.; Pearlman, Ronald E.; Lambert, Jean-Philippe; Fillingham, Jeffrey. (2021). Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkab413 (http://dx.doi.org/10.1093/nar/gkab413)
Dion, Moira B.; Plante, Pier-Luc; Zufferey, Edwige; Shah, Shiraz A.; Corbeil, Jacques; Moineau, Sylvain. (2021). Streamlining CRISPR spacer-based bacterial host predictions to decipher the viral dark matter. NUCLEIC ACIDS RESEARCH. DOI: 10.1093/nar/gkab133 (http://dx.doi.org/10.1093/nar/gkab133)
Achigar, Rodrigo; Scarrone, Martina; Rousseau, Genevieve M.; Philippe, Cecile; Machado, Felipe; Duvos, Valentina; Campot, Maria Pia; Dion, Moira B.; Shao, Yuyu; Pianzzola, Maria Julia; Moineau, Sylvain. (2021). Ectopic Spacer Acquisition in Streptococcus thermophilus CRISPR3 Array. MICROORGANISMS. DOI: 10.3390/microorganisms9030512 (http://dx.doi.org/10.3390/microorganisms9030512)
Suzuki, Godai; Saito, Yutaka; Seki, Motoaki; Evans-Yamamoto, Daniel; Negishi, Mikiko; Kakoi, Kentaro; Kawai, Hiroki; Landry, Christian R.; Yachie, Nozomu; Mitsuyama, Toutai. (2021). Machine learning approach for discrimination of genotypes based on bright-field cellular images. NPJ SYSTEMS BIOLOGY AND APPLICATIONS. DOI: 10.1038/s41540-021-00190-w (http://dx.doi.org/10.1038/s41540-021-00190-w)
Fage, Clement; Lemire, Nicolas; Moineau, Sylvain. (2021). Delivery of CRISPR-Cas systems using phage-based vectors. CURRENT OPINION IN BIOTECHNOLOGY. DOI: 10.1016/j.copbio.2020.11.012 (http://dx.doi.org/10.1016/j.copbio.2020.11.012)
Fijarczyk, Anna; Henault, Mathieu; Marsit, Souhir; Charron, Guillaume; Landry, Christian R.. (2021). Heterogeneous Mutation Rates and Spectra in Yeast Hybrids. GENOME BIOLOGY AND EVOLUTION. DOI: 10.1093/gbe/evab282 (http://dx.doi.org/10.1093/gbe/evab282)
Mosterd, Cas; Moineau, Sylvain. (2021). Primed CRISPR-Cas Adaptation and Impaired Phage Adsorption in Streptococcus mutans. MSPHERE. DOI: 10.1128/mSphere.00185-21 (http://dx.doi.org/10.1128/mSphere.00185-21)
Metivier, Mathieu; Gallaud, Emmanuel; Thomas, Alexandre; Pascal, Aude; Gagne, Jean-Philippe; Poirier, Guy G.; Chretien, Denis; Gibeaux, Romain; Richard-Parpaillon, Laurent; Benaud, Christelle; Giet, Regis. (2021). Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly. CURRENT BIOLOGY. DOI: 10.1016/j.cub.2020.11.009 (http://dx.doi.org/10.1016/j.cub.2020.11.009)
Alhammad, Yousef M. O.; Kashipathy, Maithri M.; Roy, Anuradha; Gagne, Jean-Philippe; McDonald, Peter; Gao, Philip; Nonfoux, Louis; Battaile, Kevin P.; Johnson, David K.; Holmstrom, Erik D.; Poirier, Guy G.; Lovell, Scott; Fehr, Anthony R.. (2021). The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase. JOURNAL OF VIROLOGY. DOI: 10.1128/JVI.01969-20 (http://dx.doi.org/10.1128/JVI.01969-20)
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Elowe, Sabine. (2021). Adventures of the undead at kinetochores. MOLECULAR & CELLULAR ONCOLOGY. DOI: 10.1080/23723556.2021.1876511 (http://dx.doi.org/10.1080/23723556.2021.1876511)
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Iqbal, Jamshed; Basharat, Ayesha; Bano, Sehrish; Abid, Syed Mobasher Ali; Pelletier, Julie; Sevigny, Jean. (2021). Identification and Expression Analysis of CD73 Inhibitors in Cervical Cancer. MEDICINAL CHEMISTRY. DOI: 10.2174/1573406416666200925141703 (http://dx.doi.org/10.2174/1573406416666200925141703)
Marcus, Joshua M.; Hossain, Mohammed I.; Gagne, Jean-Philippe; Poirier, Guy G.; McMahon, Lori L.; Cowell, Rita M.; Andrabi, Shaida A.. (2021). PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons. NEUROCHEMISTRY INTERNATIONAL. DOI: 10.1016/j.neuint.2021.105077 (http://dx.doi.org/10.1016/j.neuint.2021.105077)
Haas, Clarissa B.; Lovaszi, Marianna; Pacher, Pal; de Souza, Priscila Oliveira; Pelletier, Julie; Leite, Rafael Olive; Sevigny, Jean; Nemeth, Zoltan; Braganhol, Elizandra; Hasko, Gyorgy. (2021). Extracellular ectonucleotidases are differentially regulated in murine tissues and human polymorphonuclear leukocytes during sepsis and inflammation. PURINERGIC SIGNALLING. DOI: 10.1007/s11302-021-09819-1 (http://dx.doi.org/10.1007/s11302-021-09819-1)
St-Gelais, Jacob; Giguere, Denis. (2021). Protecting-Group-Free Synthesis of GB1107: An Orally Active Galectin-3 Antagonist. SYNTHESIS-STUTTGART. DOI: 10.1055/a-1517-7177 (http://dx.doi.org/10.1055/a-1517-7177)
Billaud, Maud; Lamy-Besnier, Quentin; Lossouarn, Julien; Moncaut, Elisabeth; Dion, Moira B.; Moineau, Sylvain; Traore, Fatoumata; Le Chatelier, Emmanuelle; Denis, Catherine; Estelle, Jordi; Achard, Caroline; Zemb, Olivier; Petit, Marie-Agnes. (2021). Analysis of viromes and microbiomes from pig fecal samples reveals that phages and prophages rarely carry antibiotic resistance genes. ISME COMMUNICATIONS. DOI: 10.1038/s43705-021-00054-8 (http://dx.doi.org/10.1038/s43705-021-00054-8)
Rasouli, Hannaneh; Iliuta, Ion; Bougie, Francis; Garnier, Alain; Iliuta, Maria C.. (2021). Enzyme-immobilized flat-sheet membrane contactor for green carbon capture. CHEMICAL ENGINEERING JOURNAL. DOI: 10.1016/j.cej.2021.129587 (http://dx.doi.org/10.1016/j.cej.2021.129587)
Zarrouk, Karima; Zhu, Xiaojun; Goyette, Nathalie; Piret, Jocelyne; Shi, Rong; Boivin, Guy. (2021). Differential impact of various substitutions at codon 715 in region II of HSV-1 and HCMV DNA polymerases. ANTIVIRAL RESEARCH. DOI: 10.1016/j.antiviral.2021.105046 (http://dx.doi.org/10.1016/j.antiviral.2021.105046)
Lazarjan, Vahid Khojasteh; Gashti, Anahita Bakhshizadeh; Feshki, Mohamad; Garnier, Alain; Gosselin, Benoit. (2021). Miniature Fiber-Spectrophotometer for Real-Time Biomarkers Detection. IEEE SENSORS JOURNAL. DOI: 10.1109/JSEN.2021.3072578 (http://dx.doi.org/10.1109/JSEN.2021.3072578)
Vezina-Dawod, Simon; Perreault, Martin; Guay, Louis-David; Gerber, Nicolas; Gobeil, Stephane; Biron, Eric. (2021). Synthesis and biological evaluation of novel 1,4-benzodiazepin-3-one derivatives as potential antitumor agents against prostate cancer. BIOORGANIC & MEDICINAL CHEMISTRY. DOI: 10.1016/j.bmc.2021.116314 (http://dx.doi.org/10.1016/j.bmc.2021.116314)
Schaekel, Laura; Mirza, Salahuddin; Pietsch, Markus; Lee, Sang-Yong; Keuler, Tim; Sylvester, Katharina; Pelletier, Julie; Sevigny, Jean; Pillaiyar, Thanigaimalai; Namasivayam, Vigneshwaran; Guetschow, Michael; Mueller, Christa E.. (2021). 2-Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors. ARCHIV DER PHARMAZIE. DOI: 10.1002/ardp.202100300 (http://dx.doi.org/10.1002/ardp.202100300)
Niyonambaza, Shimwe Dominique; Koudrina, Anna; DeRosa, Maria C.; Boukadoum, Mounir; Miled, Amine; Boisselier, Elodie. (2021). Aptamer-Modified Ultrastable Gold Nanoparticles for Dopamine Detection. IEEE SENSORS JOURNAL. DOI: 10.1109/JSEN.2020.3026159 (http://dx.doi.org/10.1109/JSEN.2020.3026159)
Lachance, Gabriel P.; Soulard, Guillaume; Bouffard, Loic; Boisselier, Elodie; Boukadoum, Mounir; Miled, Amine. (2021). Colorimetric Sensing System for Neurotransmitter Detection Based on Multi-technologies Architecture. 2021 28TH IEEE INTERNATIONAL CONFERENCE ON ELECTRONICS, CIRCUITS, AND SYSTEMS (IEEE ICECS 2021). DOI: 10.1109/ICECS53924.2021.9665507 (http://dx.doi.org/10.1109/ICECS53924.2021.9665507)
Possamai, David; Hanafi, Laila-Aicha; Bellemare-Pelletier, Angelique; Hamelin, Katia; Thebault, Pamela; Hebert, Marie-Josee; Gagnon, Etienne; Leclerc, Denis; Lapointe, Rejean. (2021). MHC class I antigen cross-presentation mediated by PapMV nanoparticles in human antigen-presenting cells is dependent on autophagy. PLOS ONE. DOI: 10.1371/journal.pone.0261987 (http://dx.doi.org/10.1371/journal.pone.0261987)
Azizi, Dariush; Larachi, Faical; Garnier, Alain; Lague, Patrick; Levasseur, Benoit. (2021). Sorption of aqueous amino acid species on sulphidic mineral surfaces-DFTstudy and insights on biosourced-reagent mineral flotation. CANADIAN JOURNAL OF CHEMICAL ENGINEERING. DOI: 10.1002/cjce.23841 (http://dx.doi.org/10.1002/cjce.23841)
Guerin, Louis-Philippe; Le-Bel, Gaetan; Desjardins, Pascale; Couture, Camille; Gillard, Elodie; Boisselier, Elodie; Bazin, Richard; Germain, Lucie; Guerin, Sylvain L.. (2021). The Human Tissue-Engineered Cornea (hTEC): Recent Progress. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. DOI: 10.3390/ijms22031291 (http://dx.doi.org/10.3390/ijms22031291)
Sandhu, Bynvant; Perez-Matos, Maria C.; Tran, Stephanie; Singhal, Garima; Syed, Ismail; Feldbruegge, Linda; Mitsuhashi, Shuji; Pelletier, Julie; Huang, Jinhe; Yalcin, Yusuf; Csizmadia, Eva; Tiwari-Heckler, Shilpa; Enjyoji, Keiichi; Sevigny, Jean; Maratos-Flier, Eleftheria; Robson, Simon C.; Jiang, Z. Gordon. (2021). Global deletion of NTPDase3 protects against diet-induced obesity by increasing basal energy metabolism. METABOLISM-CLINICAL AND EXPERIMENTAL. DOI: 10.1016/j.metabol.2021.154731 (http://dx.doi.org/10.1016/j.metabol.2021.154731)
Gravel, Alexia; Marciniak, Alice; Couture, Manon; Doyen, Alain. (2021). Effects of Hexane on Protein Profile, Solubility and Foaming Properties of Defatted Proteins Extracted from Tenebrio molitor Larvae. MOLECULES. DOI: 10.3390/molecules26020351 (http://dx.doi.org/10.3390/molecules26020351)
Ascencio, Diana; Diss, Guillaume; Gagnon-Arsenault, Isabelle; Dube, Alexandre K.; DeLuna, Alexander; Landry, Christian R.. (2021). Expression attenuation as a mechanism of robustness against gene duplication. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. DOI: 10.1073/pnas.2014345118 (http://dx.doi.org/10.1073/pnas.2014345118)
Gilbert, Audrey; Birepinte, Melodie; Paquin, Jean-Francois. (2021). Electron donor-acceptor (EDA)-complex enabled SF5Cl addition on alkenes and alkynes. JOURNAL OF FLUORINE CHEMISTRY. DOI: 10.1016/j.jfluchem.2021.109734 (http://dx.doi.org/10.1016/j.jfluchem.2021.109734)
Murtaza, Amna; Afzal, Saira; Zaman, Gohar; Saeed, Aamer; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed; Hassan, Abbas. (2021). Divergent synthesis and elaboration of structure activity relationship for quinoline derivatives as highly selective NTPDase inhibitor. BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2021.105240 (http://dx.doi.org/10.1016/j.bioorg.2021.105240)
Gonay, Marie; Batisse, Chloe; Paquin, Jean-Francois. (2021). Recent Advances in the Synthesis of Acyl Fluorides. SYNTHESIS-STUTTGART. DOI: 10.1055/s-0040-1705951 (http://dx.doi.org/10.1055/s-0040-1705951)
Gilbert, Audrey; Langowski, Pauline; Paquin, Jean-Francois. (2021). Synthesis of N-(2-SF5-ethyl)amines and impact of the SF5 substituent on their basicity and lipophilicity. TETRAHEDRON. DOI: 10.1016/j.tet.2021.132424 (http://dx.doi.org/10.1016/j.tet.2021.132424)
Afzal, Saira; Al-Rashida, Mariya; Hameed, Abdul; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2021). Synthesis, In-vitro evaluation and molecular docking studies of oxoindolin phenylhydrazine carboxamides as potent and selective inhibitors of ectonucleoside triphosphate diphosphohydrolase (NTPDase). BIOORGANIC CHEMISTRY. DOI: 10.1016/j.bioorg.2021.104957 (http://dx.doi.org/10.1016/j.bioorg.2021.104957)
Iqbal, Jamshed; Jacob, Claus; Sevigny, Jean. (2021). Editorial: Metalloenzymes: Potential Drug Targets. FRONTIERS IN PHARMACOLOGY. DOI: 10.3389/fphar.2021.746925 (http://dx.doi.org/10.3389/fphar.2021.746925)
Moison, Celine; Chagraoui, Jalila; Caron, Marie-Christine; Gagne, Jean-Philippe; Coulombe, Yan; Poirier, Guy G.; Masson, Jean-Yves; Sauvageau, Guy. (2021). Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. DOI: 10.1073/pnas.2019408118 (http://dx.doi.org/10.1073/pnas.2019408118)
Gauvreau, Dominic; Lachance, Gabriel P.; Landari, Hamza; Boisselier, Elodie; Boukadoum, Mounir; Messaddeq, Younes; Miled, Amine. (2021). Finite Element Simulation of a Microdroplet Generation System for an Implantable Liquid Sampling Probe. 2021 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (IEEE BIOCAS 2021). DOI: 10.1109/BIOCAS49922.2021.9644950 (http://dx.doi.org/10.1109/BIOCAS49922.2021.9644950)
2020
Afzal, Saira; Al-Rashida, Mariya; Hameed, Abdul; Pelletier, Julie; Sevigny, Jean; Iqbal, Jamshed. (2020). Functionalized Oxoindolin Hydrazine Carbothioamide Derivatives as Highly Potent Inhibitors of Nucleoside Triphosphate Diphosphohydrolases. FRONTIERS IN PHARMACOLOGY. DOI: 10.3389/fphar.2020.585876 (http://dx.doi.org/10.3389/fphar.2020.585876)
Berube, Christopher; Borgia, Alexandre; Gagnon, Dominic; Mukherjee, Angana; Richard, Dave; Voyer, Normand. (2020). Total Synthesis and Antimalarial Activity of Dominicin, a Cyclic Octapeptide from a Marine Sponge. JOURNAL OF NATURAL PRODUCTS. DOI: 10.1021/acs.jnatprod.9b00936 (http://dx.doi.org/10.1021/acs.jnatprod.9b00936)
Baqi, Younis; Rashed, Mahmoud; Schaekel, Laura; Malik, Enas M.; Pelletier, Julie; Sevigny, Jean; Fiene, Amelie; Mueller, Christa E.. (2020). Development of Anthraquinone Derivatives as Ectonucleoside Triphosphate Diphosphohydrolase (NTPDase) Inhibitors With Selectivity for NTPDase2 and NTPDase3. FRONTIERS IN PHARMACOLOGY. DOI: 10.3389/fphar.2020.01282 (http://dx.doi.org/10.3389/fphar.2020.01282)
Lammers, Monica D.; Aneli, Nyasmin M.; de Oliveira, Gabriela G.; de Oliveira Maciel, Sarah F., V; Zanini, Daniela; Manica, Aline; de Resende e Silva, Debora T.; Bagatini, Margarete D.; Sevigny, Jean; De Sa, Clodoaldo A.; Manfredi, Leandro H.; Cardoso, Andreia M.. (2020). The anti-inflammatory effect of resistance training in hypertensive women: the role of purinergic signaling. JOURNAL OF HYPERTENSION. DOI: 10.1097/HJH.0000000000002578 (http://dx.doi.org/10.1097/HJH.0000000000002578)
Azambuja, J. H.; Schuh, R. S.; Michels, L. R.; Gelsleichter, N. E.; Beckenkamp, L. R.; Iser, I. C.; Lenz, G. S.; De Oliveira, F. H.; Venturin, G.; Greggio, S.; DaCosta, J. C.; Wink, M. R.; Sevigny, J.; Stefani, M. A.; Battastini, A. M. O.; Teixeira, H. F.; Braganhol, E.. (2020). Nasal Administration of Cationic Nanoemulsions as CD73-siRNA Delivery System for Glioblastoma Treatment: a New Therapeutical Approach. MOLECULAR NEUROBIOLOGY. DOI: 10.1007/s12035-019-01730-6 (http://dx.doi.org/10.1007/s12035-019-01730-6)
Nabeel-Shah, Syed; Ashraf, Kanwal; Saettone, Alejandro; Garg, Jyoti; Derynck, Joanna; Lambert, Jean-Philippe; Pearlman, Ronald E.; Fillingham, Jeffrey. (2020). Nucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila. SCIENTIFIC REPORTS. DOI: 10.1038/s41598-019-56867-0 (http://dx.doi.org/10.1038/s41598-019-56867-0)
Levesque, Sebastien; Agudelo, Daniel; Doyon, Yannick. (2020). Rewired Cas9s with Minimal Sequence Constraints. TRENDS IN PHARMACOLOGICAL SCIENCES. DOI: 10.1016/j.tips.2020.04.009 (http://dx.doi.org/10.1016/j.tips.2020.04.009)
Schaekel, Laura; Schmies, Constanze C.; Idris, Riham M.; Luo, Xihuan; Lee, Sang-Yong; Lopez, Vittoria; Mirza, Salahuddin; Vu, The Hung; Pelletier, Julie; Sevigny, Jean; Namasivayam, Vigneshwaran; Mueller, Christa E.. (2020). Nucleotide Analog ARL67156 as a Lead Structure for the Development of CD39 and Dual CD39/CD73 Ectonucleotidase Inhibitors. FRONTIERS IN PHARMACOLOGY. DOI: 10.3389/fphar.2020.01294 (http://dx.doi.org/10.3389/fphar.2020.01294)
Teixeira, Fernanda C.; Bruxel, Fernanda; Azambuja, Juliana H.; Berenguer, Alexandre M.; Stefani, Marco A.; Sevigny, Jean; Spanevello, Roselia M.; Battastini, Ana M. O.; Teixeira, Helder F.; Braganhol, Elizandra. (2020). Development and characterization of CD73-siRNA-loaded nanoemulsion: effect on C6 glioma cells and primary astrocytes. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY. DOI: 10.1080/10837450.2019.1705485 (http://dx.doi.org/10.1080/10837450.2019.1705485)
Lemay, Marie-Laurence; Maass, Sandra; Otto, Andreas; Hamel, Jeremie; Plante, Pier-Luc; Rousseau, Genevieve M.; Tremblay, Denise M.; Shi, Rong; Corbeil, Jacques; Gagne, Stephane M.; Becher, Doerte; Moineau, Sylvain. (2020). A Lactococcal Phage Protein Promotes Viral Propagation and Alters the Host Proteomic Response During Infection. VIRUSES-BASEL. DOI: 10.3390/v12080797 (http://dx.doi.org/10.3390/v12080797)
Mathieu, Aurelie; Dion, Moira; Deng, Ling; Tremblay, Denise; Moncaut, Elisabeth; Shah, Shiraz A.; Stokholm, Jakob; Krogfelt, Karen A.; Schjorring, Susanne; Bisgaard, Hans; Nielsen, Dennis S.; Moineau, Sylvain; Petit, Marie-Agnes. (2020). Virulent coliphages in 1-year-old children fecal samples are fewer, but more infectious than temperate coliphages. NATURE COMMUNICATIONS. DOI: 10.1038/s41467-019-14042-z (http://dx.doi.org/10.1038/s41467-019-14042-z)
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